Protein Alignment: CG1571 and DNAI1

• Sequence 1: NP_572435.1
• Gene: CG1571
• FlyBaseID: FBgn0029993
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001268357.1
• Gene: DNAI1
• HGNCID: 2954
• Length: 703
• Species: Homo sapiens
• Alignment Length: 656
• Identity: 122/657 (19%)
• Similarity: 226/657 (34%)
• Gaps: 198/657 (30%)

  Fly    16 GRQCRFQDRNELMVSVHPSGRQRLKYIM--------ANPSEKSTQLSRQ-------MALTVMETE 65
            ||:..::|  ||:...:...::.:|.|.        ..|.|..|:...|       .|..|.|.|
Human   118 GRRQHYRD--ELVAVSYQGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE 180

  Fly    66 NVTLDQHGMYHYEGGWPKE------VNFNDE---------------------------------- 90
            .:|..|          |||      .||::.
Human   181 LMTPKQ----------PKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIY 235

  Fly    91 ----EQTQRHRKKVERE------------------DSWGEQVLSMIRTTMSVAEQNNTLNIYQNF 133
                |:.::..|..|:|                  .|...|...:|:.:.:.......:|  ||.
Human   236 DAYVEELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVN--QNT 298

  Fly   134 FADLPPELGH--DIKMRFRARVANVFHDLWL----PARQL--RSIEWMPNNSRQFMTQYTNH-FA 189
            :.|:..:..:  |....:|.:|..:. .||.    .|::|  .::.|.|.....|...|.:: |.
Human   299 YDDIAQDFKYYDDAADEYRDQVGTLL-PLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDFM 362

  Fly   190 KGERLRPVTDEPFGGTNGFYVWDVKNPLKPRITYDSKQQVSLAKICPKDENNMVGGTGLGQVCL- 253
            |..|            ....::.:|||..|...:.|..                     |.:||
Human   363 KQSR------------GMLLLYSLKNPSFPEYMFSSNS---------------------GVMCLD 394

  Fly   254 ----------WGTFKGGLPIRNCPLEVSHRE---TTSALCWVHS-------------KSNTEFYS 292
                      .|.:.|.:.|.|  |:..|.:   .:||....||             ..|..|:|
Human   395 IHVDHPYLVAVGHYDGNVAIYN--LKKPHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFS 457

  Fly   293 GSLDGSIKYWDTRDLKM---PMQELLLEPEPQERQSRMDSHGV---TVLEFEYTIPVRFIIGSDM 351
            .|.||.|..|.....|:   .:.:|.:|....|....:..|.|   |..:|...|...|::|::.
Human   458 VSSDGRIVSWTLVKRKLVHIDVIKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEE 522

  Fly   352 GHVFVGNRKGMTP-METLLAHYQLFVGPVRSINRNPFFVKNFL-VTGDWRARIWSEEVKDSPSTM 414
            |.::..::...:. ::|..||..    .|.:::.||:..|.|: .:.||..:||...:| :|..:
Human   523 GKIYKCSKSYSSQFLDTYDAHNM----SVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIK-TPMFI 582

  Fly   415 YFRKNAQILCGAWSTGRCSLFVTGDINGVVDFWDLLLHH-----RKPIRSVDFKVAIADLVFRPE 474
            | ..|:.:...||:....::|.....:|....:||.::.     .:|:.:.  |..:..:.|...
Human   583 Y-DLNSAVGDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAAK--KNRLTHVQFNLI 644

  Fly   475 GDLLAIGLKNGDTHIMTLDESMRQATGKEKALMAAMFEREIVRCKLLE-ARYDEVRLKRKTLQMA 538
            ..::.:|...|....:.|..::|:...::|.       :|:.:...:| |:.|      |.|.:.
Human   645 HPIIIVGDDRGHIISLKLSPNLRKMPKEKKG-------QEVQKGPAVEIAKLD------KLLNLV 696

  Fly   539 EEERVR 544
            .|.:::
Human   697 REVKIK 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1571	NP_572435.1	WD40	210..462	CDD:295369	61/292 (21%)
		WD40	211..>488	CDD:225201	65/317 (21%)
		WD40 repeat	229..269	CDD:293791	8/51 (16%)
		WD40 repeat	277..325	CDD:293791	16/64 (25%)
		WD40 repeat	332..369	CDD:293791	8/41 (20%)
		WD40 repeat	379..415	CDD:293791	11/37 (30%)
		WD40 repeat	422..447	CDD:293791	4/25 (16%)
DNAI1	NP_001268357.1	WD40	324..681	CDD:225201	80/408 (20%)
		WD 1	324..374		11/63 (17%)
		WD40 repeat	339..385	CDD:293791	11/58 (19%)
		WD40	<357..615	CDD:295369	61/299 (20%)
		WD 2	379..417		9/61 (15%)
		WD40 repeat	391..428	CDD:293791	8/39 (21%)
		WD 3	426..469		12/43 (28%)
		WD40 repeat	439..496	CDD:293791	12/57 (21%)
		WD 4	478..530		11/52 (21%)
		WD40 repeat	504..541	CDD:293791	7/37 (19%)
		WD 5	535..574		12/43 (28%)
		WD40 repeat	547..584	CDD:293791	12/39 (31%)
		WD 6	578..616		8/39 (21%)
		WD40 repeat	589..616	CDD:293791	5/27 (19%)
		WD 7	622..662		5/42 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG1587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900