Protein Alignment snz and snx19b

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_021328604.2
• Gene: snx19b / 568980
• ZFINID: ZDB-GENE-030131-6331
• Length: 956
• Species: Danio rerio
• Alignment Length: 999
• Identity: 186/999 - (18%)
• Similarity: 347/999 - (34%)
• Gaps: 295/999 - (29%)

  Fly   145 QLQQIIEYVLRDFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVT 209
            ::|:.::.::|||:..|.. .|:..:...|.|...:.:...::..||.|:| .|.::..:::...
Zfish    95 EIQKTVDKIVRDFVTSWYS-TVSDEQEFEDEVHNAMISMAMELKGRASRVD-RKTLSQRVLDLSG 157

  Fly   210 VHLEKIRIAEARAAETNTPPVFSTNSYLADEEK-------EMEFLRKLCEIMVILLLPRGYSLPP 267
            .||:....|..:........::.|.|.|.....       |:.::|.:.::::.:|:|     ||
Zfish   158 CHLQGFLSASGKQEVDKDGDLWGTYSKLCPPHPALQSAAVEVNYVRAIVDLLLHVLVP-----PP 217

  Fly   268 L------KVLLSEILSYKIFFPMIKMLTAPDYINQKVV-------------QNIETR---LAAAA 310
            .      :.::.|:::..:..|:|..|:.||::|..:|             :.:|.:   ...:|
Zfish   218 HLETRTGRFVVGELITCNVILPLIAKLSDPDWLNLLIVSIFTQSSEPGSEPEPVEIQSPPQVVSA 282

  Fly   311 MSKRSYEYAASFEDFLKIINNSGNLEELS---LIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHS 372
            ......|.|......||:..::.|:.|.|   |....:: |.....:..||:         ||.|
Zfish   283 QENAQQELAVPCVLTLKVTPDTPNITEASTPELAAYDVI-DSAELFSPHNLE---------EDES 337

  Fly   373 LSKSELTAAVRLKRYVRQLTMAKGECEKNLAKFGWNGNY---SSDIDLTLVEILNTAVGRRYFTL 434
            .:..........:.|:|            |:|  .|..|   .||::..|.:....:
Zfish   338 RTTKPFPLGFSPRDYLR------------LSK--PNPFYQETDSDLESPLTDFKRGS-------- 380

  Fly   435 FLEPLKASALIGFYLAVEEIKHAHKSASHQLGTEIFYTYIRVPKSEIQIDKHERKLIETFL-LGD 498
                |::..|||          ..::.|.:| ||. .|.:. |..:::.|      :.|:. ..:
Zfish   381 ----LESLVLIG----------TEETLSERL-TEC-VTPVD-PLLDLEDD------LPTYTNTAE 422

  Fly   499 AEPDIFYDIQRNVLRTLEEKYYPPFVLSDQYRQLKEALDSNEIADPTLLMCHTIGDVQEPLADEQ 563
            .||...:.      .::.|:....|.......:...::|...:.:|..|..:|      |:....
Zfish   423 KEPSAAHS------ASVPEEEASSFCTLQPSEKCNSSIDQPGLLNPGDLALNT------PIQVTS 475

  Fly   564 PGAADGLNGGAGGAIDVAAHTSYARRKLEQIQERIDKKNQALDALKYSVKPESKVL--------T 620
            ||..                .|.|....|.:.                 .||..|:        |
Zfish   476 PGGM----------------ASLAPFNFEPLS-----------------SPEGPVIIQNLRITGT 507

  Fly   621 ILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINAPV 685
            |..|       |.|.|.:|     .:|.:..|::..:.    |:..||||             |:
Zfish   508 ITAK-------EHRGTGSH-----PYTLYTVKYETAMD----SENPESLQ-------------PL 543

  Fly   686 QPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAI-DLPTNFKFFFLK 749
            ...:.....|...||:.|             |.:..||::.|::|....|.. :||      |..
Zfish   544 AYHTVNRRYSEFLNLQTR-------------LEEKPELRKILKNVKGPKKIFPELP------FGN 589

  Fly   750 TDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSPSS------------------------- 789
            .|....|..|..::.||..:........||.:..||:.::
Zfish   590 MDSDKVEARKGLLETFLRQLCAIPETANSEEMQEFLALNTDARIAFVKKPFIVSRIDKIVVNAIV 654

  Fly   790 DHLKQSLP-----SP---------------KKSKFSLSTLFRSDAGKAHEAS-----------KA 823
            |.||.:.|     ||               ||||..:.  |.|....|...|           ::
Zfish   655 DTLKTAFPRSEPQSPTDDIDGEPDGKLSTDKKSKSRMR--FSSKIAPALSVSDMKPNVVYCFDES 717

  Fly   824 TDPFWGLQRDDEDISTYLDGESGGEAKMLAADLDSKDSI-------------AEPMY-------- 867
            :..|.|...:  ::.:::..:...|.|....|.|::.|:             |.|..
Zfish   718 STVFNGFLLN--ELESFISEKERSEGKAPGFDADAEKSVGSGPKLDLKTCMCARPQLENAPSFSE 780

  Fly   868 -----ALMGEIFD-----MGGVFKWL-RKSLISFVQITYGRTINRQIRESVAYLFEESMLHNYFS 921
                 ||..:..:     |...:.|| .:::...:::.:|..:.|.:...|..|........|..
Zfish   781 SAEETALSNQTLNILCMLMKNQWSWLCTENIQKTIRMLFGTLLERWLEVGVGNLTCTPYWVVYLQ 845

  Fly   922 AILKSFWPGGVL-ASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVFDALQ 985
            .:.::.||||.| |...|.||:..:|.:...|...|...:|:::.:::|::..|.....|.|:.|
Zfish   846 VLQEAIWPGGNLPAQPRPQRSQQQKEHSRKQALQCLMKLMPDLISDMLGSEKYKVFWQTVVDSFQ 910

  Fly   986 NPAYNKQLFYELLEILMIEFF-PE 1008
            :|..|:.|.|.|.: |:|||. ||
Zfish   911 DPTVNRHLVYCLWD-LLIEFLVPE 933

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	33/180 (18%)
		RGS_SNX25	422..531	CDD:188675	16/109 (15%)
		PX_SNX25	645..788	CDD:132788	30/143 (21%)
		Nexin_C	882..987	CDD:462541	25/106 (24%)
snx19b	XP_021328604.2	None