Protein Alignment snz and snx14

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_005160372.2
• Gene: snx14 / 555970
• ZFINID: ZDB-GENE-040724-144
• Length: 942
• Species: Danio rerio
• Alignment Length: 1093
• Identity: 215/1093 - (19%)
• Similarity: 382/1093 - (34%)
• Gaps: 314/1093 - (28%)

  Fly    66 YPTFFLFFAFVVYS----------LVLVFAAVAGTVYIHYIFTTNEPTPPSRVPSRLLYNATKSN 120
            ||..|..|..::.|          |::.::.:||.:..:...     :|...:|:.|:...||.
Zfish    27 YPVIFCIFTVMISSTIILNQYLHILMVFWSFLAGVITFYCSL-----SPEYLLPNILISIKTKR- 85

  Fly   121 IFDLPKPIKNPSNLPL-----IFGKT-------------------------VDLQLQQIIEYVLR 155
                 ||.:.....||     :.||.                         ||..:.:::|.||.
Zfish    86 -----KPQEQHELFPLGHSCAVCGKNQCKRHRPTLLLENYQPWLNLKVPSKVDASISEVLELVLE 145

  Fly   156 DFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRIAEA 220
            :|:.||. ..:|..:...|.:|:.:......:..||.|:|...::...|:.....|:|.|..|:.
Zfish   146 NFVYPWY-RDITDDEACVDELRQTIRFFAAVLAHRAQRVDVPSVVMDKMMKAAMKHIEIIAKAQQ 209

  Fly   221 RAAETNTPPVFSTNSYLAD-------EEKEMEFLRKLCEIMVILLLPRGYSLPP-------LKVL 271
            :...|:.....:...|.||       .:.|:.:||||.|    ||.|  |.:||       |.:|
Zfish   210 KVRNTDGLEQAALAEYGADLHVALRSRKDELLYLRKLTE----LLFP--YLMPPKATDCRSLALL 268

  Fly   272 LSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNLE 336
            :.|:::..:|.|::..:..||.:|..|:..|:
Zfish   269 IREVMTGSVFLPIMDFVADPDTVNHMVLIFID--------------------------------- 300

  Fly   337 ELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLKRYVRQLTMAKGECEKN 401
                                          |.....::....|....|:|:....|
Zfish   301 ------------------------------DTPPEPVTDPPSTLVPFLERFADPRT--------- 326

  Fly   402 LAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEE---------IKHA 457
                    ..||.:.|.|.||.........|..||:...|..::.|.|.|||         :...
Zfish   327 --------KKSSVLKLDLKEIREQQDLLFRFMSFLKEEGAVHVLQFCLTVEEFNDRILCPDLSDD 383

  Fly   458 HKSASHQLGTEIFYTYIRVPKSEIQIDKHERKLIETFLLGD----AEPD-----------IFYDI 507
            .|...|:...:|:.||.    .|..|||..   .:.|::.:    ||..           ..::.
Zfish   384 EKQRLHEEVKKIYETYC----LEESIDKIS---FDPFIIEEIHSIAEGPYTGVVKLQTMRCLFEA 441

  Fly   508 QRNVLRTLEEKYYPPFVLSDQYRQLKEALDSNEIADPTLLMCHTIGDVQEPLADEQPGAADGLNG 572
            ..:||..||:.:.|.|..||:|.:              .|:|          ..|.|.....||.
Zfish   442 YEHVLCLLEKVFTPMFCHSDEYFR--------------HLLC----------GAESPARNSKLNR 482

  Fly   573 GAGGAIDVAAHTSYARRKLEQIQ-ERIDKKNQAL---DALKYSVKPESKVL-----TILEKEMEW 628
            ..  ::|...:||   ::.|... .||..|.:.:   ..::.::.|:..::     |:.|..|.:
Zfish   483 NL--SLDDLRNTS---KRGESFGISRIGSKIKGVFKSSTMEGAMLPQYAMIEGEDDTVEEAVMVF 542

  Fly   629 LKSEKRQTEA-----HLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINAPVQPT 688
            ........:|     .||...|||       .:|..|:..|::...:.:.:..:|      |:..
Zfish   543 EDDSPGPMDAVGTPGTLRNLSAWT-------ISIPYVDFYDDEVKKERIPVFCID------VERN 594

  Fly   689 SSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAIDLPT-------NFKFF 746
            ..||  .||.         :..|.|.|...:.:.|:.||.......:...||:       |::|.
Zfish   595 DRKN--VGHE---------TESWSVYRKYVEFYVLESKLTEFHGPFQDAQLPSKRIIGPKNYEFL 648

  Fly   747 FLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSP---SSDHLKQSLPSPKKSKFSLST 808
            ..|         :.:.:::|..:|....|:.|:.:..||||   .|....:.||.     .:|..
Zfish   649 SSK---------RGEFEEYLQKLLHHPELSNSQLLADFLSPFSMESQFRDKMLPD-----VNLGK 699

  Fly   809 LFRSDAGK-AHEASKATDPFWGLQRDDEDISTYLDGESGGEAKMLAADLDSKDSIAEPMYA---- 868
            :|:|..|| ..|..:..:||  :|.......:.....|..|..:|:...::...:...:|.
Zfish   700 IFKSVPGKLIKEKGQNLEPF--IQSFFSSCESPKPKPSRPELTILSPTAENNKKLFNELYRNNAN 762

  Fly   869 ------------LMGEIFDMGG-----------VFK---WLRKSLISFVQITYGRTINRQIRESV 907
                        ...|:.::.|           ||:   ||. .|:|.|:|...||:...:....
Zfish   763 LPEGLEKKHNQNYFMELMEVDGAYDYMMYIGRVVFRMPDWLH-HLLSGVRILLKRTLEAYVGHYF 826

  Fly   908 AYLFEESM-LHNYFSAILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQ 971
            .|..|:.| .|...|  |.:.....|...:...||.:.::.........:.:::|:::...:|.:
Zfish   827 QYKLEQIMEEHRLVS--LVTLLRDAVFCESTEERSPEDKQRRAKQTFEEMMNYLPDIVGKCIGEE 889

  Fly   972 AAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEIRQLRVSNSNGTKLNT 1024
            |...||..:|:.:|.|..|||:.|.||:|.:.|.|||:.:   :...|..::|
Zfish   890 AKYDGVKMLFNTIQQPLLNKQMTYVLLDIAIQELFPELSK---NQKQGLSVST 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	45/171 (26%)
		RGS_SNX25	422..531	CDD:188675	31/132 (23%)
		PX_SNX25	645..788	CDD:132788	31/152 (20%)
		Nexin_C	882..987	CDD:462541	24/105 (23%)
snx14	XP_005160372.2	None