Protein Alignment snz and Snx14

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_063121634.1
• Gene: Snx14 / 315871
• RGDID: 1310921
• Length: 985
• Species: Rattus norvegicus
• Alignment Length: 1135
• Identity: 227/1135 - (20%)
• Similarity: 396/1135 - (34%)
• Gaps: 363/1135 - (31%)

  Fly    14 RRLPLFPIEPEPSVTATQRLTLLATRLLRALQLNWRIIVSGITL-------TLLAVIWYYPTFFL 71
            |:.|||..    .:......:||..|.|..|.:.|..:...:|.       :||      |..|.
  Rat    53 RQYPLFCF----LLLCLSAASLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLL------PNIFF 107

  Fly    72 FFAFVVYSLVL--VF-----AAVAGTVYIHYIFTTNEPTPPSRVPSRLLYNATKSNIFDLPKPIK 129
            ...:....|.|  :|     .||.|.|..           ....||.||.|.         :|.
  Rat   108 TIKYKPKQLGLQELFPQGHSCAVCGKVKC-----------KRHRPSLLLENY---------QPW- 151

  Fly   130 NPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKPKLINDV---VREDLWNAIQKIHERA 191
                |.|.....||..|.:::|.||.:|:.||...|......::::   :|......:::||
  Rat   152 ----LDLKVSSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIH--- 209

  Fly   192 LRMDAAKIIAVDMVNRVTVHLEKIRIAEARAAETNTPPVFSTNSY-------LADEEKEMEFLRK 249
             ::|...||...::.....|:|.|..|..:...|......:...|       |.....|:::|||
  Rat   210 -KVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEYLQQAALEEYGPDLHVALRSRRDELQYLRK 273

  Fly   250 LCEIMVILLLPRGYSLPP-------LKVLLSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLA 307
            |.|    ||.|  |.|||       |.:|:.||||..:|.|.:..|..||.:|..::..|:.
  Rat   274 LTE----LLFP--YILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDD--- 329

  Fly   308 AAAMSKRSYEYAASFEDFLKIINNSGNLEELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHS 372
              :..:::.|.|:....||:                                  |..:|.::..|
  Rat   330 --SPPEKATEPASPLVPFLQ----------------------------------KFAEPRNKKPS 358

  Fly   373 LSKSELTAAVRLKRYVRQLTMAKGECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLE 437
            :.|.||       :.:|:                     ..|:   |...:|          ||:
  Rat   359 VLKLEL-------KQIRE---------------------QQDL---LFRFMN----------FLK 382

  Fly   438 PLKASALIGFYLAVEEIKHAHKSASHQLGTEIFYTYIRVPKSEIQIDK----HE--RKLIETFLL 496
            ...|..::.|.|.|||...                  |:.:.|:..|:    ||  :|:.:|:.|
  Rat   383 QEGAVHVLQFCLTVEEFND------------------RILRPELSNDEMLSLHEELQKIYKTYCL 429

  Fly   497 GDA------EPDIFYDIQR-----------------------NVLRTLEEKYYPPFVLSDQY-RQ 531
            .::      :|.|..:|||                       :||..||..:.|.|..||:| ||
  Rat   430 DESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQ 494

  Fly   532 LKEALDSNEIADPTLLMCHTIGDVQEPLAD----EQPGAADGLNGGAGGAIDVAAHTSYARRKLE 592
            |....:|     ||.......|.:.  |.|    ::.|.:.|::
  Rat   495 LLRGAES-----PTRNSKFNRGSLS--LDDFRSTQKRGESFGIS--------------------- 531

  Fly   593 QIQERIDKKNQALDALKYSVKPESKVLT---ILEKEMEWLK------SEKRQTEAHLRRTDAWTE 648
                ||..|   :..:..|...|..||.   :.|.|.::::      .:....||  ..|.....
  Rat   532 ----RIGSK---IKGVFKSTTMEGAVLPSYGVAEGEDDFIEEGIVVLEDDSPVEA--VSTPNTPR 587

  Fly   649 HLGKWKATIQSVEV-----SDEKESLQFMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGIS 708
            :|..||.:|..|:.     |:.||..:.:.:..:|.:                 .|.|:......
  Rat   588 NLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVE-----------------RNDRRAVGHEP 635

  Fly   709 SGWVVMRSLNQVHELQRKLRHVSSNLKAIDLPT-------NFKFFFLKTDRHGQEKAKSQIQKFL 766
            ..|.|.|...:.:.|:.||...........||:       |::  |||:.|       .:.|::|
  Rat   636 EHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYE--FLKSKR-------EEFQEYL 691

  Fly   767 NFILEDDHLNGSEAIYTFLSPS---SDHLKQSLPSPKKSKFSLSTLFRSDAGK-AHEASKATDPF 827
            ..:::...|:.|:.:..||||:   :..|.:.||.     .:|..:.:|..|| ..|..:..:||
  Rat   692 QKLVQHPELSNSQLLADFLSPNGGETQFLDKILPD-----VNLGKIIKSVPGKLMKEKGQHLEPF 751

  Fly   828 WGLQRDDEDISTYLDGESGGEAKMLAADLDSKDSIAEPMYALMGEIF------------------ 874
                     |.::::.....:.|....:|......:|....|..::|
  Rat   752 ---------IMSFINSCESPKPKPSRPELTILSPTSENNKKLFNDLFKNNANRAENTERKQNQNY 807

  Fly   875 -----DMGGVF--------------KWLRKSLISFVQITYGRTI----NRQIRESVAYLFEESML 916
                 .:.||:              .||...|:. .:|.:..|:    :..::..:..||:|..|
  Rat   808 FMEVMTVDGVYDYLMYVGRVVFQVPDWLHHLLMG-TRILFKNTLEMYTDYYLQCKLEQLFQEHRL 871

  Fly   917 HNYFSAILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVF 981
            .:..:.:..:.:    ..:..|...:|.::......:.:: ::||:::...:|.:.....:..:|
  Rat   872 VSLITLLRDAIF----CENTEPRSLQDKQKGAKQTFEEMM-NYIPDLIVKCIGEETKYESIRLLF 931

  Fly   982 DALQNPAYNKQLFYELLEILMIEFFPEIRQ 1011
            |.||.|..||||.|.||:|::.|.|||:.:
  Rat   932 DGLQQPVLNKQLTYVLLDIVIQELFPELNK 961

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	48/174 (28%)
		RGS_SNX25	422..531	CDD:188675	31/144 (22%)
		PX_SNX25	645..788	CDD:132788	31/154 (20%)
		Nexin_C	882..987	CDD:462541	18/108 (17%)
Snx14	XP_063121634.1	None