Protein Alignment snz and Snx19

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: NP_001101601.2
• Gene: Snx19 / 315478
• RGDID: 1309857
• Length: 997
• Species: Rattus norvegicus
• Alignment Length: 1174
• Identity: 202/1174 - (17%)
• Similarity: 371/1174 - (31%)
• Gaps: 393/1174 - (33%)

  Fly    49 RIIVSGITLTLLAVIWYYPTFFLFFAFVVYSLVL-------VFAAVAGTVYIHYI--FTTNEPTP 104
            :::|.|:.|..|.||......:|........:||       .....:|.:::...  .||..|.|
  Rat    28 KLMVVGVLLGWLLVIHLLVNVWLLILLCASLVVLGGWLGSTAIVGASGQLHLERFISITTCPPCP 92

  Fly   105 PSRVPSRLLYNATKSNIFDLPKPIKNPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKP 169
            .:.                                :.::.::...|:.::|||:|.|. ..|:..
  Rat    93 EAE--------------------------------RHLEQEINCTIQMIIRDFVLSWY-RSVSHE 124

  Fly   170 KLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTV----HLEK-IRIAEARAAETNTP- 228
            |.....:...:...:|::..|...:|:..     :..||..    ||:. |:...|.|.|.:.|
  Rat   125 KTFEAEMEASMKGLVQELRRRMSIVDSHA-----LTQRVLTLCGCHLQSYIQAKGATAKEQSCPV 184

  Fly   229 ----------PVFSTNSYLADEEKEMEFLRKLCEIMVILLLPRGYSLPPLKV-----LLSEILSY 278
                      .|.:.:..::....|:.:.|.:..:::..|:|:    |.|:.     ::.|:::.
  Rat   185 EPSQLWDAYCQVTTPHPAMSCPTTEVTYARGIVNLILKELVPK----PHLETRTGRHVVVELITC 245

  Fly   279 KIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNLEELSLIRK 343
            .:..|:|..|:.||:|:..:|         :..||  |:..|
  Rat   246 NVILPLISKLSDPDWIHLILV---------SIFSK--YKQDA----------------------- 276

  Fly   344 SIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLKRYVRQLTMAKGECEKNLAKFGWN 408
                             |:|..|......|.:..:..::.|...|..|.:.|.
  Rat   277 -----------------AQGTKPPSSPCVLEQPSVPTSLPLMVEVESLPVGKA------------ 312

  Fly   409 GNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVE-------EIKHAHKSASHQLG 466
                           ::.|.........||..:..:...:.|||       |.:....::||.|.
  Rat   313 ---------------SSPVAAPVHLASSEPAPSPEIEEGHEAVEGELPGMLEERKVGNNSSHFLQ 362

  Fly   467 TEIFYTYIRVPKSEIQIDKHERKLIETFLLGDAEPDI-FYDIQRNVLRTLEEKYYPPFVLSDQYR 530
            .:     ||.|               .||..|:|.:. ..::.:..:..:.    |...||.:.:
  Rat   363 PD-----IRGP---------------LFLCEDSELESPLSELGKETIMLMT----PGNFLSHRIQ 403

  Fly   531 QLKEALDSNEIADPTLLMCHTIGDVQEPL----ADEQPGAADGLNGGAGGAIDVAAHTSYARRKL 591
            ....|||.::..:|      ..|:..|.:    |:|.|||            :....|..:....
  Rat   404 DALCALDDSQALEP------RDGEGSECMEGAEAEEAPGA------------ETETGTLVSMLNC 450

  Fly   592 EQIQERIDKKNQALDALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGKWKAT 656
            .:||  ||      .|.|.:.:.:...||.|.:|.|         :..|:|.....:.||....:
  Rat   451 PEIQ--ID------PADKEAEQGDDASLTALLEEPE---------KPCLQRPSCLDKGLGSGACS 498

  Fly   657 IQ--------SVEVSDEKESLQFMILVHVDEDINAPVQPTSSKN-------------GDSGH--- 697
            ::        |........|..|..     |.:::|..|...:|             |...|
  Rat   499 LEPAVPPLSLSSSPPGPLSSATFSF-----ESLSSPDGPVVIQNLRITGTITAREHSGTGFHPYT 558

  Fly   698 ---ANLRKRPSGISSGWVVMRSLNQVHELQRK-------------LRHVSSNLKA-----IDLPT 741
               .......||.:|..:...:.:.|:...|:             ||....|:|.     .|||
  Rat   559 LYTVKYETALSGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLP- 622

  Fly   742 NFKFFFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSPSSD----HLKQSLPSPKKS 802
               |..:.:||  .|..||.::.||..:.....:..||.:..||:.::|    .:|:.....:..
  Rat   623 ---FGNMDSDR--VEARKSLLESFLRQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRID 682

  Fly   803 KFSLSTLFRSDAGK-AHEASKATDPFWGLQRDDEDISTYLDGESGGEAKM------LAADLDSKD 860
            |..:|.:.  |..| |...|:...|...|...:.:.....:|:...::::      :|..|...:
  Rat   683 KMVVSAIV--DTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKASKSRLRFSSSKIAPALSIAE 745

  Fly   861 SIAEPMYALM-----GEIFDMGGV----------------------------------------- 879
            :..:.:|.|.     .|:..|.|:
  Rat   746 AQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLQMQPAEVPDKEPQQVPKESVDSGLLDKAVV 810

  Fly   880 ------------------------------FKWL-RKSLISFVQITYGRTINRQIRESVAYLFEE 913
                                          :||| .:::..|:::.:|..:.|.:...||.|...
  Rat   811 SQELNKSDPGTETELADTAFDLILLLLMEQWKWLCTENMQKFLRLVFGTLVQRWLEVQVANLTCP 875

  Fly   914 SMLHNYFSAILKSFWPGGVLAS-AYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGV 977
            .....|...:.:|.||||||.. ..|.|::..:..|...|...|...:|:.|..::|....:...
  Rat   876 QRWAQYLRLLRESIWPGGVLPKFPRPGRTQAQKAATEKQALQSLMGLLPDFLVEILGVHKCQLSW 940

  Fly   978 LKVFDALQNPAYNKQLFYELLEILMIEFFPEIRQLRVSNSNGTKLNTATAGAAAASAAAALVAAT 1042
            ..|.::.|.|..|:.|.|.|.:|: :||..                        .|||....|.|
  Rat   941 SLVLESFQQPLINRHLIYCLGDII-LEFLD------------------------LSAAVEECAPT 980

  Fly  1043 ASAS 1046
            .|||
  Rat   981 TSAS 984

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	34/178 (19%)
		RGS_SNX25	422..531	CDD:188675	20/116 (17%)
		PX_SNX25	645..788	CDD:132788	35/187 (19%)
		Nexin_C	882..987	CDD:462541	26/106 (25%)
Snx19	NP_001101601.2	None