Protein Alignment snz and Kif16b

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_038960967.1
• Gene: Kif16b / 311478
• RGDID: 1310146
• Length: 1876
• Species: Rattus norvegicus
• Alignment Length: 1085
• Identity: 189/1085 - (17%)
• Similarity: 344/1085 - (31%)
• Gaps: 389/1085 - (35%)

  Fly   119 SNIFDLPKPIKNPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKPKLINDVVREDLWNA 183
            |.:.||.:...|    ||:..|      |..:.|  ||.:|.||             :::.|..
  Rat   290 SALADLSQDAAN----PLVKKK------QVFVPY--RDSVLTWL-------------LKDSLGG- 328

  Fly   184 IQKIHERALRMDAAKIIAVDMVNRVTVH----LEKIRIAEARAAETNTPPVFSTNSYLADEEKEM 244
                        .:|.|.:..::...|:    |..:|.|.......|.|.:        :|:..:
  Rat   329 ------------NSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTI--------NEDANV 373

  Fly   245 EFLRKL-CEIMVILLLPRGYSLPPLKVLLSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAA 308
            :.:|:| .||            ..||.||::       ...|.:|.:|               .|
  Rat   374 KLIRELRAEI------------ARLKTLLAQ-------GNQIALLDSP---------------TA 404

  Fly   309 AAMSKRSYEYAASFEDFLKIINNSGN-----LEELSL-IRKSIVNDLMHATTMQNLQRAKGLDPD 367
            .:|.::.::..|..::..|...|..|     |:|.:| :||..:..::.:    .|....|:|
  Rat   405 LSMEEKLHQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDS----ELPHLIGID-- 463

  Fly   368 HEDHSLSKSELTAAVRLKRYVRQLTMAKGECEKNLAKFGWNGNYSSDIDLTLVE-ILNTAVGRRY 431
              |..||...:  ...||.....:.......|:::...|        :||.... :...|.|
  Rat   464 --DDLLSTGII--LYHLKEGQTYVGREDASTEQDIVLHG--------LDLESEHCVFENAGG--- 513

  Fly   432 FTLFLEPLKASALIGFYLAVEEIKHAHKSASHQLGTEIFYTYIRVPKSEIQI-DKHERKLIETFL 495
             |:.|.||..|......:.:.:....::.|...||....:.: ..||...:: :|.:..|:.:|.
  Rat   514 -TVTLIPLSGSQCSVNGVQIVDATQLNQGAVILLGRTNMFRF-NHPKEAAKLREKRKSGLLSSFS 576

  Fly   496 LGDAE---------------PDI------------FYDIQRNVLRTLEEKYYPPFVLSDQYRQLK 533
            |...:               |.:            |...||..|..||.|           |:|.
  Rat   577 LSMTDLSKSCENLSAVMLYNPGLFPMKGPICLRLEFERQQREELEKLESK-----------RKLI 630

  Fly   534 EALDSNEIADPTLLMCHTIGDVQEPLADEQPGAADGLNGGAGGAIDVAAHTSYARRKLEQIQERI 598
            |.::..:.:|...|         |.:..|                     ....|::.|.:|.:|
  Rat   631 EEMEEKQKSDKAEL---------ERMQQE---------------------VETRRKETEIVQRQI 665

  Fly   599 DKKNQALDALKYSVKPESKVLTILE----------KEMEWLKSEKRQTE-------AHLRRTDAW 646
            .|:.::|....:.:  |:|:..:|.          :|.:.|:.:|||.|       ..|||....
  Rat   666 RKQEESLKRRSFHI--ENKLKDLLAEKERFEEERLREQQGLEQQKRQEEDSFFRIREELRRLQEL 728

  Fly   647 TEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGISSGW 711
            ..|           |.:::.:.||.:..:|.::|            ..|....|.||
  Rat   729 NSH-----------EQAEKGQPLQDLDWLHREQD------------AQSAKLQLEKR-------- 762

  Fly   712 VVMRSLNQVHELQRKLRHVSSNLKAIDLPTNFKFFFLKTD----------RHGQEKAKSQIQKFL 766
               |...|..|...::.|:...|:.            :.|          :..||: :.:::...
  Rat   763 ---RLEEQEKEQVLRVAHLEEQLRK------------RQDTAPLLCPGEAQQAQEE-RRELEGIR 811

  Fly   767 NFILEDDHLN-GSEAIYTFLSPSSDHLKQSLPSPKKSKFSLSTLFRSDAGKAHEASKATDPFWGL 830
            ..:|:...:. |.:  :||........:..|...::....|:||.:....:....||..
  Rat   812 GALLQAKEIRAGGD--HTFRGELERAQQYFLEFKRRQLVKLATLEKDLVQQKDRLSKEV------ 868

  Fly   831 QRDDEDISTYLDGESGGEAKMLAAD--------------------LDSK-----DSIAEPMYALM 870
             :::::...::..|:|.|..:||.|                    |.||     |.:...:.||:
  Rat   869 -QEEKEALEHVKCEAGEEPSLLATDNCNILCGPQDLDKIKTAESRLQSKEHQLQDLLQNHLPALL 932

  Fly   871 G------EIFDMG-----GVFKWLRK----------------SLISFVQITYGRTIN-------- 900
            .      ||.|.|     .:...:.|                |.:..:|.|...|.|
  Rat   933 EEKQRVLEILDCGVLGLDNILYHVEKEMEEKEEQITQYQANASQLQQLQATVQFTANVARQEEKV 997

  Fly   901 ----RQIRESVAYLFEESM------LHNYFSAILK--------------------SFWPG----- 930
                ::|.||......|::      |....||:.:                    |.|||
  Rat   998 RRKEKEILESQEKQQREALEQAVAKLEQRHSALKRRSTLDLEIQEQRQKLGSLHSSEWPGLQASL 1062

  Fly   931 ---GVLASAYPTRSE-DMREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVFDALQN--PAY 989
               |......|.|.| ::.|             :.:.:|.:.|.|....|.|:...||.:  |:.
  Rat  1063 EANGERLQMDPARIEHEIHE-------------LKQKICEVDGVQRPHHGTLEGKAALSSLPPSA 1114

  Fly   990 NKQLFYELLEILMIEFFPEIRQLRVSNSNGTKLNTATAGAAAASA 1034
            .......|::..:..:..|..|.|:.:     |:...:.|:.|.|
  Rat  1115 ENSHLAPLMDARISAYIEEEVQRRLHD-----LHRVISDASHAPA 1154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	28/162 (17%)
		RGS_SNX25	422..531	CDD:188675	24/136 (18%)
		PX_SNX25	645..788	CDD:132788	22/153 (14%)
		Nexin_C	882..987	CDD:462541	29/169 (17%)
Kif16b	XP_038960967.1	KISc_KIF1A_KIF1B	15..368	CDD:276816	23/123 (19%)
		Kinesin_assoc	367..479	CDD:465047	31/163 (19%)
		FHA	449..565	CDD:469597	24/138 (17%)
		Smc	<609..>1087	CDD:440809	98/589 (17%)