Protein Alignment snz and mug122

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: NP_587808.1
• Gene: mug122 / 2539235
• PomBaseID: SPCC1682.15
• Length: 749
• Species: Schizosaccharomyces pombe
• Alignment Length: 945
• Identity: 169/945 - (17%)
• Similarity: 320/945 - (33%)
• Gaps: 304/945 - (32%)

  Fly    51 IVSGITLTLLAVIWYYPTFFLFFAFVVYSLVLVFAAVAGTVYIHYIFTTN-------------EP 102
            ::..|.|.:|::|:|    .|:..|...|.:|  :.:....|::.:|..|             ||
pombe    21 VIPIIALLVLSLIFY----ILYICFGTTSYIL--SGIILGAYVNSLFHNNHSVILNIKHPELGEP 79

  Fly   103 TPPSRVPSRLLYNATKSNIFDLPKPIKNPSNLPLIFGKTVD-----------------LQLQQII 150
            ..|.:.|              ||..::.|  |.|:..|...                 .::|..|
pombe    80 LKPYQTP--------------LPPELEAP--LQLLISKLTQHYINGWYKHVSEDPSFIREVQSTI 128

  Fly   151 EYVLRDFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKI 215
            ||::|.|      |.....:..:.::.|.|.|||          ....::..|:.:   ...:||
pombe   129 EYIMRQF------YAYVSSQESSHIIYELLKNAI----------STTTLVLSDLNH---FRSKKI 174

  Fly   216 RIAE--ARAAETNTPPVFSTNSYLADEEKEMEFLRKLCEIMVI-LLLPRGYSLPPLKVLLSEILS 277
            .:.|  .|..|       |..|.|.|:......||.....|:: ...|...:..||..||.|:|:
pombe   175 PLTEFALRYPE-------SAVSKLLDQASIERTLRAQASAMIVKFSRPEDSACLPLHCLLREVLA 232

  Fly   278 YKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNLEELSLIR 342
            .::|..:....::|.::|:.::.                 |.:|.||           :...|.:
pombe   233 MQVFKRITTHCSSPRFVNRCIIL-----------------YFSSSED-----------KSDCLAK 269

  Fly   343 KSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLK-RYVRQLTMAKGECEKNLAKFG 406
            |:.||..:.|..:::......:|||....|...:...|.:.|. :::::.:
pombe   270 KNYVNKCLMAKALKDYPVHTNIDPDAGKLSFDDAFYEAHIELHYQFLKEAS-------------- 320

  Fly   407 WNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEEIKHAHKSASHQLGTEIFY 471
                            |||.:            |...::.|.:.|..: |.|.|      ..:.|
pombe   321 ----------------LNTLI------------KDKKMLKFIITVRPV-HLHVS------PWVVY 350

  Fly   472 TYIRVPKSEIQIDKHERKLIETFLLGDAEPDIFYDIQRNVLRTLEEKYYPPFVL--SDQYRQLKE 534
            ...|..|:                       ::|.:::...|  ..:..|.|.:  .:.|.:.:|
pombe   351 RRYRGFKT-----------------------LYYLLKKQSAR--NGRAVPSFPVWRGNTYEKFRE 390

  Fly   535 AL---------DSNEIADPTLLMCHTIGDVQEPLADEQPGAADGLNGGAGGAIDVAAHTSYARRK 590
            .|         ||:...:..:...........||.|      |..||     .||
pombe   391 GLYFFIEALLHDSHFATNVDVRKFFAKSMRSHPLVD------DIYNG-----FDV---------- 434

  Fly   591 LEQIQERIDKKNQALDALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDAWTEHLG--KW 653
                    |||:|:      |..|....||.:.:.:    |.|....|..:|    :|..|  ..
pombe   435 --------DKKHQS------SSVPTLPNLTNISRVL----SNKTSKSAKPKR----SERTGLLSH 477

  Fly   654 KATIQSVEVSDEKESLQFMILVHVD---------EDINAPVQPTSSKNGDSGHANLRKRPSGISS 709
            ::|:....:|.:::|.:.....:.|         :.|:.|.:|.|::..::..|    .|....|
pombe   478 QSTLAPEPLSQQRDSFELCTTGYRDTGSCTSDDEDSIHEPYRPASTQPTENPPA----MPDHNGS 538

  Fly   710 GWVVMRSLNQVHELQRKLRH-VSSNLKAID--LPTNFKFFFLK---------TDRHGQEKAKSQI 762
            ........|.....:.:|:. :|.....:|  ...|.|.:|.:         |..||..:..:|:
pombe   539 PTTEPPKPNAFELKEERLKEIISGGFALVDELCSLNSKLWFFRKSVLTIMKTTVLHGPGRFSAQV 603

  Fly   763 QKFL-NFILEDDHLNGSEAIYTFLSPSSDHLKQSL-----PSPKKSKFSLST-----------LF 810
            ::.| |.|.  |.|:.::.:...|:        ||     |..||:..|.||           .|
pombe   604 ERMLKNQIY--DKLSNTQLVGDLLT--------SLILNVWPDEKKAMESHSTRAHRRSTESKISF 658

  Fly   811 RSDAGKAHEASKATDPFWGLQRDDEDISTYLDGESGGEAKMLAADLDSKDSIAEPMYALMGEIF- 874
            .|:|....|.:..:.|       ::.:|.:.|.||....::.|.....:::::|....::|:..
pombe   659 DSEADSLFEEASKSVP-------EDPVSVFCDEESDESLRLRAEKTLVENALSENFTLMLGQSTS 716

  Fly   875 --DMGGVFKWLRKSLISFVQITYGRTINRQIRESV 907
              .:..:|:.|::.  .|||......::..:|..:
pombe   717 EESLKIIFELLQEP--QFVQGFLAHLLSNALRSII 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	35/177 (20%)
		RGS_SNX25	422..531	CDD:188675	17/110 (15%)
		PX_SNX25	645..788	CDD:132788	30/166 (18%)
		Nexin_C	882..987	CDD:462541	5/26 (19%)
mug122	NP_587808.1	PXA	88..261	CDD:214611	42/217 (19%)
		PX_domain	326..415	CDD:132768	18/120 (15%)
		Nexin_C	578..731	CDD:462541	33/171 (19%)