Protein Alignment snz and Snx13

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: NP_001395744.1
• Gene: Snx13 / 217463
• MGIID: 2661416
• Length: 968
• Species: Mus musculus
• Alignment Length: 1079
• Identity: 245/1079 - (22%)
• Similarity: 402/1079 - (37%)
• Gaps: 286/1079 - (26%)

  Fly    60 LAVIWYYPTFFLFFAFVVYSLVLVFAAVAGTVYIHYIFTTNE-----------PTPPSRVPS--- 110
            |.::.:..||..|..|.:...:|.|......|.:.|..|.:|           |...|.||.
Mouse    15 LGIVLFLITFGPFVIFYLAFYILCFVGGGLVVTLLYGKTNSEKYLEQCEHSFLPPTSSGVPKCLE 79

  Fly   111 ---------RLLYNATKSNIFDLPKPIKNPSNLPLIFGKTVDLQLQQIIEYVLRDFMLPWLGYVV 166
                     ::....|.:||.|.|                    |||:|::.|||::..|. |.:
Mouse    80 EMKREARTIKIDRRLTGANIIDEP--------------------LQQVIQFSLRDYVQYWY-YTL 123

  Fly   167 TKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRIAEARAAETNTPPVF 231
            :..:.....:|:.|.||:.:...|:..:|........:|:....||...|.|:.|..|.: ..|.
Mouse   124 SDDESFLLEIRQTLQNALIQFATRSKEIDWQPYFTTRIVDDFGTHLRVFRKAQQRVTEKD-DQVK 187

  Fly   232 STNSYLADE----EKEME-----------------FLRKLCEIMVILLLPRG-YSLPPLKVLLSE 274
            .|...|.:.    |.|||                 |||.|||:::.||||.| :....::..:.|
Mouse   188 GTAEDLVETFFEVEVEMEKDVCRDLVCTSPKDEEGFLRDLCEVLLYLLLPPGDFQSKIMRYFVRE 252

  Fly   275 ILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNLEELS 339
            ||:..|..|:|..|:.||||||.|:..|.             :...::|.|:.||..|.|:.||.
Mouse   253 ILARGILLPLINQLSDPDYINQYVIWMIR-------------DSNCNYEAFMNIIKLSDNIGELE 304

  Fly   340 LIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLKRY----VRQLTMAKGECEK 400
            .:|..         ..:.||..:.||...:|.:..|:::.:.:.:|:.    :::|...|   |.
Mouse   305 AVRDK---------AAEELQYLRSLDTAGDDINTIKNQINSLLFVKKVCDSRIQRLQSGK---EI 357

  Fly   401 NLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEEIKHAHKSASHQL 465
            |..|..  .|:.....:.|..||...|..::|..:::.....|.:.|::.||..:   .:|..||
Mouse   358 NTVKLA--ANFGKLCTVPLDSILVDNVALQFFMDYMQQTGGQAHLFFWMTVEGYR---VTAQQQL 417

  Fly   466 ------------------------GTEIFYTYIRVPKS-EIQIDKH-ERKLIETFLLGDAEPDIF 504
                                    ...|:..|:....| .:.:|.: ..||.:|....|..|:||
Mouse   418 EVLSGRQRDGKQQTNQTKGLLRAAAVGIYEQYLSEKASPRVTVDDYLVAKLADTLNHEDPTPEIF 482

  Fly   505 YDIQRNV--LRTLEEKYYPPFVLSDQYRQLKEALDSNEIADPTLLMCHTIGDVQEPLADEQPGAA 567
            .||||.|  |...:|::||.|..:..|.::...||.  :.||:             ......|..
Mouse   483 DDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDM--LKDPS-------------FRGSDDGDG 532

  Fly   568 DGLNGGAGGAIDVAAHTSYARRKLEQIQERIDKKNQALDALKYSVKPESKVLTILEKEMEWLKSE 632
            :..||...|:|                       |.:||.|. ||..:..|
Mouse   533 ESFNGSPTGSI-----------------------NLSLDDLS-SVTSDDSV-------------- 559

  Fly   633 KRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINAPVQPTSSKNGDSGH 697
              |..|::..|                               |:.|.|..|    .:....|.|.
Mouse   560 --QLHAYISDT-------------------------------VYADYDPYA----VAGVCNDHGK 587

  Fly   698 A------NLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAI-DLPTNFKFFFLKTDRHGQ 755
            .      .:.:|.......|...|..:..|:...::.....||.:| .||.  |..|...||...
Mouse   588 TYALYAITVHRRNLNTEEMWKTYRRYSDFHDFHMRITEQFENLSSILKLPG--KKTFNNMDRDFL 650

  Fly   756 EKAKSQIQKFLNFILEDDHLNGSEA----IY--------------------TFLSPSSDHLKQSL 796
            ||.|..:..:|..:|..:.:..|.|    :|                    ||::|..:.::...
Mouse   651 EKRKKDLNAYLQLLLTPEMMKASPALAHCVYDFLENKAYSKGKGDFARKMDTFVNPLRNSMRNVS 715

  Fly   797 PSPKKSKFSLS---TLFRSDAGKAHEASKATDPFWGLQRDDEDIS----------TYLDGESGGE 848
            .:.|....||:   |....:.|:..|            |..:||.          |..|  |..|
Mouse   716 NAVKSLPDSLAEGVTKMSDNVGRMSE------------RLGQDIKQSFFKVPPLITKTD--SDPE 766

  Fly   849 AKMLAADLDSK--DSI-AEPMYALMGEIFDMGGVFKWLRKSLISFVQ----ITYGRTINRQIRES 906
            ...::|.||..  |:| ...|..||.|:||:....:|||:::.:.:|    .|||.||||:|.:.
Mouse   767 HCRVSAQLDDNVDDNIPLRVMLLLMDEVFDLKERNQWLRRNIKNLLQQLIRATYGDTINRKIVDH 831

  Fly   907 VAYLFEESMLHNYFSAILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQ 971
            |.::.....:.:.......:|||.|:||...|.|.:.:|..|..|.|..|...:|:.|.:::||:
Mouse   832 VDWMTSPEQVADSVKRFRDAFWPNGILAETVPCRDKAIRMRTRIAGKTKLFAIMPDELKHIIGAE 896

  Fly   972 AAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEIR 1010
            ..::|:|:||:..|:...|:::.|..||..:...||:.:
Mouse   897 TTRKGILRVFEMFQHNQLNRRMVYVFLEGFLETLFPQYK 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	54/179 (30%)
		RGS_SNX25	422..531	CDD:188675	33/136 (24%)
		PX_SNX25	645..788	CDD:132788	29/173 (17%)
		Nexin_C	882..987	CDD:462541	35/108 (32%)
Snx13	NP_001395744.1	PXA	97..284	CDD:470618	59/221 (27%)
		RGS_SNX13	377..511	CDD:188674	33/136 (24%)
		PX_SNX13	557..687	CDD:132783	31/182 (17%)
		Nexin_C	803..911	CDD:462541	34/107 (32%)