Protein Alignment snz and LOC1280336

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_061511713.1
• Gene: LOC1280336 / 1280336
• VectorBaseID: AGAMI1_013586
• Length: 734
• Species: Anopheles gambiae
• Alignment Length: 1040
• Identity: 179/1040 - (17%)
• Similarity: 328/1040 - (31%)
• Gaps: 395/1040 - (37%)

  Fly    40 LLRALQLNWRIIVSGITLTLLAVIWYYPTFFLFFAFVVYSLVLVFAAVAGTVYIH----YIFTTN 100
            ||:..|.:...:::...||:..|.      .|:.::::...:|:|       :||    .:|..|
Mosquito    10 LLKFYQDDIARVIAAAVLTVALVC------TLYVSYIIGLTILLF-------FIHGCAAAVFVLN 61

  Fly   101 EPTPPSRVPSRLL-------YNATKSNIFD---------------LPKP-----IKNPSNLPLIF 138
            ......|...|..       |:|:..:..|               :|||     |:.|
Mosquito    62 HKETFGRYIQRAKDFIGFKDYDASNRHECDVCGNDRCPRHNRNVLVPKPSAGFYIEQP------- 119

  Fly   139 GKTVDLQLQQIIEYVLRDFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVD 203
               :|..:.:...::|..|:..|...|....:.:.. ::..|.:|:.::..||..:||..:|...
Mosquito   120 ---LDDAIDRFFTHILDSFIRSWYNQVTPDEEFLYH-LKSTLRDALCRLVLRAKEIDAPGVIMNR 180

  Fly   204 MVNRVTVHLEKI-------RIAEARAAETNTPPVFSTNSYLADEEKEMEFLRKLCEIMVILLLPR 261
            ::..|.:|.|.|       |:...:.|:|.....:..:..:.:...|:.:||.:.::    |:||
Mosquito   181 LLPTVFIHYEIIAKMLLVDRVPMDKLAKTFVIDEYPIHPAVLNRGAEINYLRGVAKV----LIPR 241

  Fly   262 GYSL--PPLKV---LLSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAAS 321
            .::.  ...|:   |:.|:|::.:..|::.::..|:.||..::         .|..||:.:....
Mosquito   242 LFTAENTSCKIFFNLIKELLTFWVLLPIMDVIADPNLINLLII---------IATDKRAKDGTRK 297

  Fly   322 FEDFLKIINNSGNLEELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRLKR 386
            ..|..|:                           |:.::.|.|| |....||.|.|....
Mosquito   298 VGDAAKV---------------------------QHCEKVKILD-DFVGRSLRKLECGVP----- 329

  Fly   387 YVRQLTMAKGECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAV 451
              |.:|:.:        :..|     .|.|...           ||..||....:..|:.|||.|
Mosquito   330 --RDVTVPQ--------EILW-----EDKDKLY-----------YFMQFLIKEGSVELLQFYLDV 368

  Fly   452 E----EIKHAH-------KSASHQLGTEIFYTYIRVPKS-EIQIDKHERKLIETFLLGDAEPDIF 504
            :    |::..|       .|:.||...::...|..:.|: :.|.|..:...:.|..
Mosquito   369 DNLNKELEDPHITTDPTKLSSLHQQSEKLLQKYQSMVKAVDSQFDGEDTTPVGTLT--------- 424

  Fly   505 YDIQRNVLRTLEEKYYPPFVLSDQYRQLKEALDSNEIADPTLLMCHTIGDVQEPLADEQPGAADG 569
             :....|...||||::..|..:.:|..|  .....||.:|                 .....:||
Mosquito   425 -EAHERVRLKLEEKWFKQFSKTSEYFSL--VYGGREIREP-----------------HDKRGSDG 469

  Fly   570 LNGGAGGAIDVAAHTSYARRKLEQIQERIDKKNQALDALKYSVKPESKVLTILEKEMEWLKSEKR 634
            .:|..                                         :|:.|
Mosquito   470 TSGSG-----------------------------------------TKLST-------------- 479

  Fly   635 QTEAHLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINAPVQPTSSKNGDSGHAN 699
                             |:|..|:..                ||   .||::.|.|.
Mosquito   480 -----------------KFKEVIRGA----------------VD---GAPIEATESP-------- 500

  Fly   700 LRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLK-----AIDLPTNFKFFFLKTDRHGQEKAK 759
                        .|..:||.||........|:..|:     ::|:       |:.|..|..|:
Mosquito   501 ------------TVWDALNDVHPSNNIYNSVTQKLRKEKGQSLDV-------FMSTFMHSIEQ-- 544

  Fly   760 SQIQKFLNFILEDDHLNGSEAIYTFLSP--SSDHLKQSLPSPKKSKFSLSTLFRSDAGKAHEASK 822
                                      ||  ..|.:::..|..||:|....::...|..:..:|||
Mosquito   545 --------------------------SPDIGEDVVQEKEPVKKKTKIPGQSVVFGDLFELKKASK 583

  Fly   823 ATDPFWGLQRDDEDISTYLDGESGGEAKMLAADLDSKDSIAEPMYALMGEIFDMGGVFKWL---- 883
            .|           ..:|.|.....|.::..             :|.|: ::.:...:...|
Mosquito   584 NT-----------HTTTLLSHSVRGPSQCF-------------VYILV-KVLNAPFLIVRLALAF 623

  Fly   884 ----RKSLISFVQITYGRTINRQIRES-VAYLFEESMLHNYFSAILKSFWPGGVLASAYPTRSED 943
                |||:.:.:.....:.|...::|| :|:|.  ::|..:            |.....|..:..
Mosquito   624 CCVSRKSVDTLINSLTAKLIRAGLKESRLAFLI--NLLREH------------VFLRKQPEPTPA 674

  Fly   944 MREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPE 1008
            |.......|:..|.|              .:.|:..:.|.||:|..||.|.|.|.:||:.|.:||
Mosquito   675 MLLKRQQEARKRLED--------------LRGGLGNLADVLQSPVLNKHLMYCLFDILLAEMYPE 725

  Fly  1009  1008
            Mosquito   726  725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	33/169 (20%)
		RGS_SNX25	422..531	CDD:188675	26/120 (22%)
		PX_SNX25	645..788	CDD:132788	23/149 (15%)
		Nexin_C	882..987	CDD:462541	20/113 (18%)
LOC1280336	XP_061511713.1	None