Protein Alignment snz and snz

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_061505781.1
• Gene: snz / 1277426
• VectorBaseID: AGAMI1_014933
• Length: 1161
• Species: Anopheles gambiae
• Alignment Length: 1181
• Identity: 540/1181 - (45%)
• Similarity: 716/1181 - (60%)
• Gaps: 174/1181 - (14%)

  Fly    52 VSGITLTLLAVIWYYPTFFLFFAFVVYSLVLVFAAVAGTVYIHYIFTTNEPTPPSRV------PS 110
            :..|...|.||..|.|.|..|..||:|||||:..||.||:|:||..|..||.  |.|      .:
Mosquito     7 IGAIAAVLCAVCVYSPIFLYFLLFVLYSLVLIAVAVFGTIYVHYKLTNREPV--SYVDQGEDQQA 69

  Fly   111 RLLYNATKSNIFDLPKPIKNPS-----------------------NLPLIFGKTVDLQLQQIIEY 152
            .:|||||:|.:|....|..:|.                       .||:|||:|||..|||||:.
Mosquito    70 NVLYNATRSPLFGNGTPGSSPGISRHQGGRSAGGTGGSTGGSGQPQLPIIFGRTVDGLLQQIIDN 134

  Fly   153 VLRDFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRI 217
            .:||.:.|.|..||..|:.|.:::|||:|.:|:|:||||.|:||.|:||.|.|.:||:||:|||.
Mosquito   135 AMRDLVGPALELVVANPRRIVELLREDIWLSIEKLHERAARIDAPKLIACDFVAKVTLHLQKIRR 199

  Fly   218 AEARAAETNT--------------PPVFSTNSYLADEEKEMEFLRKLCEIMVILLLPRGYSLPPL 268
            ..|.||...|              .||. |.||||..|||::||:|:.||:||.||||||||.|:
Mosquito   200 QTAAAANGGTKREGGPAEATGEQADPVV-TASYLASTEKELDFLKKIGEILVIFLLPRGYSLSPV 263

  Fly   269 KVLLSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSG 333
            |.||||:|:|::..|.|..|||||:|||::|:.|||||.|.|:.|||:||||:|||||:||:.:.
Mosquito   264 KDLLSEVLAYRVLHPAIHYLTAPDFINQQIVECIETRLVAVAIQKRSHEYAANFEDFLRIIDMTQ 328

  Fly   334 NLEELSLIRKSIVNDLMHATTMQNLQRAK-------------GLDPDHEDHSLSKSELTAAV-RL 384
            .:|||..||.|||:|:..||.||.:||.:             |...|:...|....|..||. ||
Mosquito   329 TVEELQSIRASIVSDIRQATAMQTMQRTRGGFAMAACDGADTGGSADNGGASGGDGEPAAATQRL 393

  Fly   385 KRYVRQLTMAKGECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYL 449
            |||::||:.||.:||:.||:.||.|..|:|:||:|.:||:|..|||..|.|||||.|::|:|:|.
Mosquito   394 KRYIQQLSYAKSQCEQCLARLGWEGCVSNDVDLSLADILSTVGGRRALTAFLEPLNAASLVGYYT 458

  Fly   450 AVEEIKHAHKSASHQLGTEIFYTYIRVPKSEIQIDKHERKLIETFLLGD-AEPDIFYDIQRNVLR 513
            .|||::.|.:||.||||.||||||:|.|.|||.:||..||.:|.||:|| ..||:||::||..|.
Mosquito   459 TVEELRRAARSAWHQLGAEIFYTYVRAPSSEIPLDKATRKRMEAFLVGDVGGPDVFYEVQRECLA 523

  Fly   514 TLEEKYYPPFVLSDQYRQLKEALDSNEI-------------------ADPTLLMCH-TIGDVQEP 558
            .||:|||.||:|||:|.:||.:|..:|.                   .:..|::.| |..|.||.
Mosquito   524 LLEQKYYRPFLLSDEYGRLKRSLTQDEFKELIASSGTSGVSGGGCGGLENELMLQHATSQDSQES 588

  Fly   559 LADEQPGAADGLNGGAGGAIDVAA-----HTSYARRKLEQIQERIDKKNQALDALKYSVKPESKV 618
            ........|:|  ||..||.|.|.     |:.|||.||:::.|::..|.|||:|||.|:||:||:
Mosquito   589 QESSTGSTANG--GGGEGATDPALADLSNHSQYARNKLDRLDEKLANKQQALEALKQSLKPDSKL 651

  Fly   619 LTILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINA 683
            |.:||:|:|||:.|:||.|:||.||..|.|:||.|:|.::||:.||::|..||||:|.||| :|.
Mosquito   652 LLMLEREIEWLRGERRQLESHLLRTAVWGEYLGSWRAIVESVDFSDDREPPQFMIVVQVDE-MND 715

  Fly   684 PVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAIDLPTN--FKFF 746
            .....|....|:......:....||:||||:|||.|.|.|.||||.:...|:.:|||:|  ||.|
Mosquito   716 YGSGGSGGRDDTTVTTALEATDTISTGWVVVRSLTQFHALHRKLRPMCVELRQLDLPSNNAFKLF 780

  Fly   747 FLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSPSSDHLKQSL----PSPKK---SKF 804
            .||.||...||||:|:|::|:|||||||||.|||:|.|||||||.|||.:    |||.|   |||
Mosquito   781 LLKNDRALLEKAKAQVQRYLSFILEDDHLNQSEAVYEFLSPSSDRLKQGVLTGNPSPSKKQTSKF 845

  Fly   805 SLSTLFRSDAGKAHE--------ASKATDPFWG------------LQRDDEDISTYLDG------ 843
            ||:|:|||::.|..:        .:....||..            ...|.:.:|.||:|
Mosquito   846 SLATIFRSNSDKLEQLWHVGSGGGAGGERPFGSGGGGGTDHHPDFTPEDADQVSLYLEGGPAPSG 910

  Fly   844 --ESGGEAKM--LAADLDSKDSIAEPMYALMGEIFDMGGVFKWLRKSLISFVQITYGRTINRQIR 904
              .||.....  .|..::.:||||||:|.|:|||||:||||:|||||||||||||||:|||||:|
Mosquito   911 PSSSGASPPTDGAAVAMELRDSIAEPLYGLLGEIFDLGGVFRWLRKSLISFVQITYGQTINRQLR 975

  Fly   905 ESVAYLFEESMLHNYFSAILKSFWPGG---------VLASAYPTRSEDMREMTTTAAKALLTDHI 960
            ||:|.||:|.|||.|.||:|:|.||||         :|.||  .|:||.|||...||::||.|:|
Mosquito   976 ESIAALFDEPMLHAYASAVLRSLWPGGGTLQADGVRLLPSA--ERTEDEREMIMNAARSLLQDNI 1038

  Fly   961 PEVLCNLVGAQAAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEIRQLRVSNSNGTKLNTA 1025
            ||:||:|:|||.|::|.||:|:.|||..|||||||:|||.||:|.|||||||:
Mosquito  1039 PELLCSLIGAQNARQGALKLFEVLQNSLYNKQLFYDLLETLMLELFPEIRQLK------------ 1091

  Fly  1026 TAGAAAASAAAALVAATASASLPSLNHSGGGHSAST---GGHQNHQGSSSASGSSAGA------- 1080
             ..||.::...|.||.         .|:.|..|:||   ....:||  .:|:|||..|
Mosquito  1092 -PAAAGSTGNCATVAP---------GHATGSSSSSTVLRPREYHHQ--PAAAGSSPAAPIYSPPT 1144

  Fly  1081 -SGATGGGAAS 1090
             :||.|..:.:
Mosquito  1145 PTGAVGSASGT 1155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	87/171 (51%)
		RGS_SNX25	422..531	CDD:188675	64/109 (59%)
		PX_SNX25	645..788	CDD:132788	73/144 (51%)
		Nexin_C	882..987	CDD:462541	69/113 (61%)
snz	XP_061505781.1	None