Protein Alignment snz and Snx19

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_030099808.1
• Gene: Snx19 / 102607
• MGIID: 1921581
• Length: 998
• Species: Mus musculus
• Alignment Length: 1077
• Identity: 200/1077 - (18%)
• Similarity: 351/1077 - (32%)
• Gaps: 344/1077 - (31%)

  Fly   140 KTVDLQLQQIIEYVLRDFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDM 204
            :.::.::.:.|:.::|||:|.|...|..:|....: :...:...:|::..|...:|:..     :
Mouse    96 RQLEQEINRTIQMIIRDFVLSWYRSVSHEPAFEAE-MEAAMKGLVQELRRRMSIVDSHA-----L 154

  Fly   205 VNRVTV----HLEK-IRIAEARAAETNTP-----------PVFSTNSYLADEEKEMEFLRKLCEI 253
            ..||..    ||:. |:..||.|.|.:.|           .|.:.:..::....|:.:.|.:..:
Mouse   155 TQRVLTLCGCHLQSYIQAKEATAKEQSCPVQPSQLWDAYCQVTAPHPAMSCPTTEVTYARGIVNL 219

  Fly   254 MVILLLPRGYSLPPLKV-----LLSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSK 313
            ::..|:|:    |.|:.     ::.|:::..:..|:|..|:.||:|:..:|         :..||
Mouse   220 ILKELVPK----PHLETRTGRHVVVEVITCNVILPLISKLSDPDWIHLILV---------SIFSK 271

  Fly   314 RSYEYAASFEDFLKIINNSGNLEELSLIRKSIVNDLMHATTMQNLQRAKGLDPD----------- 367
            ..::.|..    .|...:|..||:     .|:...|.....:::|...|...|.
Mouse   272 YRHDAAQG----TKPPCSSSVLEQ-----PSVPTSLPLIVEVESLPVGKASSPATAPVHLTSSEP 327

  Fly   368 ------HEDHSLSKSELTAAVRLKRY-----------VR---------QLTMAKGECEKNLAKFG 406
                  .|.|...:.:|...:..|:.           :|         :|.....|..|......
Mouse   328 APSPEIEEGHEAVEGDLPGMLEEKKVGNSSSHFLQPDIRGPLFLCEDSELESPLSELSKETILLM 392

  Fly   407 WNGNYSSD-IDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEEIKHAHKSASHQLGTEIF 470
            ..||:.|| |...|..:.::..        |||..     |......|...|.::......|.:.
Mouse   393 TPGNFLSDRIQDALCALDDSGA--------LEPKD-----GEGSECMEGAEAEEAPGTDTETGML 444

  Fly   471 YTYIRVPKSEIQIDKHERKLIETFLLGDAEPDIFYDIQRNVLRTLEEKYYP-PFVLSDQYRQLKE 534
            .:.:..|  |||||..::::.:    ||         ..::...|||...| |...|...:.|..
Mouse   445 VSVLNCP--EIQIDTADKEVEQ----GD---------DTSLTALLEEPEKPCPLRPSCLDKDLAS 494

  Fly   535 ALDSNEIADPTLLMCHTIGDVQEPLADEQPGAADGLNGGAGGAIDVAAHTSYARRKLEQIQERID 599
            .:.|.|.|.|.:           ||:...||.                 .|.|....|.:.
Mouse   495 GVCSLEPAMPPV-----------PLSSSPPGP-----------------LSSATFSFESLS---- 527

  Fly   600 KKNQALDALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDAWT--EHLGK-------WKA 655
                         .|:..|:.                 .:||.|...|  ||.|.       :..
Mouse   528 -------------SPDGPVVI-----------------QNLRITGTITAREHSGTGFHPYTLYTV 562

  Fly   656 TIQSVEVSDEKESLQFMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQV 720
            ..::|...:....|| .:..|.   :|...:.         ..||:.|             |.:.
Mouse   563 KYETVLNGENSSGLQ-QLAYHT---VNRRYRE---------FLNLQTR-------------LEEK 601

  Fly   721 HELQRKLRHVSSNLKAI-DLPTNFKFFFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTF 784
            .:|::.:::|....|.. |||    |..:.:||  .|..||.::.||..:.....:..||.:..|
Mouse   602 PDLRKFIKNVKGPKKLFPDLP----FGNMDSDR--VEARKSLLESFLKQLCAIPEIGNSEEVQEF 660

  Fly   785 LSPSSDHLKQSLPSPKKSKFSLSTLFRSDAGKAHEASKATDPFWGLQRDD--------------- 834
            |:.::|.....:..|    |.:|   |.|..|| .|.:...|....||||
Mouse   661 LALNTDARIAFVKKP----FMVS---RIDKAKA-LAGELFSPSAKAQRDDCPALYHCPSGTCKTV 717

  Fly   835 ------------------------------EDISTYLDGESGGEAKMLA---------------- 853
                                          :|...|...|...|:::|:
Mouse   718 LILYLQPCRWWSRLRFSSSKIAPALSIAEAQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLR 782

  Fly   854 ---ADLDSKDSIAEPMYALMGEIFDMGGV------------------------------FKWL-R 884
               |::..||....|...:...:.|...|                              :||| .
Mouse   783 IQPAEVPDKDPQQVPKEYVDSGLLDKAVVAQELNKSGPGTETELADTAFDLILLLLMEQWKWLCT 847

  Fly   885 KSLISFVQITYGRTINRQIRESVAYLFEESMLHNYFSAILKSFWPGGVLAS-AYPTRSEDMREMT 948
            :|:..|:.|.:|..:.|.:...||.|........|...:.:|.||||||.. ..|.|::..:..|
Mouse   848 ESMQKFLHIIFGTLVQRWLEVQVANLTCPQRWAQYLHLLRESIWPGGVLPKFPRPGRTQAQKAAT 912

  Fly   949 TTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEIRQLR 1013
            ...|...|.|.:|:.|..::|....:.....|.::.|.|..|:.|.|.|.:|::     |:..|
Mouse   913 EKQALQSLMDLLPDFLVEILGVNKCRLSWSLVLESFQQPLINRHLIYCLGDIIL-----ELLDL- 971

  Fly  1014 VSNSNGTKLNTATAGAAAASAAAALVAATASASLPSL 1050
                          .|:....|.|..|:.:..||..:
Mouse   972 --------------SASVEECAPATSASDSPGSLKKM 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	35/178 (20%)
		RGS_SNX25	422..531	CDD:188675	21/109 (19%)
		PX_SNX25	645..788	CDD:132788	31/152 (20%)
		Nexin_C	882..987	CDD:462541	29/106 (27%)
Snx19	XP_030099808.1	PXA	95..273	CDD:214611	38/195 (19%)
		PX_SNX19	537..664	CDD:132803	34/158 (22%)
		Nexin_C	844..951	CDD:462541	29/106 (27%)