Protein Alignment snz and snx13

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_002933347.2
• Gene: snx13 / 100495358
• XenbaseID: XB-GENE-6037458
• Length: 975
• Species: Xenopus tropicalis
• Alignment Length: 1083
• Identity: 249/1083 - (22%)
• Similarity: 429/1083 - (39%)
• Gaps: 235/1083 - (21%)

  Fly    21 IEPEPSVTATQRLTLLATRLLRALQLNWRIIVSGITLTLLA----VIWYYPTFFLFFAFVVYSLV 81
            |..||.:....|...:...:|:|....|.....|:.|.|:.    .|:|:..:.|.|....:.:.
 Frog     2 IPKEPCLDERNRKEDVVNCILKASLSVWGWGSLGVVLFLIKFGPFAIFYFAFYILCFVGGGFVVT 66

  Fly    82 LVFAAVAGTVYIHYIFTTNEPTPPSRVPSRLLYNATKSNIFDLPKPIKNPSNLPLIFGKT-VDLQ 145
            ::|...:...|:.....:..|:..:.:|..|      ..|...|:.||....   |.|.: :|..
 Frog    67 ILFGKTSSERYLERCEHSFLPSTSTGIPKCL------EEIKREPRTIKIDRR---ITGASMIDEP 122

  Fly   146 LQQIIEYVLRDFMLPWLGYVVTKPKLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTV 210
            |||:|::.|||::..|. |.:::.:.....:|:.:.||:.:...|:..:|........:|:....
 Frog   123 LQQVIQFSLRDYVQYWY-YTLSEDESFLLEIRQTVQNALVQFSTRSKEIDWQPYFTTRLVDDFAT 186

  Fly   211 HLEKIRIAEARAAETNTPPVFSTNSYL---ADEEKEME-----------------FLRKLCEIMV 255
            ||...|.|:.:.||...........::   .:.|.|||                 .|:.|||:::
 Frog   187 HLRVFRKAQQKMAEKEDQKKDKAEDFIDTFFEVEVEMEKCVCRDLVCTSSKDEEGCLKDLCEVLL 251

  Fly   256 ILLLPRG-YSLPPLKVLLSEILSYKIFFPMIKMLTAPDYINQKVVQNIETRLAAAAMSKRSYEYA 319
            .||||.| :....::..:.||||..|..|:|..|:.||||||.::..|             ::::
 Frog   252 YLLLPPGDFQNKIMRYFVREILSRGILLPLINQLSDPDYINQYIIWMI-------------HDFS 303

  Fly   320 ASFEDFLKIINNSGNLEELSLIRKSIVNDLMHATTMQNLQRAKGLDPDHEDHSLSKSELTAAVRL 384
            .::|.|:.:|..|||:.||..:|..         ..:.||..:.||...:|.:..|:::.:.:.:
 Frog   304 CNYEAFMNVIKLSGNISELEAVRDK---------AAEELQYLRSLDTVGDDINTIKNQINSLLFV 359

  Fly   385 KRYVRQLTMAKGECEKNLAKFGWNGNYSSDIDLTLVEILNTAVGRRYFTLFLEPLKASALIGFYL 449
            |: |.:..:.:.:..|.:.......|:.....:.|.:||...|..::|..|::.....|.:.|:|
 Frog   360 KK-VCETRIQRLQSGKEIDTVKLAANFGKLCTVPLDKILVDNVALQFFMDFMQQTGGQAHLFFWL 423

  Fly   450 AVE----------EIKHA-HKSASHQLGTE----------IFYTYIRVPKS-EIQIDKH-ERKLI 491
            .||          |:.|: .:...||....          ::..|:....| .:.||.: ..||.
 Frog   424 TVEGYRVTAQQQLEVLHSRQRDGKHQTNQTKGLLKAAAFGVYEQYLSEKASPRVHIDDYLLAKLE 488

  Fly   492 ETFLLGDAEPDIFYDIQRNV--LRTLEEKYYPPFVLSDQYRQLKEALDSNEIADPTLLMCHTIGD 554
            |.....|..|:||.||||.|  :....|::||.|..:..|.::...||.
 Frog   489 EKLNSEDPTPEIFDDIQRKVYDMMLRNERFYPSFRQNTLYIRMLAELDM---------------- 537

  Fly   555 VQEP-LADEQPGAADGLNGGAGGAIDVAAHTSYARRKLEQIQERIDKKNQALDALKYSVKPESKV 618
            ::|| ......|..:..||...|:|    |:|                   ||.|..|
 Frog   538 LKEPSFKGSDDGDGESFNGSPNGSI----HSS-------------------LDDLTSS------- 572

  Fly   619 LTILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDEKESLQFMILVHVDEDINA 683
                        .|..|..|.:..|....|| ||   |.....::.::.:|..|      ||:
 Frog   573 ------------DELLQINAFISDTGVCNEH-GK---TYALYAITVQRRALDSM------EDM-- 613

  Fly   684 PVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKA-IDLPTNFKFFF 747
                                       |...|..:..|:...::.....||.: :.||.  |..|
 Frog   614 ---------------------------WKTYRRYSDFHDFHMRITEQFENLASLLKLPG--KKTF 649

  Fly   748 LKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAI--YTFLSPSSDHLKQSLPSPKKSKFS----- 805
            ...|:...||.::.:..:|..:|..:.:..|.|:  |.|     |.|:....|..|..|:
 Frog   650 NNMDKEFLEKRRNDLNAYLQLLLNPEIVKASPALAHYVF-----DFLENKAYSKGKGDFARKMDT 709

  Fly   806 ----LSTLFR--SDAGKAHEASKATDPFWGLQRDDEDISTYLDGESGGEAK-------------- 850
                |....|  |:|.|:...|.|.    |:.:..:::.. :..:.|.:.|
 Frog   710 FVNPLRNSMRNVSNAVKSIPDSLAE----GMNKMSDNMGK-MSEKIGQDIKHSFFKAPILVPKTD 769

  Fly   851 ------MLAADLDSK--DSI-AEPMYALMGEIFDMGGVFKWLRKSLISFVQ----ITYGRTINRQ 902
                  .::|.||..  |:| ...|..||.|:||:....:|||:.:.|.:|    .|||.||||:
 Frog   770 AFPENYRVSAQLDDNVDDNIPLRVMLLLMDEVFDLKERNQWLRRQITSLLQQLIRATYGDTINRK 834

  Fly   903 IRESVAYLFEESMLHNYFSAILKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNL 967
            |.:.|.|:.....:.:|.....:||||.|:||.|...|...:|..|..|||..|.:.:|:.|.::
 Frog   835 IVDHVQYMTSPDQVADYVKQFRESFWPNGILAEASLRRDRSIRMRTRVAAKTKLLEIMPDELKHI 899

  Fly   968 VGAQAAKRGVLKVFDALQNPAYNKQLFYELLEILMIEFFPEIR 1010
            :||:..::|:|:||:..|....|::|.|..||..:...||:.:
 Frog   900 IGAETTRKGILRVFEMFQYNQLNRRLVYVFLEGFLETLFPQYK 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	49/178 (28%)
		RGS_SNX25	422..531	CDD:188675	35/133 (26%)
		PX_SNX25	645..788	CDD:132788	27/145 (19%)
		Nexin_C	882..987	CDD:462541	40/108 (37%)
snx13	XP_002933347.2	PXA	119..301	CDD:470618	50/195 (26%)
		RGS_SNX13	396..530	CDD:188674	35/133 (26%)
		PX_SNX13	576..694	CDD:132783	32/163 (20%)
		Nexin_C	810..918	CDD:462541	39/107 (36%)