Protein Alignment snz and snx25

DIOPT Version :10

• Sequence 1: NP_572421.1
• Gene: snz / 31704
• FlyBaseID: FBgn0029976
• Length: 1117
• Species: Drosophila melanogaster
• Sequence 2: XP_004911239.1
• Gene: snx25 / 100127563
• XenbaseID: XB-GENE-1001658
• Length: 1046
• Species: Xenopus tropicalis
• Alignment Length: 1005
• Identity: 317/1005 - (31%)
• Similarity: 529/1005 - (52%)
• Gaps: 107/1005 - (10%)

  Fly    51 IVSGITLTLLAVIWYY---------PTFFLFFAFVVYSLVLVFAAVAGTVYIHYIFTTNEPTPPS 106
            ::..:.:.||||..::         |...|.|..::....:..|...|.:.:......:....|:
 Frog   112 LILAVVICLLAVSLFHLAQGIGQPSPAGELCFTVLLLRCFVYLACALGALILGAFCVLHRTGRPT 176

  Fly   107 RVPSRLLYNATKSNIFDLPKPIKNPSNLP--LIFGKTVDLQLQQIIEYVLRDFMLPWLGYVVTKP 169
            .:|.......|..::  ||:.:..|.. |  ::....:|..|:::.:|..||::|.|.|.:....
 Frog   177 ALPDFTRAARTTGSL--LPRIVHEPVQ-PRRVVISHNMDKALKEVFDYSYRDYILSWYGDLTKDD 238

  Fly   170 KLINDVVREDLWNAIQKIHERALRMDAAKIIAVDMVNRVTVHLEKIRIAEARAAETNTPPVFSTN 234
            ..:...:.:|.|...:::..|...:|..:::..|:|..:..|..:::.|.:|..|  .|.:|:.:
 Frog   239 GQLYHFLSDDFWELARQLRSRLTHIDVVRVVCNDVVKNLLAHFCELKAASSRQDE--QPRLFALH 301

  Fly   235 SYLADEEKEMEFLRKLCEIMVILLLP-RGYSLPPLKVLLSEILSYKIFFPMIKMLTAPDYINQKV 298
            ..|.:.|:|::||:...:::|:.||| |......|:::|||||:.|:..|::::|:.||||||.:
 Frog   302 PCLKNSEEEVKFLQSCAQVLVLCLLPTRDARSRCLRIVLSEILATKVLKPLVELLSDPDYINQML 366

  Fly   299 VQNIETRLAAAAMSKRSYEYAASFEDFLKIINNSGNLEELSLIRKSIVNDLMHATTMQNL-QRAK 362
            :..:|.|.......|::|.||.|:|:|:|:|.:|.::|.|..:|..||.:::.|||:.:. |..:
 Frog   367 LSQLEYREQVNERHKKAYTYAPSYEEFIKLITSSSDVEFLKQLRYQIVVEIIQATTIGSFPQMKR 431

  Fly   363 GLDPDHEDHSLSKSELTAAVRLKRYVRQLTMAKGECEKNLAKFGWNGNYSSD---ID-------- 416
            ..||..::.:..|::|..|..:|||:.|||:||.:|||.:...|.......|   :|
 Frog   432 QKDPKGKETAAMKADLLRARNMKRYINQLTVAKKQCEKRIKLLGGPAYDQQDDGAVDDSECPQSQ 496

  Fly   417 --LTLVEILNTAVGRRYFTLFLEPLKASALIGFYLAVEEIKHAHKSASHQLGTEIFYTYIRVPKS 479
              |...|||.....|..|.|::|.:...|||.|:.:||.:|:|:|:...||..||:..|. |...
 Frog   497 KILQFDEILANPSFREQFRLYMERIDKRALISFWESVEYLKNANKTEIPQLVGEIYQNYF-VESK 560

  Fly   480 EIQIDKHERKLIETFLLGDAEPDIFYDIQRNVLRTLEEKYYPPFVLSDQYRQLKEALDSNEIADP 544
            :|.::|...|.|:..|:|:...::|..||.:|..||:::|||.|::||.|.:|....|:
 Frog   561 DIPVEKPLYKEIQQSLVGNKGTEVFNKIQADVYETLKDRYYPSFIVSDLYDRLIRKEDN------ 619

  Fly   545 TLLMCHTIGDVQEPLADEQPG--AADG-------LNGGAGGAIDVAAHTSYARRKLEQIQERIDK 600
              :.|..:.|      |::.|  |.:|       .|||      :....|||..||:|:.:|:|.
 Frog   620 --VSCSCVTD------DKEDGMQACEGNEEILDECNGG------ITEQASYAVNKLQQLTDRLDY 670

  Fly   601 KNQALDALKYSVKPESKVLTILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGKWKATIQSVEVSDE 665
            |.|||:::..:.||:.|:::.|::|:..::.|:...:.|:.|||.|.|:||.|:|.|.:.:||:|
 Frog   671 KRQALNSIINAPKPDKKIISKLKEEIALMEKEQSDLDLHISRTDLWCENLGMWRAVINTSQVSEE 735

  Fly   666 KESLQFMILVHVDEDINAPVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLRHV 730
            .........|    .:|.|         |||.:..|        .|:|.|.|::...|.|||...
 Frog   736 NGEQMPSYTV----SVNLP---------DSGESENR--------NWIVHRKLSEFQNLHRKLSEC 779

  Fly   731 SSNLKAIDLPTNFKFFFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSPSSDHLKQS 795
            ..:||.:.||:..|..|...|:...||:|:|:..||..:|.|:.|..||.:|.|||||.:|||..
 Frog   780 FPSLKKVQLPSLSKLPFKSIDQKFLEKSKTQLNHFLQNLLTDERLYQSEVLYAFLSPSPEHLKAI 844

  Fly   796 LPSPKKSKFSLSTLFRSDAGK--AHEASKATDPFWGLQRDDEDISTYLDGESGGEAKMLAADLDS 858
            ....|||.||:|:......|.  :|:..:.        .:|.|:|.|.|...|           .
 Frog   845 DIQGKKSSFSISSFLERFPGDLFSHQEDET--------EEDSDLSDYGDDVDG-----------K 890

  Fly   859 KDSIAEPMYALMGEIFDMGGVFKWLRKSLISFVQITYGRTINRQIRESVAYLFEESMLHNYFSAI 923
            ||::|||.:.|:.|||::.|:|||:||:||:.||||:|||||:|||::|.::|.|.||..|.:..
 Frog   891 KDALAEPCFMLIVEIFELRGMFKWVRKTLIALVQITFGRTINKQIRDTVNWIFSEQMLVYYINVF 955

  Fly   924 LKSFWPGGVLASAYPTRSEDMREMTTTAAKALLTDHIPEVLCNLVGAQAAKRGVLKVFDALQNPA 988
            ..:|||.|.||.:..:|:|...:.|...|:..|.::||:.|.||||.|.|:.|::|||:|||...
 Frog   956 RDAFWPNGKLAPSKTSRTELQCQETKQRAQQKLLENIPDALQNLVGQQNARHGIIKVFNALQENR 1020

  Fly   989 YNKQLFYELLEILMIEFFPEIRQLRVSNSN 1018
            .||.|.|.::|:|::|..||:|    |.||
 Frog  1021 ANKHLLYVMMELLLVELCPEVR----SQSN 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
snz	NP_572421.1	PXA	142..300	CDD:460484	45/158 (28%)
		RGS_SNX25	422..531	CDD:188675	40/108 (37%)
		PX_SNX25	645..788	CDD:132788	47/142 (33%)
		Nexin_C	882..987	CDD:462541	50/104 (48%)
snx25	XP_004911239.1	PXA	212..368	CDD:460484	45/157 (29%)
		RGS	504..612	CDD:470619	40/108 (37%)
		PX_SNX25	715..837	CDD:132788	47/142 (33%)
		Nexin_C	914..1020	CDD:462541	50/105 (48%)