Protein Alignment Ir7c and grin2aa

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_021329529.1
• Gene: grin2aa / 563297
• ZFINID: ZDB-GENE-070424-129
• Length: 1460
• Species: Danio rerio
• Alignment Length: 484
• Identity: 101/484 - (20%)
• Similarity: 190/484 - (39%)
• Gaps: 84/484 - (17%)

  Fly   199 LTKPLFPRKLTNMHG------CEMVVATFEHRPYVIIED--------------------DPKTPG 237
            |..|::||  .|..|      ..:.:.|.|.:|:||:|:                    |..|.|
Zfish   382 LKYPVWPR--FNSFGDAETDDNHLTIVTLEEKPFVIVENVERLTGTCMRNSVPCRKHIKDNTTEG 444

  Fly   238 G-----RSIHGIEGLIFRSLAERMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVC 297
            |     :...|....|.:.:|..:.||..|....:...|:.: :..:.|::..:|:.:..:....
Zfish   445 GGTYIKKCCKGFCIDILKKIARNVKFTYDLYLVTNGKHGKKI-NNVWNGMVGEVVNKKAVMAVGS 508

  Fly   298 FMYSKARSDLMLPSTSYTSFPI-VLVVPSGGSISPMGRLTRPFRYIIWSCILVSLIF--GFVLIC 359
            ...::.||:::..|..:....| |:|..|.|::||...| .||...:|..:.|.|:.  ...:..
Zfish   509 LTINEERSEVIDFSVPFVETGISVMVSRSNGTVSPSAFL-EPFSASVWVMMFVMLLLVTAMAVFM 572

  Fly   360 LLKITALPGLRNLVLGRRNRLP--FMGMWASLLGGLA------LYNPQRNFARYILVMWLLQTLI 416
            ...|:.|...|||..|:....|  .||....||.||.      :.||:...:::|:.:|....:|
Zfish   573 FEYISPLGFNRNLAQGKDPHGPSFTMGKAVWLLWGLVFNNSVPVQNPKGTTSKFIVSVWAFFAVI 637

  Fly   417 LRAAYTGQLYLLLQDVEMRSPIKSLSE-------VLAKDYEFRILP---ALRTIFKDSMPTTNFH 471
            ..|:||..|...:...|....:..||:       ..:..:.|..:|   ..|.|.| :.|..:.:
Zfish   638 FLASYTANLAAFMIQEEFVDQVTGLSDKKFQSPYSYSPPFRFGTVPNGSTERNIRK-NYPDMHQY 701

  Fly   472 AVLSLEESLYRLRDEDDPGITVALLQPTVNQFD----------FRSGPNK--RHLTVLPDPLM-T 523
            .|           .....|:..||:.....:.|          :.:|.::  :.:|:....:. |
Zfish   702 MV-----------KYHQTGVNDALVSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFAT 755

  Fly   524 APLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNLEPKPLSIWRLSGIFV 588
            ......::..|.:||.:|..|:|::..|.:......::..|.. :::..:....|.:..::|:|.
Zfish   756 TGYGIALQKGSLWKRPVDLAILAIIGDGEMEELEAQWLTGICH-NEKNEVMSSQLDVDNMAGVFY 819

  Fly   589 CCAGLYLVALIVFILEILTTNHRRLRRAF 617
            ..|....::||.|:.|.|.  :.|||..|
Zfish   820 MLATAMGLSLITFVWEHLF--YWRLRYCF 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	16/86 (19%)
		Lig_chan	343..592	CDD:459656	53/281 (19%)
grin2aa	XP_021329529.1	PBP1_iGluR_NMDA_NR2	33..384	CDD:380601	1/1 (100%)
		PBP2_iGluR_NMDA_Nr2	400..799	CDD:270436	82/413 (20%)
		NMDAR2_C	836..1460	CDD:463148	5/13 (38%)