Protein Alignment Ir7c and gria1b

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_991293.1
• Gene: gria1b / 403044
• ZFINID: ZDB-GENE-020125-2
• Length: 917
• Species: Danio rerio
• Alignment Length: 550
• Identity: 101/550 - (18%)
• Similarity: 200/550 - (36%)
• Gaps: 133/550 - (24%)

  Fly   162 TVHLYTYYPYGPHHCQSSLPVYYTAFQDLAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPY 226
            ||.:..:.|.||....     |:...:...:.|....:....|     .:.....||.|....||
Zfish   363 TVSVMEFGPSGPKKVG-----YWNQREKYVSTATYSNMLNETF-----GLQNRTYVVTTILEAPY 417

  Fly   227 VIIEDDPKTPGGRSIHGIEGL---IFRSLAERMNFTIKLVEQKDKNRGEILPDGNF--------- 279
            |:::.:.:...|...:  ||.   :...:|:.:.::.:|         |::.||.:
Zfish   418 VMLKKNHEQLVGNDKY--EGYCVELAAEIAKHVGYSYRL---------ELVGDGKYGARDAETMM 471

  Fly   280 -TGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISP-MGRLTRPFRYI 342
             .|::..:|.|:.::.......:..|.:::..|..:.|..|.:::.......| :.....|..|.
Zfish   472 WNGMVGELVYGKADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSKPGVFSFLDPLAYE 536

  Fly   343 IWSCILVSLIFGFVLICLLKITALP------------------------------GLRNLVLGRR 377
            ||.||:.:.| |..::..|.....|                              ..:|....::
Zfish   537 IWMCIVFAYI-GVSVVLFLVSRFSPYEWHADDEEETADQQNQNQPPSPEPNQSPNQSQNQREEKQ 600

  Fly   378 NRLP--------FMGMWASLLGGLAL-----YNPQRNFARYILVMWLLQTLILRAAYTGQLYLLL 429
            .:.|        |..:|.||  |..:     .:|:....|.:..:|...|||:.::||..|...|
Zfish   601 EKQPEHTNEFGIFNSLWFSL--GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFL 663

  Fly   430 QDVEMRSPIKSLSEVLAKDYE--------------FR-----ILPALRTIFKDSMPTTNFHAVLS 475
            ....|.|||:| :|.|||..|              ||     :...:.:..|.:.||.   .|.:
Zfish   664 TVERMVSPIES-AEDLAKQTEIAYGTLDGGSTKEFFRRSKIAVFEKMWSYMKSAEPTV---FVKT 724

  Fly   476 LEESLYRLRDEDDPGITVALLQPTVNQFDFRSGP-----------NKRHLTVLPDPLMTAPLTFY 529
            .:|.:.|:|  ...|....||:.|:|::..:..|           :|.:....|
Zfish   725 TDEGVVRVR--KSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATP----------- 776

  Fly   530 MRPHSYFKRRIDRLIMAMMSSGIVARYR-KMYMDRIKRVSKRRNLEPK--PLSIWRLSGIFVCCA 591
              ..|..:..::..::.:...|::.:.: |.:.|:.:..|...:.:.|  .||:..::|:|....
Zfish   777 --KGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILI 839

  Fly   592 GLYLVALIVFILEILTTNHRRLRRAFNVIN 621
            |...:|::|.::|....:....||...:|:
Zfish   840 GGLGLAMLVALVEFCYKSRIESRRMKQIID 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	12/74 (16%)
		Lig_chan	343..592	CDD:459656	62/324 (19%)
gria1b	NP_991293.1	PBP1_iGluR_AMPA_GluR1	26..390	CDD:380613	6/31 (19%)
		PBP2_iGluR_AMPA_GluR1	404..812	CDD:270447	80/440 (18%)