Protein Alignment Ir7c and gria3b

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_938174.1
• Gene: gria3b / 368416
• ZFINID: ZDB-GENE-030616-53
• Length: 883
• Species: Danio rerio
• Alignment Length: 539
• Identity: 97/539 - (17%)
• Similarity: 188/539 - (34%)
• Gaps: 150/539 - (27%)

  Fly   162 TVHLYTYYPYGPHHCQSSLPVYYTAFQDLAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPY 226
            |:.:|.....||....     |:..|:...      .:....|....:::....:||.|....||
Zfish   372 TIDVYEMKTGGPRKIG-----YWNEFERFV------NIMDQQFTNDSSSVENRTIVVTTIMEAPY 425

  Fly   227 VI-------IEDDPKTPGGRSIHGIEGLIFRSLAERMNFTIKLVEQKDKNRG-----EILPDGNF 279
            |:       :|.:.|..|                    :.:.|..:..|:.|     .|:.||.:
Zfish   426 VMYKKNHMHLEGNEKYEG--------------------YCVDLASEIAKHVGIKYRLSIVMDGKY 470

  Fly   280 ----------TGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISP-MG 333
                      .|::..:|.|..::.......:..|.:::..|..:.|..|.:::.......| :.
Zfish   471 GARDPETKSWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 535

  Fly   334 RLTRPFRYIIWSCILVSLIFGFVLICL----------------LKITALP-------GLRNLVLG 375
            ....|..|.||.||:.:.|...|::.|                :|....|       |:
Zfish   536 SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWQLDETDEVKDPQTPPDPPNDFGI------ 594

  Fly   376 RRNRLPFMGMWASLLGGLAL-----YNPQRNFARYILVMWLLQTLILRAAYTGQLYLLLQDVEMR 435
                  |..:|.||  |..:     .:|:....|.:..:|...|||:.::||..|...|....|.
Zfish   595 ------FNSLWFSL--GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMV 651

  Fly   436 SPIKSLSEVLAKDYEFRILPALRTIFKDSMPTTNF--HAVLSLEESLYRLRDEDDPGITVA---- 494
            |||:| :|.|||..|.    |..|:  ||..|..|  .:.:::.|.::......:|.:...
Zfish   652 SPIES-AEDLAKQTEI----AYGTL--DSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFAKTTPD 709

  Fly   495 --------------LLQPTVNQFDFRSGP-----------NKRHLTVLPDPLMTAPLTFYMRPHS 534
                          ||:.|:|::..:..|           :|.:....|             ..|
Zfish   710 GVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATP-------------KGS 761

  Fly   535 YFKRRIDRLIMAMMSSGIVARYR-KMYMDRIKRVSKRRNLEPK--PLSIWRLSGIFVCCAGLYLV 596
            ..:..::..::.:...|::.:.: |.:.|:.:..|...:.:.|  .||:..::|:|....|...:
Zfish   762 ALRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGL 826

  Fly   597 ALIVFILEILTTNHRRLRR 615
            |::|.::|....:....:|
Zfish   827 AMMVALIEFCYKSRAEAKR 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	13/83 (16%)
		Lig_chan	343..592	CDD:459656	60/310 (19%)
gria3b	NP_938174.1	Periplasmic_Binding_Protein_type1	25..398	CDD:471960	6/36 (17%)
		PBP2_iGluR_AMPA	412..794	CDD:270433	79/435 (18%)