Protein Alignment Ir7c and grik3

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_031752773.1
• Gene: grik3 / 100498426
• XenbaseID: XB-GENE-6050069
• Length: 919
• Species: Xenopus tropicalis
• Alignment Length: 615
• Identity: 130/615 - (21%)
• Similarity: 231/615 - (37%)
• Gaps: 125/615 - (20%)

  Fly    70 DRVEMTETDTDPPPPSGLTGRPIAIWFLDSLRSYFRL-----------EMYLNQLG-SPYKRNGF 122
            |:..|......|.|.|||..   .|...|:..:|..:           :|.:|.|. ..:|...|
 Frog   297 DKWSMERHQATPKPESGLLD---GIMTTDAALTYDAVHIVSVCYQRAPQMTVNSLQCHRHKAWRF 358

  Fly   123 FLVIYTGLEDQPMESL--KIMFRR---LLNMYVLNVNVFLQRDGTVHLYTYYPYGPHHCQSSLPV 182
            .......:::...|.|  :|:|.:   |...:.|:: :.|:.||...:.|:
 Frog   359 GSRFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDLDI-ISLKEDGLEKVGTW-------------- 408

  Fly   183 YYTAFQDLAAPANGFGLTK------PLFPRKLTNMHGCEMVVATFEHRPYVIIE--DDPKTPGGR 239
                     .|::|..:|:      |.....|||.   .::|.|....|||:.:  |.|.....|
 Frog   409 ---------NPSDGLNITETARGRGPNISESLTNR---TLIVTTVLEEPYVMFKRSDTPLFGKDR 461

  Fly   240 SIHGIEGL---IFRSLAERMNF--TIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFM 299
                .||.   :.:.:||.:.|  .|:|||  |...|.....|.:.|::|.::|.:.:|......
 Frog   462 ----FEGFCIDLLKKIAEILGFDYDIRLVE--DAKYGSQDEKGQWNGLVKELIDHKADLAVAPLT 520

  Fly   300 YSKARSDLMLPSTSYTSFPI-VLVVPSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKI 363
            .:..|..::..|..:.:..| :|...:.|:...:.....|....||..||::.:   .:.|:|.:
 Frog   521 ITHVREKVIDFSKPFMTLGISILYRKANGTAPSVFSFLNPLSPDIWMYILLAYL---GVSCVLFV 582

  Fly   364 TAL-------------PGLRNLVLGRRNRLPFMGMWASLLGGLALYN----PQRNFARYILVMWL 411
            .|.             || .::|   .|....:..:...:|.|....    |:....|.|..:|.
 Frog   583 IARFSPYEWYDAHPCNPG-TDVV---ENNFTLLNSFWFAVGALMQQGSELMPKALSTRIIGGIWW 643

  Fly   412 LQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAK----DYEFRILPALRTIFKDS-------- 464
            ..|||:.::||..|...|....|.|.|.|..: |||    :|...:..|....||.|
 Frog   644 FFTLIIISSYTANLAAFLTVERMESAIDSADD-LAKQTKIEYGAVVDGATMNFFKKSHISTFEKM 707

  Fly   465 ---MPTTNFHAVLSLEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPNKRHLTVLPDPL---MT 523
               |.:.....|.|.||.:.|:...|    ...|::.|..::..:...|...:..|.|..   :.
 Frog   708 WAFMSSRPSALVKSNEEGIQRVLSAD----YALLMESTAIEYITQRNCNLTQIGGLIDSKGYGIG 768

  Fly   524 APLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNLEPKPLSIWRLSGIFV 588
            .|:      .|.::.||...|:.:..:..:.:.::.:. |.....:.:|.|...|.|..:.|||:
 Frog   769 TPM------GSPYRDRISIAILQLQEADEIHKMKERWW-RSGGCPEEKNKEASALGIQNMGGIFI 826

  Fly   589 CCAGLYLVALIV----FILEILTTNHRRLR 614
            ..||..:::::|    |:.::..|..|..|
 Frog   827 VLAGGLILSVVVAMAEFVYKLRKTAEREQR 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	20/68 (29%)
		Lig_chan	343..592	CDD:459656	61/283 (22%)
grik3	XP_031752773.1	PBP1_iGluR_Kainate	37..417	CDD:380605	27/146 (18%)
		Periplasmic_Binding_Protein_Type_2	433..801	CDD:473866	84/395 (21%)