Protein Alignment Ir7c and grin3b

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 602
• Identity: 109/602 - (18%)
• Similarity: 211/602 - (35%)
• Gaps: 199/602 - (33%)

  Fly   146 LNMYVLNVNVFLQRDGTVHLYTYYPYGPHH------CQSSL--PVYYTA---------------- 186
            |:.::.|.: |..:.|.:::.....:..||      .:.||  |.:.|.
 Frog   340 LSRFLANTS-FSGQTGQIYVSNNLIHTEHHYRIWSLVRDSLGDPTWVTVGGWRQGKMEVEEGLWQ 403

  Fly   187 --FQDLAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPYVI---IEDDPKTPGGR------- 239
              .|.......||..||              :.|.|....|:|.   ::.|...|.|:
 Frog   404 SRIQQWEPAPGGFARTK--------------LRVVTLVEHPFVFTREVDADGSCPAGQMCLDPRT 454

  Fly   240 --------------SIHGIEGLIFRS------------LAERMNFTIKLVEQKDKNRGEILPDGN 278
                          |.:|...|.:::            |:|.:.|..:|.         |:.||.
 Frog   455 NNSAVLDVLFEELNSPNGSVPLEYKTCCYGYCIDLLEKLSEDLRFDFELY---------IVGDGK 510

  Fly   279 F--------TGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYTSFPIVLVVPSGGSISPMGRL 335
            :        ||::..::.|..::....|..:.|||.::..::.:.|..:.::|....:.||:|..
 Frog   511 YGARKGDRWTGLVGDLLSGAAHMAVTSFSINSARSTVIDFTSPFYSTSLGILVRMRDTASPIGAF 575

  Fly   336 TRPFRYIIWSCILVSLIFGFVLICLLKITAL--------------PGLRNLVLGRRNRL----PF 382
            ..|..:.:|..|.|:          |.||||              |..||     |.::    ..
 Frog   576 MWPLHWSMWVGIFVA----------LHITALFLTFYEWKSPFGMTPHGRN-----RTKIFSYSSA 625

  Fly   383 MGMWASLLGG--LALYNPQRNFARYILVMWLLQTLILRAAYTGQLYLL------------LQDVE 433
            :.:..::|.|  ::...|:....|.::.:|.:..|::.::||..|..:            :.|.:
 Frog   626 LNLCYAILFGRTVSSKTPKCCTGRVLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEALSGIHDPK 690

  Fly   434 MRSPIK-----SLSEVLAKDYEFRILPALRTIF-KDSMPTTNFHAVLSLEESLYRLRDEDDPGIT 492
            :..|.:     ::.|..|:.|..:..|.:.... |.|:|.|:        :.::.|: .|.|.:.
 Frog   691 LHHPSQGFRFGTVWESSAEQYIKKSFPEMHNYMRKFSVPATS--------DGVHLLK-TDPPTLN 746

  Fly   493 VALLQPTVNQFDFRSGPNKRHLTV------------LPDPLMTAPLTFYMRPHSYFKRRIDRLIM 545
            ..::...:..::.....:.:.||:            ||   ..:|||          ..|...|.
 Frog   747 AFIMDKALLDYEVSIDSDCKLLTIGKPFAIEGYGIGLP---QNSPLT----------SNISEFIS 798

  Fly   546 AMMSSGIV-ARYRKMYM-----DRIKRVSKRRNLEPKPLSIWRLSGIFV-CCAGLYLVALIVFIL 603
            ...|||.: ..:.|.|.     .|:..|:     |...:.|:..||:|| .|.| :..:|:..::
 Frog   799 RYKSSGFMDTLHDKWYKMVPCGKRVYAVT-----ETLQMGIYHFSGLFVLLCIG-FCGSLLTSLM 857

  Fly   604 E-----ILTTNHRRLRR 615
            |     ::....||.||
 Frog   858 ERVVYHLILPRIRRRRR 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	17/105 (16%)
		Lig_chan	343..592	CDD:459656	57/305 (19%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	10/62 (16%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	79/455 (17%)
		Lig_chan	580..847	CDD:459656	57/308 (19%)