Protein Alignment Ir7c and grik3

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_017206939.1
• Gene: grik3 / 100334689
• ZFINID: ZDB-GENE-211021-1
• Length: 991
• Species: Danio rerio
• Alignment Length: 616
• Identity: 137/616 - (22%)
• Similarity: 234/616 - (37%)
• Gaps: 144/616 - (23%)

  Fly    76 ETDTDPPPPSGLTGRPIAIWFLDSLRSYFRL-----------EMYLNQL----GSPYKRNGFFLV 125
            |....|.|.|||..   .|...|:..:|..:           :|.:|.|    ..|::..|.|:
Zfish   296 ERQIPPKPDSGLLE---GIMTTDAALTYDAVHIVSVSYQHAPQMTVNSLQCHRHKPWRFGGRFM- 356

  Fly   126 IYTGLEDQPMESL--KIMFRRLLNM---YVLNVNVFLQRDGTVHLYTYYPYGPHHCQSSLPVYYT 185
              :.:::...:.|  ::.|.|...:   :.|:: |.|:.||...:      |.......|.:...
Zfish   357 --SFIKESHWDGLTGRLCFNRTTGLRTDFDLDI-VSLKEDGLQKV------GKWSASGGLNITEV 412

  Fly   186 AFQDLAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIEGL--- 247
            ..|      ||..:|..|..|.|        |:.|....|||:::...|...|..  ..||.
Zfish   413 PRQ------NGMNITDSLSNRSL--------VITTILEEPYVMLKKSDKALVGND--RFEGFCID 461

  Fly   248 IFRSLAERMNFTIKLVEQKDKNRGEILPDGNF---------TGILKMMVDGEVNLTF----VCFM 299
            :.:.||..:.|:.::         .::|||.:         .|:::.:::...:|..    :.||
Zfish   462 LLKELASILGFSYEI---------HLVPDGKYGFQDDKGQWNGMIRELMEHRADLAVAPLTITFM 517

  Fly   300 YSKARSDLMLPSTSYTSFPIVLVVPSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKIT 364
            ..|| .|...|..: |...|:...|:..: |.......|....||..||::.:   .:.|:|.:.
Zfish   518 REKA-IDFSKPFLN-TGISILYRKPNSTN-SGFFSFLNPMTPDIWVYILLAYL---GVSCVLFVI 576

  Fly   365 AL-------------PGL----RNLVLGRRNRLPFMGMWASLLGGLALYNPQRNFARYILVMWLL 412
            |.             ||.    .|..|  .|...| |:.:.:..|..|. |:....|.|..:|..
Zfish   577 ARFSPYEWYDAHPCNPGSDVVENNFTL--LNSFWF-GVGSLMQQGSELM-PKALSTRIIGGIWWF 637

  Fly   413 QTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKD--YEFRILP--ALRTIFK----------- 462
            .|||:.::||..|...|....|.||:.|..: |||.  .|:.::.  |..:.||
Zfish   638 FTLIIISSYTANLAAFLTVERMDSPVDSADD-LAKQTKIEYGVVKDGATMSFFKKSRVSTFEKMW 701

  Fly   463 ---DSMPTTNFHAVLSLEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPNKRHLTVLPDPLMTA 524
               .|..:|:|  |.|:|:.:.|:...|    ...|::.|..::..|...|   ||.:...:.:.
Zfish   702 AFMSSRQSTSF--VKSIEDGIQRVLKSD----YALLMESTTIEYVTRRNCN---LTQVGGIIDSK 757

  Fly   525 PLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNLEPK-----PLSIWRLS 584
            .........|.::.:|...|:.::..|      :::|.:.|..|....||.:     |:.|..|.
Zfish   758 GYGIGTPKGSPYRDKITIAILGILEDG------RLHMLKEKWWSGSSCLEDERYETGPMGIQNLG 816

  Fly   585 GIFVCCA-GLYL---VALIVFILEILTTNHR 611
            |||:..| ||.|   ||:..||.::..|..|
Zfish   817 GIFIVLASGLVLSVFVAIGEFIYKLRKTAER 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/73 (19%)
		Lig_chan	343..592	CDD:459656	68/289 (24%)
grik3	XP_017206939.1	PBP1_iGluR_Kainate	32..410	CDD:380605	25/126 (20%)
		Periplasmic_Binding_Protein_Type_2	426..794	CDD:473866	88/412 (21%)