Protein Alignment Ir7c and grin3bb

DIOPT Version :10

• Sequence 1: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_017213803.2
• Gene: grin3bb / 100333101
• ZFINID: ZDB-GENE-131122-77
• Length: 1114
• Species: Danio rerio
• Alignment Length: 730
• Identity: 134/730 - (18%)
• Similarity: 243/730 - (33%)
• Gaps: 251/730 - (34%)

  Fly    52 AALGRSSGTGRI----QFLLEDDRVEMTETDTDPPPPS---------------------GLTGRP 91
            |||..|..|.|:    .||.|...::.:      ||.|                     ||| .|
Zfish   220 AALNLSHSTARMANISDFLSEHFNLDHS------PPASVLLFGADPECASSVLRSAHDLGLT-LP 277

  Fly    92 IAIWFL------DSLRSYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQPM-----ESLKIMFRRL 145
            ...|.:      |:|.|          :|.|     ..|:.|..::.:|:     ::|:::.|.:
Zfish   278 TVHWIMGHPLSPDALHS----------IGLP-----LGLLAYGEVDHKPLDFYISDALQLINRAV 327

  Fly   146 LNMYVLNVNV---------------------------FLQRDGTVHLYTYYPYGPHHCQSSLPVY 183
            ....|:..::                           ||.....|.|     .||...|.:|...
Zfish   328 TAATVVRPDLALIQNMVNCFDKPNKHELPSSGQYIARFLSNTSFVGL-----TGPVIVQRNLSRV 387

  Fly   184 YTAFQ----DLAAPANG-------------------FGLTKPLFPRKLTN--------------- 210
            :|:.:    .|...|.|                   .||.:...||:.|.
Zfish   388 HTSHKVHIWSLRRDAVGQPTWVTVGSWEGGRLNVEEQGLWQGSSPRQRTEGQMGREGRRWRAGFP 452

  Fly   211 MHGCEMVVATFEHRPYVI---IEDDPKTPGGR--------SIHGIEGL----------------- 247
            :.|..:.|.|....|:|.   :::|...|.|:        |...::.|
Zfish   453 VSGSRLRVVTLVEHPFVFTREVDEDGNCPAGQYCLDAGTNSSETLDHLYAERAQGNKSFLPPDYS 517

  Fly   248 ---------IFRSLAERMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTFVCFMYSKA 303
                     :...|:|.|||...|....|...|.: ..|.:||::..::.|..::....|..:.|
Zfish   518 KCCYGYCIDLLEKLSEDMNFEFDLYIVGDGKYGAV-KGGQWTGLVGDLLSGVADMAVTSFSINSA 581

  Fly   304 RSDLMLPSTSYTSFPIVLVVPSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICLLKITALPG 368
            ||.::..::.:.|..:.::|.|..:.:|:|....|..:.:|..|.|:|....:.:.|.:..:..|
Zfish   582 RSKVIDFTSPFFSTSLGILVRSKDTAAPIGAFMWPLHWSMWMGIFVALHITALFLTLYEWKSPFG 646

  Fly   369 LRNLVLGRRNRLPFMG-------MWASLLG-GLALYNPQRNFARYILVMWLLQTLILRAAYTGQL 425
               :....|||:....       .:|.|.| .::...|:....|:::.:|.:..|::.::||..|
Zfish   647 ---MTPHGRNRVKVFSYSSALNLCYAILFGRTVSSKTPKCWTGRFLMNLWAIFCLLVLSSYTANL 708

  Fly   426 YLL------------LQDVEMRSPIK-----SLSEVLAKDYEFRILPALRTIFKDSMPTTNFHAV 473
            ..:            :.|.::..|.:     ::.|..|:||..:..|.:....:.....|....|
Zfish   709 AAVMVGEKTFEEVSGIHDAKLHHPSQGFRFGTVRESSAEDYMKKSFPEMHEYMRKFNEPTTPDGV 773

  Fly   474 LSLEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPNKRHLTV------------LPDPLMTAPL 526
            .:|:        .|.|.:...::...:..::.....:.:.|||            ||   ..:||
Zfish   774 ATLK--------TDPPQLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLP---QNSPL 827

  Fly   527 TFYMRPHSYFKRRIDRLIMAMMSSGIVARYRK-MYMDRI-----------KRVSKRRNLEPKPLS 579
            |..:                   |..|:||:. .|||.:           |||.  ...|...:.
Zfish   828 TSNI-------------------SEFVSRYKSDGYMDMLHDKWYKVVPCGKRVF--AVTETLQMG 871

  Fly   580 IWRLSGIFV-CCAGL 593
            |...||:|| .|.|:
Zfish   872 IRHFSGLFVLLCVGV 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	18/98 (18%)
		Lig_chan	343..592	CDD:459656	56/298 (19%)
grin3bb	XP_017213803.2	Periplasmic_Binding_Protein_type1	39..427	CDD:471960	41/233 (18%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	77/428 (18%)
		Lig_chan	618..885	CDD:459656	56/301 (19%)