DRSC/TRiP Functional Genomics Resources

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Protein Alignment Acsf3 and hll

DIOPT Version :10

Sequence 1:NP_996360.2 Gene:Acsf3 / 31668 FlyBaseID:FBgn0029945 Length:610 Species:Drosophila melanogaster
Sequence 2:NP_609696.1 Gene:hll / 34822 FlyBaseID:FBgn0286723 Length:681 Species:Drosophila melanogaster


Alignment Length:592 Identity:112/592 - (18%)
Similarity:191/592 - (32%) Gaps:214/592 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 SNVTYLCSNNALWIAIQWSCWISGQVAV---PLESGQAIDQLQRQASNCKTKLLIATKEFESLAQ 156
            |:|..|..|...|...::....:|.|..   |..|.:|:..:                       
  Fly    95 SSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHV----------------------- 136

  Fly   157 ELSQGVKSATIILDHSFLPTAESVSSTSMYAKQLVAIQGVI---------------VTENTFPND 206
             |:.|..|..::.|...:....::.......|.::.:.|..               :.|.||.::
  Fly   137 -LATGESSVCVVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQEQTFSSE 200

  Fly   207 -----------FYSKAPAMLIYTPNAVNSPKPVLLTHRNI-------EAQMRCL-IGTWHLGPTD 252
                       ..:...||||:|...|..||.|:|:|.|:       .|.|:.: :|      .:
  Fly   201 LKEELLARESRIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDIQVG------KE 259

  Fly   253 CMLPILSMNRMHAALAAV---LSVGGNVVLQQKFDGHNAWSALLG--INSPSKQRVTLFLAMPIV 312
            ..:..|.::.:.|.:..|   ||..|.|....|       .||.|  |.:..|.|.|....:|.|
  Fly   260 SFVSYLPLSHVAAQIFDVFLGLSHAGCVTFADK-------DALKGTLIKTFRKARPTKMFGVPRV 317

  Fly   313 YKRLIVEYEKMFAKDSRMVEY-----------IVNHCRQKIRLMATAFALLPDSVFYRW------ 360
            :::|   .|::.|.:::...|           :..|   :..|||.....:..:..| |      
  Fly   318 FEKL---QERLVAAEAKARPYSRLLLARARAAVAEH---QTTLMAGKSPSIYGNAKY-WLACRVV 375

  Fly   361 ---REITGQN--------------------------IYEYYGMMETGLVLGHPLNKRQRDSPHNG 396
               ||:.|.:                          :.|.|||.||                   
  Fly   376 KPIREMIGVDNCRVFFTGGAPTSEELKQFFLGLDIALGECYGMSET------------------- 421

  Fly   397 PTAVAMANNTAPNDYRPGTLGSPLKGVTARLISNKGDELITCKNELGGSVDSGLIPVEDIGGDAS 461
             :.....|....|.|   :.|...:|||.:                        |...|..|.  
  Fly   422 -SGAITLNVDISNLY---SAGQACEGVTLK------------------------IHEPDCNGQ-- 456

  Fly   462 LAGTIIGELQIAGSNLVSNTLANNNQEMEHKGTTNNEEQENNQDGFFKTGDICAY--RNGNFYFL 524
                  ||:.:.| .||.         |.:.|..:..|:...:||:..:||: .|  ..||....
  Fly   457 ------GEILMRG-RLVF---------MGYLGLPDKTEETVKEDGWLHSGDL-GYIDPKGNLIIS 504

  Fly   525 SKSSD-IFTVGGYKVYGSEIKKVLISH-PNINDVAVLGIPNKMWGHR--LGVICIVSPDAD---- 581
            .:..: |.|.||..:....|::::... |.:::|.::|      .||  |.|:..:....|    
  Fly   505 GRLKELIITAGGENIPPVHIEELIKKELPCVSNVLLIG------DHRKYLTVLLSLKTKCDAKTG 563

  Fly   582 IDLDAIK 588
            |.|||::
  Fly   564 IPLDALR 570

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Acsf3NP_996360.2 Adenylate forming domain, Class I superfamily 58..603 CDD:473059 112/592 (19%)
hllNP_609696.1 Adenylate forming domain, Class I superfamily 62..680 CDD:473059 112/592 (19%)

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