Protein Alignment Acsf3 and Acsf3

DIOPT Version :10

• Sequence 1: NP_996360.2
• Gene: Acsf3 / 31668
• FlyBaseID: FBgn0029945
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_659181.2
• Gene: Acsf3 / 257633
• MGIID: 2182591
• Length: 583
• Species: Mus musculus
• Alignment Length: 610
• Identity: 171/610 - (28%)
• Similarity: 275/610 - (45%)
• Gaps: 104/610 - (17%)

  Fly    18 LCSAELI---HKDGFIEKLRHSF---DEEERSNVVVPTFKKAMLYPDEIAVKDINGEYTYFQLYM 76
            |.|::||   |:.       ||.   ..|..::..||.|.:|:.:.|.||:.|..|.:||.:||.
Mouse    16 LASSQLIPRRHRG-------HSLLPTTPEAHTDGSVPVFIRALAFGDRIALIDKYGHHTYRELYD 73

  Fly    77 AAKRLGIQISNI--C--GGAALSNVTYLCSNNALWIAIQWSCWISGQVAVPLESGQAIDQLQRQA 137
            .:..|..:|..:  |  |......|::||||:..::..||:.|:||.|||||.......||:...
Mouse    74 RSLCLAQEICRLQGCKVGDLQEERVSFLCSNDVSYVVAQWASWMSGGVAVPLYWKHPEAQLEYFI 138

  Fly   138 SNCKTKLLIATKEF----ESLAQELSQGVKSATIILDHSFLPTAESV--SSTSMYAKQLVAIQGV 196
            .:.::.|::..:|:    ..|||.|  ||         ..||...:|  .:|....:|.|...|
Mouse   139 QDSRSSLVVVGQEYLERLSPLAQRL--GV---------PLLPLTPAVYHGATEKPTEQPVEESG- 191

  Fly   197 IVTENTFPNDFYSKAPAMLIYTPNAVNSPKPVLLTHRNIEAQMRCLIGTWHLGPTDCMLPILSMN 261
                       :....||:.||......||..|.||||:.|.:..|:.:|.....|.:|.:|.::
Mouse   192 -----------WRDRGAMIFYTSGTTGRPKGALSTHRNLAAVVTGLVHSWAWTKNDVILHVLPLH 245

  Fly   262 RMHAA---LAAVLSVGGNVVLQQKFDGHNAWSALLGINSPSKQRVTLFLAMPIVYKRLIVEYEKM 323
            .:|..   |...|.||...|:..:|.....|...|...:|   ::|:|:|:|.||.:|:..|:|.
Mouse   246 HVHGVVNKLLCPLWVGATCVMLPEFSAQQVWEKFLSSEAP---QITVFMAVPTVYSKLLDYYDKH 307

  Fly   324 FAKDSRMVEYIVNHCRQKIRLMATAFALLPDSVFYRWREITGQNIYEYYGMMETGLVLGHPLNKR 388
            |.: ..:.:::...|:::||||.:..|.||..:..:||..||..:.|.|||.|.|:.|.:||.:.
Mouse   308 FTQ-PHVQDFVRAVCKERIRLMVSGSAALPVPLLEKWRSATGHTLLERYGMTEIGMALSNPLTEA 371

  Fly   389 QRDSPHNGPTAVAMANNTAPNDYRPGTLGSPLKGVTARLIS---NKGDELITCK--NELGGSVDS 448
            :                      .||::|:||.||..|:||   .||...|...  ||.|..|..
Mouse   372 R----------------------VPGSVGTPLPGVEVRIISENPQKGSPYIIHAEGNERGTKVTP 414

  Fly   449 GLIPVEDIGGDASLAGTIIGELQIAGSNLVSNTLANNNQEMEHKGTTNNEEQENNQDGFFKTGDI 513
            |....|             |||.:.|.::.          .|:.......:.....||:|:|||.
Mouse   415 GFEEKE-------------GELLVRGPSVF----------REYWDKPEETKSAFTSDGWFRTGDT 456

  Fly   514 CAYRNGNFYFLSKSS-DIFTVGGYKVYGSEIKKVLISHPNINDVAVLGIPNKMWGHRLGVICIVS 577
            ..:::..::...::| ||...|||||...||::.|::||:|.||||:|:|:..||.|:..:..:.
Mouse   457 AVFKDARYWIRGRTSVDIIKTGGYKVSALEIERHLLAHPSITDVAVIGVPDMTWGQRVTAVVALQ 521

  Fly   578 PDADIDLDAIKTYCYRHLPAHKCPT 602
            ....:....:|.:....|..:..|:
Mouse   522 EGHSLSHGDLKEWARGVLAPYAVPS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsf3	NP_996360.2	Adenylate forming domain, Class I superfamily	58..603	CDD:473059	159/564 (28%)
Acsf3	NP_659181.2	MCS	55..569	CDD:341264	156/532 (29%)