Protein Alignment Acsf3 and mec-18

DIOPT Version :10

• Sequence 1: NP_996360.2
• Gene: Acsf3 / 31668
• FlyBaseID: FBgn0029945
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_508731.3
• Gene: mec-18 / 180701
• WormBaseID: WBGene00003179
• Length: 638
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 113/608 - (18%)
• Similarity: 205/608 - (33%)
• Gaps: 196/608 - (32%)

  Fly    50 FKKAMLYPDEIAVKDING--EYTYFQL----YMAAKRL-GIQISNICGGAALSNVTYLCSNNALW 107
            |.|...:...:|:.|::.  ::.|.::    .|.|.|| .:|:::   |   |.|..:.......
 Worm    24 FSKISAHGSNLAIVDVDSGKQWRYSEIRNWCEMCATRLKELQVTS---G---SRVAVITGTTGQA 82

  Fly   108 IAIQWSCWISGQVAVPLESGQAIDQL--------------------------------------- 133
            |.:..:|.|.|..||.:....|:|::
 Worm    83 IFVHLACSIIGCSAVAVNGWNAVDEIWTLVDLSEATHLIVENQFMQKADDVRRKAQMRGGGRIKH 147

  Fly   134 QRQASNCKT----------KLLIATKEFESLAQELSQGVKSATIILDHSFLPTAESVSSTSMYAK 188
            .||..:..|          |..|..|:...|.:|:|....:.|.:|..........||..|..:|
 Worm   148 VRQIEDVLTAERINVDSARKRSIDVKQKPPLVKEMSLAKINLTPVLPEDIADLTSPVSEVSGQSK 212

  Fly   189 QLVA-IQGVIVTE---NTFPNDFYSKAPAMLIYTPNAVNSPKPVLLTHRNIEAQMRCLIGTWHLG 249
            :|.. ::..:|..   .|.......:.|.::::|.......|...|:||::...:: .|.....|
 Worm   213 ELNGDVESSVVDSEEVQTPIQQVSGQNPLLILFTSGTTGLAKAAELSHRSLIINIQ-QISLPLYG 276

  Fly   250 PTDC----MLPILSMNRMHAALAAVLSV--GGNVVLQQKFDGHNAWSALLGINSPSKQRVTLFLA 308
            |...    :|| ||:..::..::|..::  |.::.|                  .|||...||:
 Worm   277 PVQTKERFLLP-LSIAHIYGIVSAYYALINGASLYL------------------ISKQSNRLFM- 321

  Fly   309 MPIVYKRLIVEYEKMFAKDSRMVEYIVNHCRQKIRLMATAFALLPDSVFYRWREITGQNIYEYYG 373
                                   |.:||:   :|.:|....|::      .|  :....|.:.|.
 Worm   322 -----------------------ETLVNN---QINVMHITPAIV------HW--MATDAIVDDYK 352

  Fly   374 M--METGLVLGHPLNKRQRDSPHNGPTAVAMANNTAPNDYRPG---------------------T 415
            .  :.:.|..|.|::..         :|.||.:.....|:|..                     :
 Worm   353 TPNLRSVLCAGAPIDSN---------SAAAMKSRLNIKDFRQSFGMTELGGICTMSPYLDEKIES 408

  Fly   416 LGSPLKGVTARLISNKGDELITCKNELGGSVDSGLIPVEDIGGDASLAGTIIGELQIAGSNLVSN 480
            :|:||.|:..::::.:..:|  |            :|.:.            |::.:.|..:...
 Worm   409 VGNPLPGMLFKVVNWETKQL--C------------LPRQP------------GQIIVLGPQVSPC 447

  Fly   481 TLANNNQEMEHKGTTNNEEQENNQDGFFKTGDICAYRN-GNFYFLSKSSDIFTVGGYKVYGSEIK 544
            ...|.....|....|          ||.||||...|.. |..|.|.:..||....|..:..||::
 Worm   448 YYKNPKATSELFDAT----------GFVKTGDAGFYDEVGRIYVLDRIKDIIKCKGTMICPSEVE 502

  Fly   545 KVLISHPNINDVAVLGIPNKMWG 567
            .||.:|..|:|.||:|..:.:.|
 Worm   503 LVLRAHAGIDDCAVVGRQDHVTG 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsf3	NP_996360.2	Adenylate forming domain, Class I superfamily	58..603	CDD:473059	111/600 (19%)
mec-18	NP_508731.3	Firefly_Luc_like	35..579	CDD:341237	111/597 (19%)