Protein Alignment unc-119 and unc119a2

DIOPT Version :10

• Sequence 1: NP_572389.1
• Gene: unc-119 / 31664
• FlyBaseID: FBgn0025549
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001035484.1
• Gene: unc119a2 / 678653
• ZFINID: ZDB-GENE-050201-2
• Length: 264
• Species: Danio rerio
• Alignment Length: 278
• Identity: 143/278 - (51%)
• Similarity: 176/278 - (63%)
• Gaps: 43/278 - (15%)

  Fly     5 GKQLNPVQSSGAGAVTTSSSAAAGSSSSNSGVEANGGSGGS-SGAAAAGAGASGDAKRPAE---- 64
            |...:|..|..:|.|.      .||.||::|...||.:..| .|:.|.....|.:|.:..:
Zfish     9 GNSQDPSSSKKSGGVN------PGSCSSSNGDTGNGNNRHSIRGSKANSKPDSTEAMKVKKGCNT 67

  Fly    65 ---------------SSSVTPDEVLHLTKITDDYLCSANANVFEIDFTRFKIRDLESGAVLFEIA 114
                           :.:::|::||.|.|||::||||...|::.||||||||||:|:|.|||||.
Zfish    68 TDLGVPVTTEEELLANKTISPEDVLGLQKITENYLCSPEDNLYNIDFTRFKIRDMETGTVLFEIT 132

  Fly   115 KPPSEQYPEGLSSDETMLAAAEKLSLDDTADPNAGRYVRYQFTPAFLNLKTVGATVEFTVGSQPL 179
            ||||..  .|...|               .||||||:||||||||||.|:.||||||||||..|:
Zfish   133 KPPSTD--RGDKRD---------------VDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDIPI 180

  Fly   180 NNFRMIERHFFRDRLLKTFDFEFGFCFPFSKNTVEHIYEFPNLPPDLVAEMISSPFETRSDSFYF 244
            |||||||||:||::|||:||||||||.|.||||.|||||||.|..||:.|||..|:||:||||||
Zfish   181 NNFRMIERHYFREQLLKSFDFEFGFCIPSSKNTCEHIYEFPPLSEDLIREMILHPYETQSDSFYF 245

  Fly   245 VGNRLVMHNKADYAYDGG 262
            |.|:|||||||||:|.||
Zfish   246 VDNKLVMHNKADYSYSGG 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-119	NP_572389.1	GMP_PDE_delta	89..259	CDD:428436	112/169 (66%)
unc119a2	NP_001035484.1	GMP_PDE_delta	107..260	CDD:428436	112/169 (66%)