Protein Alignment Cph and bcl11ba

DIOPT Version :10

• Sequence 1: NP_001356899.1
• Gene: Cph / 31660
• FlyBaseID: FBgn0029939
• Length: 1254
• Species: Drosophila melanogaster
• Sequence 2: NP_001315335.1
• Gene: bcl11ba / 100093707
• ZFINID: ZDB-GENE-061207-62
• Length: 814
• Species: Danio rerio
• Alignment Length: 1167
• Identity: 302/1167 - (25%)
• Similarity: 410/1167 - (35%)
• Gaps: 520/1167 - (44%)

  Fly    32 DILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQ-CATQNPQMDRDAEEGRPLSLVNRRPSISA 95
            |:||||.||..|.|.||:.||:||..||.....|. |      .|:.|:...|
Zfish    58 DLLTCGQCQLTFPLGDILLFIEHKKKQCQALTSGHGC------YDKMADRNSP------------ 104

  Fly    96 PISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDEND 160
                  |.|.:....|.                          .|.::   |...||:. .||..
Zfish   105 ------SPPRAELRKVV--------------------------EPVEI---GIQVTPEE-EDERL 133

  Fly   161 NTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEG 225
            .|.||                            ..|              |||
Zfish   134 LTPPK----------------------------GIC--------------PKQ------------ 144

  Fly   226 VNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHS 290
                            |..||.|              .|||:|.|:|||..:|:||.|:||.|::
Zfish   145 ----------------ESGLAGR--------------DEPSSYICTTCKQPFTNAWFLLQHAQNT 179

  Fly   291 HGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSP 355
            ||::||:|:.....:||                            |:..:.|            |
Zfish   180 HGIRIYLETNSSNTSLT----------------------------PRITIPP------------P 204

  Fly   356 LGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENL 420
            :||          .|...:.|.|..|.:
Zfish   205 IGA----------ESIPQSPLTNFLGDN------------------------------------- 222

  Fly   421 ASAMAAGMRHHPLLPPPEAMHANPFQLLRM--PL----PPALAQAGNVVPTVAPLFGRPSPADH- 478
                                  |||.||||  ||    ||...:  |.:|...| |..|.|..|
Zfish   223 ----------------------NPFHLLRMTGPLLREPPPGFVE--NRIPNTPP-FVSPPPRHHL 262

  Fly   479 --YRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPP 541
              :|:|:|.:|:.                          |::|
Zfish   263 DPHRLERLSAEEM--------------------------GLIS---------------------- 279

  Fly   542 AALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKL 606
                                                   |.....::..::||         :.:
Zfish   280 ---------------------------------------QHPSAFERVMRMTP---------MAM 296

  Fly   607 EPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSP--SPRQKQSPH-FASPSPSQQQQQQLATIPRPH 668
            |.|.||| |:|||:|||.         |:|:|  ||.:....| ..:|:|.|         |.|.
Zfish   297 ESQSMDF-SRRLRELAGN---------NNSTPPLSPSRANPMHRLLNPNPFQ---------PSPK 342

  Fly   669 S---LTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFEN 730
            |   .|||                |...|.:::|||...|...         ||.:|.|.|:|::
Zfish   343 SPFLSTPP----------------LPPMPPNSTTPPQTQGKSK---------SCEFCGKTFKFQS 382

  Fly   731 NLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEAD 795
            ||::|:|:|||||||||..||..||...||.:||:.|...:.....:  .|||.:..|
Zfish   383 NLVVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKSGSMTGR--SDDGLSTTS------- 438

  Fly   796 NDEDPNPDESEEELGDGDNDPDGDGDLDG------EDEDEDELEECEDMDYKAEDLSVS-----N 849
               .|.|..| :..|:|..:.|||...:|      |:|:|:|.||.|:......:.|:.     |
Zfish   439 ---SPEPGTS-DVTGEGIKNRDGDFKGEGMLQDNEEEEEEEEEEELENESRPESNFSMDSEFCRN 499

  Fly   850 RIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQY-------------SEAYKQALQESGRKEAA 901
            |.:|.    |..|...|..:|::::..|||:|.||             |:...:..:|.|..::.
Zfish   500 RENGS----KPPSDEKTLSLGKMVENVGLSSIQQYNNLIVDNRKRLPFSKRISEVQREVGDDDSV 560

  Fly   902 AAAAAAAAAADNNNRG-GAGAPLSDKLNGL------PVAALRLRDEFAKNC-------------- 945
            .........|..|.|. |:|    |..:||      |:.:..|.:...|..
Zfish   561 VGEMDQVERATVNGRNCGSG----DSFSGLFPRKPTPITSPSLSNSSNKRIKIEKDLDIPPAPLI 621

  Fly   946 ---NMFQQPQDGGAPSQVPLFNPF-------PNPFELSKRMKMDGGDWWGMSQALHRNEALFENL 1000
               |::.|...|.|.|:..:.:||       .:||..|.....:.|                 :|
Zfish   622 PSENVYSQWLVGYAASRHFIKDPFLGFTDSRQSPFATSSEHSSENG-----------------SL 669

  Fly  1001 K-------LKPLGLGGANSLIQG---PLL----------KKESRQRNDTCEFCGKVFKNCSNLTV 1045
            :       |...||.|.:....|   |.|          .|||| |:||||:|||||||||||||
Zfish   670 RFSTPPGDLLDGGLSGRSGTASGGSTPHLGGGPGPGRPSSKESR-RSDTCEYCGKVFKNCSNLTV 733

  Fly  1046 HRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRK 1107
            ||||||||:|||||||:|||||||||||||||||:.||:||||..|.|||||.|||||||:|
Zfish   734 HRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQLGKEVYRCDICQMPFSVYSTLEKHMKK 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cph	NP_001356899.1	zf-C2H2	717..739	CDD:395048	10/21 (48%)
		C2H2 Zn finger	719..739	CDD:275368	9/19 (47%)
		zf-H2C2_2	731..756	CDD:463886	16/24 (67%)
		C2H2 Zn finger	747..767	CDD:275368	9/19 (47%)
		zf-C2H2	1029..1050	CDD:395048	19/20 (95%)
		C2H2 Zn finger	1030..1050	CDD:275368	18/19 (95%)
		zf-H2C2_2	1042..1067	CDD:463886	22/24 (92%)
		C2H2 Zn finger	1058..1078	CDD:275368	18/19 (95%)
		C2H2 Zn finger	1088..1106	CDD:275368	13/17 (76%)
bcl11ba	NP_001315335.1	zf-C2H2	370..391	CDD:395048	10/20 (50%)
		C2H2 Zn finger	371..391	CDD:275368	9/19 (47%)
		zf-H2C2_2	383..408	CDD:463886	16/24 (67%)
		C2H2 Zn finger	399..419	CDD:275368	9/19 (47%)
		zf-C2H2	717..738	CDD:395048	19/20 (95%)
		C2H2 Zn finger	718..738	CDD:275368	18/19 (95%)
		zf-H2C2_2	730..755	CDD:463886	22/24 (92%)
		C2H2 Zn finger	746..766	CDD:275368	18/19 (95%)
		C2H2 Zn finger	776..794	CDD:275368	13/17 (76%)