Protein Alignment Inx6 and inx-21

DIOPT Version :10

• Sequence 1: NP_572374.1
• Gene: Inx6 / 31645
• FlyBaseID: FBgn0027107
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_491187.2
• Gene: inx-21 / 171930
• WormBaseID: WBGene00002143
• Length: 481
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 106/558 - (18%)
• Similarity: 183/558 - (32%)
• Gaps: 232/558 - (41%)

  Fly    26 LHSKCTIVILLTCTFLLSAKQYFGEPILCLSSE----RQADYVQSYCWTMGTYILPAEVD----- 81
            ||: .||.||:....||::|..||.||:|...:    ...||....|:    |....:||
 Worm    27 LHN-TTIAILVFLFILLASKPMFGSPIVCQVPKDWPSSSVDYFTDICY----YGQREKVDIQHRI 86

  Fly    82 -RDGGSSWEYALYAPTSTAAETFNVSSLRALVAQNEQYARFISIAEGVGPETRGVTKRMYLRYYQ 145
             |.||                       |..|..|               .|.|.::     :|.
 Worm    87 SRAGG-----------------------RGTVTVN---------------LTTGTSE-----FYM 108

  Fly   146 WVFMILLFQSLLFYFPSFLWKV------------------------------WEGQRMEQLCCEV 180
            ||.::.:....|...|:|.||.                              .||.|..:|..::
 Worm   109 WVPLVPILLVALCLLPAFFWKFVGLDCFNGMDIVSFLEFYEQTDDPGERLVEMEGWRRRKLAAQL 173

  Fly   181 GDALIVEATYRTRLQ------MLTRYFR-----AQF---------APIHWCYS------------ 213
            ...::.:..:...|.      :|.::||     |||         ....|.|:
 Worm   174 NKWIMAKRNFFCGLSQTMIIYVLMKWFRTILFIAQFWIIADVFGDGNFFWGYADLARIANGDSIN 238

  Fly   214 -IKYAF-----CELLNVFISILNFWLMDVVFNGFWYKYIHALAAIPVYDWNLWNLMTSRVFPKVA 272
             :|.:|     |.:..:.:||           ||:..|.:|.:|                   ||
 Worm   239 PLKGSFTLISGCRVQRLAMSI-----------GFYRSYTNAHSA-------------------VA 273

  Fly   273 KCEMFVYGPSGTPNIMDILCVLPLNILNEKIFAVLYVWFLFIALLAIMNILYRLLVICCPELR-- 335
            :                  |:|..|.||.|.|.|||.|||.::.:::.:.::..:::..|:.|
 Worm   274 R------------------CMLSANFLNAKAFLVLYWWFLLVSFISLCSAIHYTIILLVPQYRRH 320

  Fly   336 --LQLLRT---------------HL-NGMPKSHVREVLASAGYGDWFVLMCVSINVNPTLFRELL 382
              ..::||               || ...|..::.|.|.:.|:                   .::
 Worm   321 EFKSMIRTEDHFIERYGEPHPNLHLGKEAPLEYLVEHLGNDGF-------------------LVV 366

  Fly   383 EQLYAKLNQARC---TEPVF-------AEQPCQQVPQLAQVPQLFSHAKLDRCPSRNCSLLID-- 435
            |.:|..|:...|   ||.::       .|:..:......:..::....::|....|| |..||
 Worm   367 EMVYDMLHHYECDRFTEHIWMHIIVHNGEEDFEDDEIENKKIKIVDEMEMDGAGDRN-SGGIDKK 430

  Fly   436 PTADRHSIC-----TESSHRVTAMPTAPTLNLMAPNDE 468
            .|.|..|..     .:|:.:|:...:.|:: :|:.:||
 Worm   431 ETNDWSSSAGTSKNKDSTSKVSLSASQPSM-MMSESDE 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Inx6	NP_572374.1	Innexin	21..388	CDD:459975	86/459 (19%)
inx-21	NP_491187.2	Innexin	21..388	CDD:459975	90/475 (19%)