DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14439 and HXT17

DIOPT Version :9

Sequence 1:	NP_001188550.1	Gene:	CG14439 / 31614	FlyBaseID:	FBgn0029898	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_014470.1	Gene:	HXT17 / 855809	SGDID:	S000005355	Length:	564	Species:	Saccharomyces cerevisiae

Alignment Length:	484	Identity:	95/484 - (19%)
Similarity:	174/484 - (35%)	Gaps:	128/484 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 CYALDFNG----------TGYCEW--------NYNGLGIDYQI------LAGPTFILIFTIAGVF 117
            ||.:.|.|          .|:...        :|.....:|.:      |....|.:...|.|:.
Yeast    61 CYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLI 125

  Fly   118 MGFAADKYNRVNMLTVCTVIFGIAMILQGTVKEYW-QLVILRMIMAAGESGCNPLATGIMSDIFP 181
            ....||...|...:.:..:::.:..|:|.:....| |..:.::|...|..||:.|...::|:|.|
Yeast   126 FARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAP 190

  Fly   182 EDKRALVMAIF----NWGIYGGYGIAFPVGRYITKLNFWNLGWRVCYLGAGVLTVIM-------- 234
            .|.|..:::::    .:||:.||...:...:|..... |.:...:|:|...::.:.|
Yeast   191 TDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQ-WRVPLGLCFLWTLIIIIGMLLVPESPR 254

  Fly   235 ------------AALTGTTLREPE-----------------RKAIGEGD-RQTSSGKPVSLWQVI 269
                        |::.......||                 ::.:||.. ::..|.|...|.::|
Yeast   255 YLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLI 319

  Fly   270 KNPAMIMLMIAASIRHCGGMTFAYNADLYYNTYFPDVDL--GWWLFGVTIGIGSVGVVVGGIVSD 332
            ..     :::...::..|...|.:    |..|.|..|.|  |   |..:|.:|:|. ....|::.
Yeast   320 TG-----ILVQTFLQLTGENYFFF----YGTTIFKSVGLTDG---FETSIVLGTVN-FFSTIIAV 371

  Fly   333 KIVAKMGIRSRAFVLAVSQLIATLPAFGSVYFDPLW--------------AMITLGLSYF--FAE 381
            .:|.|:| |.:..:...:.::|.:..|.|:....|:              |||.....|.  ||.
Yeast   372 MVVDKIG-RRKCLLFGAAGMMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFAT 435

  Fly   382 MWFGIVFAIVVEIVPLRVRSSTIGV---------FLFVMNNIGGNLPILVDPVAKILGYRGSIMI 437
            .|..:.:.:|.|..|.:|:|..:.:         ||     ||...|.:.          |||..
Yeast   436 TWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFL-----IGFFTPFIT----------GSIHF 485

  Fly   438 FYA-GFYGISSILFFITCFLLEGKPDEVG 465
            :|. .|.|....:|....|.|   |:.:|
Yeast   486 YYGYVFVGCLVAMFLYVFFFL---PETIG 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14439	NP_001188550.1	MFS_1	94..416	CDD:284993	76/397 (19%)
CG14439	NP_001188550.1	MFS	107..452	CDD:119392	83/415 (20%)
HXT17	NP_014470.1	Sugar_tr	60..521	CDD:395036	95/484 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910