Protein Alignment CG14439 and sv2a

DIOPT Version :9

• Sequence 1: NP_001188550.1
• Gene: CG14439 / 31614
• FlyBaseID: FBgn0029898
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_696434.2
• Gene: sv2a / 568033
• ZFINID: ZDB-GENE-131001-1
• Length: 733
• Species: Danio rerio
• Alignment Length: 612
• Identity: 115/612 - (18%)
• Similarity: 183/612 - (29%)
• Gaps: 259/612 - (42%)

  Fly    60 NRHELPTQCSAVMNETSCYALDFNGTGYCEWN-YNGLGIDYQILAGPTFILIFTI---------- 113
            ::.||..|...::.|  |      |.|..:|. |..||:.........|::.|.:
Zfish   136 DQEELAQQYETILQE--C------GHGRFQWTLYFVLGLALMADGVEIFVVGFVLPSAEKDMCLS 192

  Fly   114 ----------------AGVFM-GFAADKYNRVNMLTVCTVIFGIAMILQGTVKEYWQLVILRMIM 161
                            .|.|: |..||:..|...|.:...|..:.......|:.|...:..|::.
Zfish   193 EPNKGMLGLIVYLGMMVGAFVWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLS 257

  Fly   162 AAGESGCNPLATGIMSDIFPEDKR--------------ALVMAIFNWGIYGGYGIAFPVGRYITK 212
            ..|..|..|:.....|:...::||              .:..|...|.|...||.:|.:|   :.
Zfish   258 GVGIGGSIPIVFSYYSEFLAQEKRGEHLSWLCMFWMIGGIYAAAMAWAIIPHYGWSFQMG---SA 319

  Fly   213 LNFWNLGWRVCYLGAGVLTV-IMAALT--------------------------GTTLRE---PER 247
            ..|.:  |||..|.....:| .:||||                          .|.:|.   |||
Zfish   320 YQFHS--WRVFVLVCAFPSVAAIAALTTMPESPRFYLENGKHDEAWMILKQVHDTNMRAKGYPER 382

  Fly   248 -------KAIGEGDRQTSSGKPVSLW-------------QVIKN--------------------- 271
                   |.:.:.|.....|...:.|             ||..|
Zfish   383 VFSVTTIKTVKQMDELVDMGGEATAWHQRWRIKLTNLFHQVWGNFLTVFNPEYRRITYMMMAVWF 447

  Fly   272 -------------PAMIMLM--------------------------------------------- 278
                         |.||..:
Zfish   448 SMSFSYYGLTVWFPDMIKYLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNKFLNLK 512

  Fly   279 ------------------IAAS---IRHCGGM-TFAYNADLY----------YNTY--------- 302
                              |.:|   .|:|..: |..||.||:          .:|:
Zfish   513 MKSMVFEDSLFEECYFEDITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNKEGCML 577

  Fly   303 -FPDVDLGWWLFGVTIGIGSVGVVVGGIVSDKIVAKMGIRSRAFVLAVSQLIATLPAFGSVYFDP 366
             |.|.:..:.::.|:. :|::.|:.|.|||..::.|:|   |..:||.|.:|:.:..|...:.:.
Zfish   578 DFSDENNAYMIYFVSF-LGTLAVLPGNIVSALLMDKIG---RLRMLAGSSVISCVSCFFLSFGNS 638

  Fly   367 LWAMITL-----GLSYFFAEMWFGIVFAIVVEIVPLRVRSSTIGVFLFVMNNIGGNLPILVDPVA 426
            ..|||.|     |:|   ...| ..:..:.||:.|...|::..| ||..:..:           |
Zfish   639 ESAMIALLCLFGGIS---IASW-NALDVLTVELYPSDKRTTAFG-FLNALCKL-----------A 687

  Fly   427 KILGYRGSIMIFYAGFYGISS---ILF 450
            .:||    |.||.: |.||:.   |||
Zfish   688 AVLG----ISIFQS-FVGITKAVPILF 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14439	NP_001188550.1	MFS_1	94..416	CDD:284993	94/538 (17%)
		MFS	107..452	CDD:119392	104/564 (18%)
sv2a	XP_696434.2	synapt_SV2	1..733	CDD:130366	115/612 (19%)
		MFS	162..725	CDD:119392	106/578 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910