Protein Alignment CG14439 and Spns1

DIOPT Version :10

• Sequence 1: NP_572347.1
• Gene: CG14439 / 31614
• FlyBaseID: FBgn0029898
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001034297.2
• Gene: Spns1 / 361648
• RGDID: 1305613
• Length: 528
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 117/549 - (21%)
• Similarity: 205/549 - (37%)
• Gaps: 149/549 - (27%)

  Fly    44 ELDYGD-HACQQNTSMFNRHELPTQCSAVMNETSCYALDFNGTGYCE-WNYNGLGID----YQIL 102
            ||:..| ...|:.|.:...|      |.::....||   .|...|.: :...|:..|    :.|.
  Rat    38 ELEVPDCEGLQRITGLSRGH------STLIVVVLCY---INLLNYMDRFTVAGVLTDIEQFFNIG 93

  Fly   103 AGPT------FILIFTIAGVFMGFAADKYNRVNMLTVCTVIFGIAMILQGTV----KEYWQLVIL 157
            .|.|      ||..:.:.....|:..|:|||..::  |..|...:::..|:.    :.:|.|::.
  Rat    94 DGSTGLIQTVFISSYMVLAPVFGYLGDRYNRKYLM--CGGIAFWSLVTLGSSFIPREHFWLLLLT 156

  Fly   158 RMIMAAGESGCNPLATGIMSDIFPEDKRALVMAIFNWGIYGGYGIAFPVGRYITKL-NFWNLGWR 221
            |.::..||:..:.:|..:::|:|..|:|:.:::||.:.|..|.|:.:..|..:..| ..|:...|
  Rat   157 RGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAGSKVKDLAGDWHWALR 221

  Fly   222 VCYLGAGVLTVIMAALTGTTLREPERKAIGEGDRQTSSG--KPVSLWQVIK----NPAMIMLMIA 280
            |. .|.|||.|::..|   .::||.|.|:   :|.:.|.  .|.|.|..:|    ||:.::..:
  Rat   222 VT-PGLGVLAVLLLFL---VVQEPPRGAV---ERHSGSPPLSPTSWWADLKALARNPSFVLSSL- 278

  Fly   281 ASIRHCGGMTFAYNADLYYNTYFPDVDLGWW------------------------------LFG- 314
                   |.|         ...|....|..|                              :||
  Rat   279 -------GFT---------AVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGDSCSSSDSLIFGL 327

  Fly   315 VTIGIGSVGVVVGGIVS----------DKIVAKMGIRSRAFVLAVSQLIATLPAFGSVYFDPLWA 369
            :|...|.:||.:|..:|          |.:|...|:...:..|.:|...|.    ||:
  Rat   328 ITCLTGVLGVGLGVEISRRLRRFNPRADPLVCAAGLLGSSPFLFLSLACAR----GSI------- 381

  Fly   370 MITLGLSYFFAEMWFGIVFAIVVEI---VPLRVRSSTIGVFLFVMNNIGGNL--PILVD------ 423
             :...:..|..|....:.:|||.:|   |.:..|.||...|..|::::.|:.  |.|:.
  Rat   382 -VATYIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAGSPYLIGLISDRL 445

  Fly   424 ----PVAKILGYRG---SIMIFYAGFYG-ISSILFFITCFLLEGKPDEVGQPESPKSHPDAVLNA 480
                |.:.:..:|.   |:|:  ..|.| :....|..|...:|.               |.....
  Rat   446 RRSWPPSFLSEFRALQFSLML--CAFVGALGGAAFLGTAMFIEN---------------DRRRAQ 493

  Fly   481 RHMHG--HDNSVFSVDETLPSNGRPAQLP 507
            .|:.|  |:.........:|..||..::|
  Rat   494 LHVQGLLHETEPSDDQIVVPQRGRSTRVP 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14439	NP_572347.1	MFS_spinster_like	67..457	CDD:340886	102/471 (22%)
Spns1	NP_001034297.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		117/549 (21%)
		MFS_spinster_like	62..479	CDD:340886	99/459 (22%)