DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ctr1A and slc31a1

DIOPT Version :9

Sequence 1:	NP_001245552.1	Gene:	Ctr1A / 31601	FlyBaseID:	FBgn0062413	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001307334.1	Gene:	slc31a1 / 403028	ZFINID:	ZDB-GENE-040415-3	Length:	188	Species:	Danio rerio

Alignment Length:	246	Identity:	89/246 - (36%)
Similarity:	121/246 - (49%)	Gaps:	65/246 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDHAHHSAPGVDHSMHHDHVGMHHDHSGIPAATASPMDAASMFDLIPDTSDLQASHAGHAAHGAH 65
            |.|:||                |.:.:.:|:               |.:.|    |.||.....:
Zfish     3 MSHSHH----------------HVEETTMPS---------------PASDD----HGGHLTTSGN 32

  Fly    66 NHGGGSGTGMEH--MMPMAFHFGY-NETILFSWWHIETVAGLIGSMIAIFLLALMYEGLKYYREY 127
            .||       :|  ||.|.|:||| |..:||:...|.|...:.|:.|.:||||::|||||..||.
Zfish    33 GHG-------DHMMMMQMTFYFGYKNVELLFAGLVINTPGEMAGACIGVFLLAVLYEGLKIGREV 90

  Fly   128 LFWKTYNLLEYR--PVTGPQRNPEAPRIPSPAAAAPSPVQYVGEVVHKQPPSMLSINHLLQTLLH 190
            |..:....:.|.  ||.|           |.........:.||:       .|||:.|.||||||
Zfish    91 LLRRNQVNVRYNSMPVPG-----------SDGTVLMETHKTVGQ-------RMLSMAHFLQTLLH 137

  Fly   191 VLQVTLSFLLMLIFMTYNVWLCLMVVLGAAVGYFLFCWKKSVIVDVTEHCH 241
            ::||.:|:.|||:|||||.:||:.|..||.:|||||.|||:|:||:|||||
Zfish   138 IIQVVVSYFLMLVFMTYNGYLCIAVAAGAGLGYFLFSWKKAVVVDITEHCH 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctr1A	NP_001245552.1	Ctr	79..226	CDD:282057	61/149 (41%)
slc31a1	NP_001307334.1	Ctr	41..173	CDD:282057	61/149 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I6967
eggNOG	1	0.900	-	-		E1_KOG3386
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1399
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4497
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1389393at2759
OrthoFinder	1	1.000	-	-		FOG0000938
OrthoInspector	1	1.000	-	-		oto41049
orthoMCL	1	0.900	-	-		OOG6_102787
Panther	1	1.100	-	-	LDO	PTHR12483
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4018
SonicParanoid	1	1.000	-	-		X3487
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.860