Protein Alignment Cdc7 and rps6kal

DIOPT Version :9

• Sequence 1: NP_727103.1
• Gene: Cdc7 / 31598
• FlyBaseID: FBgn0028360
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_956367.1
• Gene: rps6kal / 337670
• ZFINID: ZDB-GENE-030131-9616
• Length: 740
• Species: Danio rerio
• Alignment Length: 831
• Identity: 142/831 - (17%)
• Similarity: 249/831 - (29%)
• Gaps: 325/831 - (39%)

  Fly    81 EEQTV--EFNGAAVMGLPATPRT-----------------TKQARNKSEEAINDLLTRI--PDIG 124
            |.|:|  |.||..:|..|....:                 .|:...|::.:..:||..:  ...|
Zfish    15 EVQSVSSEVNGHQIMDEPMEEESYTHCDEGAYKEIPITHHVKEGCEKADPSQFELLKVLGQGSFG 79

  Fly   125 KLFDVHSRIGNGTFSTVLLGTLRRES-HLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKE 188
            |:|.|...:|........:..|::.| .:.|.:|.|......:..:||
Zfish    80 KVFLVRKLMGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHP----------------- 127

  Fly   189 NVVGIHCCMRYDASAAFVMPFMAHDRFQDFYTRMD------VPEIRQYMRNLLVALRHVHKFDVI 247
            .:|.:|...:.:.....::.|:   |..|.:||:.      ..:::.|:..|.:||.|:|...::
Zfish   128 FIVKLHYAFQTEGKLYLILDFL---RGGDVFTRLSKEVMFTEEDVKFYLAELALALDHLHNLGIV 189

  Fly   248 HRDVKPSNFLYNRRRREFLLVDFGLA-----------------QHVNPPAARSSGSA-------- 287
            :||:||.|.|.: ......|.||||:                 :::.|......|..
Zfish   190 YRDLKPENILLD-EAGHIKLTDFGLSKESVDQDKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSL 253

  Fly   288 --------AAIAAANNKNNNNNNNNNSK----RPR--ERESKGDVQQI-------ALDAGLGGA- 330
                    ........|:.|...|...|    .|:  ..|::|.::.:       .|.||..|.
Zfish   254 GVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSLEAQGLLRMLFKRNPSNRLGAGPDGVE 318

  Fly   331 -VKR---------MRLHEESNKMPLKPVN----------------------DIAPSDAPEQSVDG 363
             :||         .:|:....:.|.||.:                      .|.||....|...|
Zfish   319 EIKRHTFFSTIDWNKLYRRELQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGIPPSANAHQLFKG 383

  Fly   364 SNHVQPQLVQQEQQ----QLQPQQQQQQQQQQQQ------------------------------- 393
            .:.|.|..:::.:.    .:.|..|......|..
Zfish   384 FSFVAPVSLEESKSAPLVNILPIVQVHGSSAQFSDVYELKEDIGVGSYSICKRCIHRVTAMEFAV 448

  Fly   394 ---SQQQQQPQQQSQ-----QQHPQ---------------RQPQLAQMDQTASTPSGSKYNTNRN 435
               .:.::.|.::.:     .|||.               ...:|.:..:........|:.:.|.
Zfish   449 KIIDKSKRDPSEEIEILMRYGQHPNIITLKDVYDEGRFVYLVTELMKGGELLDKILRQKFFSERE 513

  Fly   436 VSAAAANNAKCVCFANPSVCLNC--LMKKEVHASR------AGTP-------------------- 472
            .||......|.|.:      |:|  ::.:::..|.      :|.|
Zfish   514 ASAVLYTITKTVDY------LHCQGVVHRDLKPSNILYMDDSGNPDSIRICDFGFAKQLRGDNGL 572

  Fly   473 --------GYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQ 529
                    .:..||||:: .....|.|:|:.||:..::::...||...|||  ...||:...|..
Zfish   573 LLTPCYTANFVAPEVLMR-QGYDAACDIWSLGVLLYTMLAGYTPFANGPND--TPEEILLRIGSG 634

  Fly   530 AIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCRNCDQYFFN 594
            ..                                             |:.|.     |.|..
Zfish   635 KF---------------------------------------------SLSGG-----NWDSV--- 646

  Fly   595 CLCEDSDYLTEPLDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFTAAE-----EAEQTE 654
                 ||              |:.|||..:|.::||.|.|||:.|||.:....:     :..:.|
Zfish   647 -----SD--------------SSKDLLSHMLHVDPHHRYTAEQVLKHSWIACRDQNPHFQLTRHE 692

  Fly   655 QDQLANGTPRKMRRQRYQ--SHRT-------VAAS----QEQVKQQVALDL 692
            ...|..|.    ....|.  :|:|       ||||    :..:|:..:.|:
Zfish   693 APHLVKGA----MAATYSALNHKTCKPVLEPVAASSLAQRRNMKKLTSTDM 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	117/698 (17%)
		PKc_like	<474..644	CDD:304357	37/169 (22%)
		PKc_like	<616..675	CDD:304357	18/65 (28%)
rps6kal	NP_956367.1	S_TKc	67..326	CDD:214567	53/279 (19%)
		STKc_RSK_N	71..387	CDD:270734	60/336 (18%)
		STKc_RSK4_C	415..709	CDD:271079	58/378 (15%)
		S_TKc	420..677	CDD:214567	53/337 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910