Protein Alignment Cdc7 and mapk14b

DIOPT Version :9

• Sequence 1: NP_727103.1
• Gene: Cdc7 / 31598
• FlyBaseID: FBgn0028360
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001300688.1
• Gene: mapk14b / 266756
• ZFINID: ZDB-GENE-021007-1
• Length: 361
• Species: Danio rerio
• Alignment Length: 595
• Identity: 95/595 - (15%)
• Similarity: 156/595 - (26%)
• Gaps: 299/595 - (50%)

  Fly    93 MGLPATPRTTKQARNKSEEAINDLLTRIPDIGKLFDVHSRIGNGTFSTVLLGTLRRESHLPDSLR 157
            |...|.|...:|..||:          |.::.:.:...|.:|:|.:.:|.       |.......
Zfish     1 MSQKARPTFYRQELNKT----------IWEVPERYQNLSPVGSGAYGSVC-------SAFDGKAG 48

  Fly   158 RKFAIKH----HIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDF 218
            .:.|:|.    .....|..|..:||:.:..| ..|||:|:     .|..:    |..:.:.|.|.
Zfish    49 LRVAVKKLSRPFQSIIHAKRTYRELRLLKHM-KHENVIGL-----LDVFS----PATSLEEFNDV 103

  Fly   219 Y----------------TRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLL 267
            |                .::....::..:..:|.||:::|..|:||||:||||...| ...|..:
Zfish   104 YLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRALKYIHSADIIHRDLKPSNLAVN-EDCELKI 167

  Fly   268 VDFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDAGLGGAVK 332
            :|||||                                  |..:.|..|.|
Zfish   168 LDFGLA----------------------------------RLTDDEMTGYV-------------- 184

  Fly   333 RMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQ 397
                                                                             
Zfish   185 ----------------------------------------------------------------- 184

  Fly   398 QQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKK 462
                                                                             
Zfish   185 ----------------------------------------------------------------- 184

  Fly   463 EVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMS--TVYPFFKAPNDFIALAEIVTI 525
                   .|..||.||::|.:......||:|:.|.|...:::  |::|    ..|.|...:::.:
Zfish   185 -------ATRWYRAPEIMLNWMHYNMTVDIWSVGCIMAELLTGRTLFP----GTDHIDQLKLIMM 238

  Fly   526 F----GDQAIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCR 586
            .    |.:.:.|.:....|....|....|        :..:..||..|.
Zfish   239 LVGTPGPELLMKISSESARNYISSLPHMP--------KRNFADVFIGAN---------------- 279

  Fly   587 NCDQYFFNCLCEDSDYLTEPLDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFT----AA 647
                                        |.|.|||:::|.::..|||||.:||.||:|.    ..
Zfish   280 ----------------------------PLAVDLLEKMLVLDTDKRITASQALAHPYFAQYHDPD 316

  Fly   648 EEAEQTEQDQ 657
            :|.|....||
Zfish   317 DEPEADPYDQ 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	83/544 (15%)
		PKc_like	<474..644	CDD:304357	37/175 (21%)
		PKc_like	<616..675	CDD:304357	19/46 (41%)
mapk14b	NP_001300688.1	PKc_like	7..351	CDD:304357	93/589 (16%)
		S_TKc	25..309	CDD:214567	83/542 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910