Protein Alignment Cdc7 and Cdk6

DIOPT Version :9

• Sequence 1: NP_727103.1
• Gene: Cdc7 / 31598
• FlyBaseID: FBgn0028360
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001178790.1
• Gene: Cdk6 / 114483
• RGDID: 621121
• Length: 326
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 104/554 - (18%)
• Similarity: 145/554 - (26%)
• Gaps: 279/554 - (50%)

  Fly   124 GKLFDVHSRIGNGTFSTVLLGTLR---RESHLPDSLRRKFAIKHHIPT-SHPDRIMKELQCMTKM 184
            ||:|........|.|  |.|..:|   .|..:|.|..|:.|:..|:.| .||
  Rat    25 GKVFKARDLKNGGRF--VALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHP------------- 74

  Fly   185 GGKENVVGIH--CCM-RYDASAAFVMPFMAHDRFQDFYTRMD-VPE-------IRQYMRNLLVAL 238
                |||.:.  |.: |.|......:.|...|  ||..|.:| |||       |:..|..||..|
  Rat    75 ----NVVRLFDVCTVSRTDRETKLTLVFEHVD--QDLTTYLDKVPEPGVPTETIKDMMFQLLRGL 133

  Fly   239 RHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNN 303
            ..:|...|:|||:||.|.|.. ...:..|.|||||
  Rat   134 DFLHSHRVVHRDLKPQNILVT-SSGQIKLADFGLA------------------------------ 167

  Fly   304 NNSKRPRERESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQ 368
                                           |::  |.:|.|..|
  Rat   168 -------------------------------RIY--SFQMALTSV-------------------- 179

  Fly   369 PQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTN 433
                                                                             
  Rat   180 ----------------------------------------------------------------- 179

  Fly   434 RNVSAAAANNAKCVCFANPSVCLNCLMKKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVI 498
                                               ..|..||.|||||: ....|.||:|:.|.|
  Rat   180 -----------------------------------VVTLWYRAPEVLLQ-SSYATPVDLWSVGCI 208

  Fly   499 FLSIMSTVYPFFKAPNDFIALAEIVTIFG--DQAIRKTALALDRMITLSQRSRPLNLRKLCLRFR 561
            |..:... .|.|:..:|...|.:|:.:.|  .:......:||.|....|:.::|:.      :|
  Rat   209 FAELFRR-KPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIE------KF- 265

  Fly   562 YRSVFSDAKLLKSYESVDGSCEVCRNCDQYFFNCLCEDSDYLTEPLDAYECFPPSAYDLLDRLLE 626
                                               ..|.|.|.:             |||.:.|.
  Rat   266 -----------------------------------VTDIDELGK-------------DLLLKCLT 282

  Fly   627 INPHKRITAEEALKHPFFTAAEEAEQTEQDQLAN 660
            .||.|||:|..||.||:|...|..:......|::
  Rat   283 FNPAKRISAYGALNHPYFQDLERYKDNLHSHLSS 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	100/535 (19%)
		PKc_like	<474..644	CDD:304357	43/171 (25%)
		PKc_like	<616..675	CDD:304357	17/45 (38%)
Cdk6	NP_001178790.1	STKc_CDK6	11..300	CDD:270846	101/536 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910