DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc7 and dmpk

DIOPT Version :9

Sequence 1:	NP_727103.1	Gene:	Cdc7 / 31598	FlyBaseID:	FBgn0028360	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	XP_009303323.1	Gene:	dmpk / 101886625	-ID:	-	Length:	600	Species:	Danio rerio

Alignment Length:	181	Identity:	40/181 - (22%)
Similarity:	66/181 - (36%)	Gaps:	60/181 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 RTTKQARNKSEEAINDLLTRIPDIGKLFDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFAIKH 164
            |..|:.|...|:               |.:...||.||||.|.|..:|       :.::.:|:|
Zfish    67 RQVKKTRISRED---------------FHILKVIGRGTFSEVALARMR-------NTQQVYAVK- 108

  Fly   165 HIPTSHPDRIMK--------ELQCMTK------MGGKENVVGIHCCMRYDASAAFVMPFMAH--- 212
                     ||.        |:.|..:      .|.:..:..:|...:.|.....||.:...
Zfish   109 ---------IMNKWDMLKRGEMACYQEEREVLLKGDRRWITELHYAFQDDDYLYLVMHYYVGGDL 164

  Fly   213 ----DRFQDFYTRMDVPE--IRQYMRNLLVALRHVHKFDVIHRDVKPSNFL 257
                .:|.|     .:||  .:.|:..:::|:..||....:|||:||.|.|
Zfish   165 LTLLSKFND-----GLPEEMAQFYLAEMVMAIDSVHLLGYVHRDIKPDNIL 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	36/156 (23%)
		PKc_like	<474..644	CDD:304357
		PKc_like	<616..675	CDD:304357
dmpk	XP_009303323.1	PKc_like	77..406	CDD:304357	37/171 (22%)
		S_TKc	79..344	CDD:214567	36/154 (23%)
		bZIP	<482..513	CDD:304365
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910