Protein Alignment Cdc7 and cdk13

DIOPT Version :9

• Sequence 1: NP_727103.1
• Gene: Cdc7 / 31598
• FlyBaseID: FBgn0028360
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_002940845.2
• Gene: cdk13 / 100489599
• XenbaseID: XB-GENE-6040279
• Length: 1391
• Species: Xenopus tropicalis
• Alignment Length: 608
• Identity: 114/608 - (18%)
• Similarity: 182/608 - (29%)
• Gaps: 284/608 - (46%)

  Fly   100 RTTKQARNKSEEAI-----NDLLTRIPDIGK----LFDVHSRIGNGTF------------STVLL 143
            |...|:|||....|     .::|.:..|.||    .||:...||.||:            ..|.|
 Frog   562 RKKNQSRNKRRPKICGPRCGEILEKEIDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGEMVAL 626

  Fly   144 GTLRRESH---LPDSLRRKFAIKHHIPTSHPDRI-MKELQCMTKMGGKENVVGIHCCMRYDASAA 204
            ..:|.::.   .|.:..|:..|...:  :|...| |||:     :..||:.:.    .:.|..|.
 Frog   627 KKVRLDNEKEGFPITAIREIKILRQL--NHQSIINMKEI-----VTDKEDALD----FKKDKGAF 680

  Fly   205 F-VMPFMAHD---RFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREF 265
            : |..:|.||   ..:......:...|:.:||.|:..|.:.||.:.:|||:|.||.|.| .|.:.
 Frog   681 YLVFEYMDHDLMGLLESGLVHFNEHHIKSFMRQLMEGLDYCHKRNFLHRDIKCSNILLN-NRGQI 744

  Fly   266 LLVDFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDAGLGGA 330
            .|.|||||
 Frog   745 KLADFGLA--------------------------------------------------------- 752

  Fly   331 VKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQ 395
                ||:                                                        |.
 Frog   753 ----RLY--------------------------------------------------------SS 757

  Fly   396 QQQQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLM 460
            ::.:|.                              ||:.:
 Frog   758 EESRPY------------------------------TNKVI------------------------ 768

  Fly   461 KKEVHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTI 525
                      |..|||||:||.....:.|:|||:.|.| |..:.|..|.|:| |..:|..|:::
 Frog   769 ----------TLWYRPPELLLGEERYSPAIDVWSCGCI-LGELFTKKPIFQA-NQELAQLELIS- 820

  Fly   526 FGDQAIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCRNCDQ 590
                                         ::| .....:|:.|...|.
 Frog   821 -----------------------------RMC-GSPCPAVWPDVIKLP----------------- 838

  Fly   591 YFFNCLCEDSDYLTEPLDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFTAAEEAEQTEQ 655
             :||.:.....|..:..:.:...|.:|.||.|.:|.::|:||.|||:||...|....:.::.|..
 Frog   839 -YFNTMKPKKQYRRKLREEFVFIPNAALDLFDHMLALDPNKRCTAEQALLCEFLRDVDPSKMTPP 902

  Fly   656 D--------QLANGTPRKMRRQR 670
            |        :|.:   :|.|||:
 Frog   903 DLPLWQDCHELWS---KKRRRQK 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	97/542 (18%)
		PKc_like	<474..644	CDD:304357	42/169 (25%)
		PKc_like	<616..675	CDD:304357	21/63 (33%)
cdk13	XP_002940845.2	STKc_CDK12	590..891	CDD:270847	98/544 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910