Protein Alignment CG14443 and ddx3xa

DIOPT Version :10

• Sequence 1: NP_572330.2
• Gene: CG14443 / 31595
• FlyBaseID: FBgn0029880
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: XP_021334401.1
• Gene: ddx3xa / 566947
• ZFINID: ZDB-GENE-030131-1565
• Length: 841
• Species: Danio rerio
• Alignment Length: 710
• Identity: 169/710 - (23%)
• Similarity: 285/710 - (40%)
• Gaps: 170/710 - (23%)

  Fly    73 GIEGQKPNFKIRSESFSGPHSAGGFSKS-TRESRSKSRSMGNGKFRGKSHLRSSSESAHSSG--- 133
            |.:|.:.|..:.....|..:....|::. .|..|.     |.|.|||..:..|.::..|::|
Zfish   184 GWDGSRTNGFVNGYHDSRMNGTANFARGPLRNDRG-----GRGGFRGNRNGASFNQPVHNAGYGT 243

  Fly   134 SESSSSDSNSGSSSDSDSTTGSSSHGSDTGERPRMRSAVFRIHETWQSPNSFKAVKTSRENKESR 198
            .|:.....||..:.|:.::.|        |...|.:||.|
Zfish   244 YENKDGGWNSVVNRDAYASFG--------GRSDRGKSAFF------------------------- 275

  Fly   199 SRSSSLPQKRFCPSKTQNDLTYGSPEPKSPSNRGRN-----SWRVGMRTPWKKSQSRSMSCSSIQ 258
                             ||        :..|:|||.     ....|..:.|.: :||
Zfish   276 -----------------ND--------RGASSRGRYERGGFGGGTGGNSRWVE-ESR-------- 306

  Fly   259 KILVSRSFTRSRSPHRNTLCYQDQSKNPSRPSNYNTWKQPM-------DEVY---NNAANYRKRH 313
                                            :...|.:||       .|::   |...|:.|..
Zfish   307 --------------------------------DEEDWSKPMPPNERLEHELFSASNTGINFEKYD 339

  Fly   314 NITLTSWNMRNLPEPVLSFERSGFNATILQQLEDQGYDGPTPIQAQTWSIAKEGKNIVMISGKGT 378
            :|.:.:.. .|.|..:.||........|:..:....|..|||:|.....|.|..::::..:..|:
Zfish   340 DIPVEATG-TNSPGHIESFHDVDMGEIIMGNITLSRYTRPTPVQKYAIPIIKTKRDLMACAQTGS 403

  Fly   379 GKTLGYLLPGIMKMHNQ---------RGLMQHKKG--------PIVLILVDCREAAVMVQREVLY 426
            |||..:|||.:.:::::         :...|.:.|        ||.|:|...||.|:.:..|...
Zfish   404 GKTAAFLLPVLSQIYSEGPGEALQATKASTQQENGKYVRRKQYPISLVLAPTRELALQIYDEARK 468

  Fly   427 YTNPLELRTHCLLGNSQWQGHAE-----CDLLVASAGRLLQMIDNKKHVVELERCTYLVLDNIDR 486
            :.....:|...:.|.:.......     |.||||:.|||:.|::..|  :.|:.|.|||||..||
Zfish   469 FAYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK--IGLDYCKYLVLDEADR 531

  Fly   487 MIDVGLEGNICRLLCR--LRPHA--QLIVSSTSWSSNLKRMANKFLGQYTAIRVGEINNIGVRLQ 547
            |:|:|.|..|.|::.:  :.|..  |.::.|.::...::.:|..||.:|..:.||   .:|...:
Zfish   532 MLDMGFEPQIRRIVEQDTMPPKGSRQTMMFSATFPKEIQILARDFLEEYIFLAVG---RVGSTSE 593

  Fly   548 NIRQRVEVVNGLSKVERLMKELTAIYDTSDIPGK---VVIYVKRQKVVEELVD-LIRNCVPCEGI 608
            ||.|:|..|....|...|:..|.|       .||   .:::|:.:|..:.|.| |.|....|..|
Zfish   594 NITQKVVWVEENDKRSFLLDLLNA-------TGKDSLTLVFVETKKGADALEDFLYREGYACTSI 651

  Fly   609 HGGRTAQENQGIIHDFGTGAYNIIVATQMTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRTGCLS 673
            ||.|:.::.:..:|.|.:|...|:|||.:.:..||:..:::|||:|.|.:|::||.|:.|||.:.
Zfish   652 HGDRSQRDREEALHQFRSGRCPIMVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVG 716

  Fly   674 YNRNCEVISFFTMANYKLVTEVVDFLKICKQEIGPHLLQLAEEKMFGPRQRRRHRPQRYN 733
             |... ..||:...|..:..:::|.|...|||:...|..||.|...  :...|.||:|::
Zfish   717 -NLGL-ATSFYNDKNSNITKDLLDILVEAKQEVPSWLENLAYEHQH--KSTNRGRPKRFS 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14443	NP_572330.2	DEAD-like_helicase_N	<310..720	CDD:475120	124/439 (28%)
ddx3xa	XP_021334401.1	DEADc_DDX3	335..590	CDD:350809	67/260 (26%)
		SF2_C_DEAD	595..725	CDD:350174	44/138 (32%)