Protein Alignment CG3842 and CBR3

DIOPT Version :10

• Sequence 1: NP_572316.1
• Gene: CG3842 / 31576
• FlyBaseID: FBgn0029866
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001227.1
• Gene: CBR3 / 874
• HGNCID: 1549
• Length: 277
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 74/281 - (26%)
• Similarity: 109/281 - (38%)
• Gaps: 71/281 - (25%)

  Fly    75 KVVIVTGCNTGIGKETVLELAKR-GARVYMACRDPGRCEAARLDIMDRSRNQQLFNRTLDLGSLQ 138
            :|.:|||.|.|||.....||.:: ...|.:..||..|.:||...:.....:.:.  ..||:..||
Human     6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRF--HQLDIDDLQ 68

  Fly   139 SVRNFVERFKAEESRLDILINNAGVM-----ACPRTLTADGFEQQFGVNHLGHFLLTNLLLDRLK 198
            |:|...:..:.|...|::|:|||.|.     ..|..:.|   |.....|......:.|.||..:|
Human    69 SIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKA---EMTLKTNFFATRNMCNELLPIMK 130

  Fly   199 -HSSPSRIVVVSSAAHLFGRINREDLMSEKNYS-------------KFF---------------G 234
             |   .|:|.:||...|....|..:.:.|:.:|             ||.               .
Human   131 PH---GRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNS 192

  Fly   235 AYSQSKLANILFTLKLSTIL--------KDTGVTVNCCHPGVVRTEINRHFSGPGWMKTALQKGS 291
            .|..|||.    ...||.||        |...:.||.|.||.|:|:::             .|.|
Human   193 PYGVSKLG----VTVLSRILARRLDEKRKADRILVNACCPGPVKTDMD-------------GKDS 240

  Fly   292 LYFFKTPKAGAQTQLRLALDP 312
            :   :|.:.||:|.:.|||.|
Human   241 I---RTVEEGAETPVYLALLP 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_572316.1	Rossmann-fold NAD(P)(+)-binding proteins	74..347	CDD:473865	74/281 (26%)
CBR3	NP_001227.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	74/281 (26%)