Protein Alignment CG3842 and HSD17B13

DIOPT Version :10

• Sequence 1: NP_572316.1
• Gene: CG3842 / 31576
• FlyBaseID: FBgn0029866
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_835236.2
• Gene: HSD17B13 / 345275
• HGNCID: 18685
• Length: 300
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 67/263 - (25%)
• Similarity: 113/263 - (42%)
• Gaps: 52/263 - (19%)

  Fly    41 VLIFLIVLGILLFMWLLRKCIQG--PAYRKANRIDGKVVIVTGCNTGIGKETVLELAKRGARVYM 103
            :::.:::|.|.:....|...::.  |..||:  :.|::|::||...|||::|..|.|||.:.:.:
Human     3 IILEILLLLITIIYSYLESLVKFFIPQRRKS--VAGEIVLITGAGHGIGRQTTYEFAKRQSILVL 65

  Fly   104 -------------ACRDPGRCEAARLDIMDRSRNQQLFNRTLDLGSLQSVRNFVERFKAEESRLD 155
                         .||..|  ..|...::|.|..::::.      ||..|       |.|...:.
Human    66 WDINKRGVEETAAECRKLG--VTAHAYVVDCSNREEIYR------SLNQV-------KKEVGDVT 115

  Fly   156 ILINNAGVMACPRTLTADGFEQ---QFGVNHLGHFLLTNLLLDRLKHSSPSRIVVVSSAAHLFGR 217
            |::||||.: .|..|.:...|:   .|.||.||||.:|..||..:...:...||.|:|..
Human   116 IVVNNAGTV-YPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVC----- 174

  Fly   218 INREDLMSEKNYSKFFGAYSQSKLANILFTLKLSTILK---DTGVTVNCCHPGVVRTEINRHFSG 279
             ..|.:       .:...|..||.|.:.|...|::.|:   .||:..:|..|..|.|...::.|.
Human   175 -GHEGI-------PYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPST 231

  Fly   280 PGW 282
            ..|
Human   232 RLW 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_572316.1	Rossmann-fold NAD(P)(+)-binding proteins	74..347	CDD:473865	61/228 (27%)
HSD17B13	NP_835236.2	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	60/226 (27%)