Protein Alignment CG3842 and Hsd17b13

DIOPT Version :10

• Sequence 1: NP_572316.1
• Gene: CG3842 / 31576
• FlyBaseID: FBgn0029866
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001009684.1
• Gene: Hsd17b13 / 305150
• RGDID: 1359553
• Length: 300
• Species: Rattus norvegicus
• Alignment Length: 265
• Identity: 69/265 - (26%)
• Similarity: 114/265 - (43%)
• Gaps: 57/265 - (21%)

  Fly    41 VLIFLIVLGILLFMWL--LRKCIQGPAYRKANRIDGKVVIVTGCNTGIGKETVLELAKRGARVYM 103
            :|..|:::||:::.:|  |.|... |..||:  :.|:.|::||...|||:.|..|.||:.:|:.:
  Rat     4 ILELLLLVGIIIYSYLESLVKFFI-PQRRKS--VAGQTVLITGAGHGIGRLTAYEFAKQKSRLVL 65

  Fly   104 -------------ACRDPGRCEAARLDIMDRSRNQQLFNRTLDLGSLQSVRNFVERFKAEESRLD 155
                         .||..|  ....:.::|.|...:::..             |::.|.|...::
  Rat    66 WDISKHGVEETAAKCRKLG--AVVHVFVVDCSNRAEIYKS-------------VDQVKKEVGDIE 115

  Fly   156 ILINNAGVMACPRTLTADGFEQ---QFGVNHLGHFLLTNLLLDRLKHSSPSRIVVVSS-AAHLFG 216
            |::||||.: .|..|.:...|:   .|.||.||||.:...||..:...:...||.|:| ..|
  Rat   116 IVVNNAGAI-YPADLLSTKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGH--- 176

  Fly   217 RINREDLMSEKNYSKFFGAYSQSKLANILF----TLKLSTILKDTGVTVNCCHPGVVRTEINRHF 277
                       ....:...|..||.|.:.|    |.:|.|:.| ||:..:|..|..|.|...::.
  Rat   177 -----------RVIPYLIPYCSSKFAAVGFHRALTAELDTLGK-TGIKTSCLCPVFVNTGFTKNP 229

  Fly   278 SGPGW 282
            |...|
  Rat   230 STRLW 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3842	NP_572316.1	Rossmann-fold NAD(P)(+)-binding proteins	74..347	CDD:473865	59/230 (26%)
Hsd17b13	NP_001009684.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	58/228 (25%)