Protein Alignment CG3815 and phf12a

DIOPT Version :10

• Sequence 1: NP_572311.1
• Gene: CG3815 / 31571
• FlyBaseID: FBgn0029861
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_001919955.5
• Gene: phf12a / 562152
• ZFINID: ZDB-GENE-030131-3876
• Length: 941
• Species: Danio rerio
• Alignment Length: 982
• Identity: 283/982 - (28%)
• Similarity: 425/982 - (43%)
• Gaps: 219/982 - (22%)

  Fly     7 DPNASLSIMEQIKQLIRPPPNED----EKMMQRSTNTKHPYYRRPGRGHNHDYCDACEEGGNLLC 67
            |.:.|..:||:|:.|:.||.:||    .:...|||       ||.||..|||.||:|.|||:|||
Zfish    13 DLDTSGGLMEKIQTLLAPPKSEDGEKKNRKPDRST-------RRSGRATNHDICDSCREGGDLLC 70

  Fly    68 CDRCPSSFHLQCHDPPLSEEDIPSGQWLCHSC--------------------RMSKLSQPPASSS 112
            ||.||::|||||.:||||.|.:|||.|:||.|                    ::.|.:.|||...
Zfish    71 CDHCPAAFHLQCCNPPLSREMLPSGDWMCHRCTVRKKKREQKKEQINGLLERQLGKQTPPPAPEQ 135

  Fly   113 KASSVERVPSAGSGSRANTPSSGDLESIPLKIRNLRKR---------SN---------SERNSTE 159
            ...::...||.|:|...       |.:...::|.|.:|         ||         ||:|.||
Zfish   136 DCGTLRLDPSVGTGGTG-------LRAAVAQVRLLERRHSSRPATPNSNTSSADTPTPSEQNDTE 193

  Fly   160 KLLAKMPMSIQRALDPNKKPT------PLDDVIRAATMMNPQQFSLPPELELHTQFPGNGKVQPV 218
            :.|..:....|.: :|....|      |.|.:|.||...||.||.||.:|...|..||..|
Zfish   194 EDLLDVEDETQGS-EPELSNTTTTLKRPFDLLIAAAMQRNPTQFQLPNDLTCTTALPGTSK---- 253

  Fly   219 QQTHPPSGNGGNRRCAGNQRRNSKP-FELDAQGLVPLPAKTCFYCTRSCKRAPLISCDYCPLYFH 282
                      ..|:...:.:...:| .|||:.||||||.|.|:.|:|||:.||||.||:|||.||
Zfish   254 ----------RRRKDELSSKSVKRPQHELDSCGLVPLPVKVCYTCSRSCRLAPLIQCDFCPLLFH 308

  Fly   283 QDCLDPPLTALPAGLWMCPNHAENFIDANMTNSISATERVRLWNRFHQPLDHENVKLEFFRRVNT 347
            .|||||||||.|.|.||||||.:|.| .|. .|::.:.|.:|:::|...:....|||:|.:|::.
Zfish   309 MDCLDPPLTAFPTGRWMCPNHIQNLI-LNQ-RSLTISNRCQLFDQFQDCISQHAVKLDFLQRIHR 371

  Fly   348 RNPPFRTKRNLRARAHIEVPAIVRYHYDHPPPLLPSMRQTLRYDRVKRRNNLPTEVEE------I 406
            ::||.:...:.|::..::||..::..|.:||.|:.|.       .|:....:.|.:.|      :
Zfish   372 QHPPIQRSTHARSKKTLKVPDAIKSQYQNPPTLMASA-------GVREGELICTGLPEASVPQHL 429

  Fly   407 SRESVTESLLKDLEALR----------------TAHAKFREIQREFGTLETAIDGDSDSDPS-PE 454
            :.|......|||:.:|:                :.|.:..:::........|..|..:|.|. |.
Zfish   430 ASEDEQHQWLKDIISLQCSIMRHLRNRQTSHWDSEHTEKTDLKLRDSCQSAASQGSQNSSPKVPC 494

  Fly   455 EKRTE--------TNTPADKVNGEVDTENP-NTESNAQASEQPSVVKVESKTSLEVEASFEEDEE 510
            ...||        ||.|.|:......|::| .|::.:...|:|.:............|..:.::.
Zfish   495 SSCTEGLCQNCKTTNGPVDQSIQSNGTQDPVRTQNKSADREKPCLPMPSPPNHANSGAIIKGEDA 559

  Fly   511 DSKKSTGIIDADLLHLDVDIIKKLAHQRLQQLVEEHPEIVTQYKNRT-----AARRLRQLASVDG 570
            ..|..:|          .|::.. ||      |:..|........:|     ||.::.......|
Zfish   560 SLKPRSG----------TDVLPP-AH------VKSEPRTQPCDHAKTPPASDAAAKVSDSTVCTG 607

  Fly   571 THV-----AGETAALQGQLAPEDM--NRFSL--------LFTSETSSILAQKNGNAAD------E 614
            .|.     ....|...||.:|...  .:.||        ..:|.|...:::.:|...|      |
Zfish   608 AHAVKPQKVTSDAGSNGQRSPSSSCGGKSSLDSVMAGSGDISSCTEPNMSELSGRIKDIMQGGGE 672

  Fly   615 DPATALHPALATAAAIAAADAAAESYAPRARSDTEKAYELASRLELKLLQCKVQARAVITPLGDM 679
            ....||........|........:|.:...:|.:..:...|.|...:....:|||||.
Zfish   673 VELNALDEKFIKLLAWQRIQQLFDSKSSPVQSSSPLSVSPAHRKHGEAQNREVQARAS------- 730

  Fly   680 LEDSRWFSSLGLDHSIFMRYRTLYIGYGGHYSPSTTLAQTETVDLSAIGYCCRISPQHAIIFYDE 744
                  |.|:. .:::.|.||:|:||.|....          |.|:..|:|..:|.:||.|||||
Zfish   731 ------FCSVS-GNAVNMCYRSLHIGTGADMD----------VCLTNYGHCNYVSGKHACIFYDE 778

  Fly   745 FSKSYELINYSEFGTEVNGQLYACDVTERMTTHAGKPMRPDDAELKKRVDEMLDKRRNINRQFET 809
            .:|.|||:||||.||.|:..||:||.:|:|:              :.....:|.|.:||.|:...
Zfish   779 NTKQYELLNYSEHGTTVDNILYSCDFSEKMS--------------QSPSSNLLTKVQNIIRRCRK 829

  Fly   810 K-KIDKERLAPIVKPA--------------CRCMNAGPVPMVDGA---WEGSAVLAHGSLLRFGC 856
            | :.|.....|..|..              |.|.|:|. .|:.|:   |||:|:|.|||.::.||
Zfish   830 KEQEDSLNSVPSAKEVTHMSCQSQDASVTPCNCKNSGS-RMIGGSGAGWEGTALLHHGSHVKLGC 893

  Fly   857 LSFVFVV 863
            |.|:|.:
Zfish   894 LQFIFSI 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3815	NP_572311.1	PHD1_PHF12	55..99	CDD:277008	29/43 (67%)
		BAH	75..198	CDD:470629	48/166 (29%)
		PHF12_MRG_bd	175..211	CDD:465250	15/41 (37%)
		PHD2_PHF12_Rco1	259..303	CDD:277009	31/43 (72%)
		FHA	667..861	CDD:469597	70/211 (33%)
phf12a	XP_001919955.5	None