Protein Alignment mldr and Prorp

DIOPT Version :10

• Sequence 1: NP_572309.2
• Gene: mldr / 31568
• FlyBaseID: FBgn0029858
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_079649.1
• Gene: Prorp / 66132
• MGIID: 1913382
• Length: 584
• Species: Mus musculus
• Alignment Length: 548
• Identity: 149/548 - (27%)
• Similarity: 251/548 - (45%)
• Gaps: 53/548 - (9%)

  Fly     9 NLLPIAGHAH-------------PRWLAS-QHKRRPQPGSLPADRLDQL--RSDLFERRHELSGA 57
            |||......|             |.:.|: ..|:|...|:.|.::...|  ||.:......|:.|
Mouse    58 NLLDTKARTHRKGNDNNGQVSSDPHYFAAGAAKKRSHIGANPQNQGHALPVRSSVQLPTKPLNSA 122

  Fly    58 EWTEVRRSLVDGYKHINGHNVDAVILGVCSAPNQLSLAKSYVEFLRSRGSKPNAATLGRLLRV-- 120
            ||.:::... .|........:..:....||    :.:|||.:.::.::    |...:|..|.|
Mouse   123 EWDKLKEDF-KGKASFEDFIISQMARNCCS----VDVAKSLLAWVAAK----NNGIVGYNLLVKY 178

  Fly   121 -YNAAYHERPLSEAEQSEILQICRSLQAEHETLDASSCENVIHGLVATSGDDWQRGLPLLEMMKV 184
             |...:|:      :.||::.:...::|::::|::.....:|.||:  ..|.|:..|.|||.:|.
Mouse   179 LYLCVFHK------QTSEVIDVYEIMKAKYKSLESGGYTLLIRGLI--HSDRWRESLLLLEDIKK 235

  Fly   185 TSTPSVAAYSALAEKAFSVATPEQELAWRLLEEMATARKPPKCEVYLALLN--RLANETAQLPAQ 247
            ...||...|....:.|  :...:...||.|.:|:......|..|...|..:  :..|:.......
Mouse   236 VMVPSKKNYGDCIQGA--LLHQDVNTAWNLYQELIGHNLIPPLETLKAFFDYGKDINDDHYSDKL 298

  Fly   248 LSLLLQFLERHEILVSQRVAIRLQELSSQVP-QLLHTRTTHLGGLGKCQSCQQHLQPVAISDEEF 311
            |.:|| :|..:::...:..|..::.....:| :....:.|.:...|:|..|.:.::|:.:|.||:
Mouse   299 LDILL-YLRNNQLYPGESFAHSIKTWFESIPGRQWKGQFTTIQKSGQCSGCGRTIEPIHLSPEEY 362

  Fly   312 RQLSECFLERVLIRRDVFQRSTPEEVARFKKFVEKTAPYDCVIDGLNVAYSTGTKKTPQQLAKLV 376
            ..|.|..:..|:...|.::::||:|:.||:.||....|:|.||||||||......:..|.|
Mouse   363 EFLKEKIMRDVIDGGDQYKKTTPQELKRFESFVNSCPPFDIVIDGLNVAKMFPKGRESQNL---- 423

  Fly   377 ATVVRHFREQDKRVLVLGREHM----RNWSKQAMHYVHCNASLFLTSNLSHDDPFLLYATLRSGQ 437
            ..||....:|:.::|||||:||    ..|.|:.|..|...|..|...|:|.||||||||||.||.
Mouse   424 LGVVSQLAQQNLQLLVLGRKHMLRPSSQWRKEEMEQVRKQAHCFFADNISEDDPFLLYATLNSGN 488

  Fly   438 ETDFFSRDLMRSHAFHL-GTELKPIFRRWQQEHQFSLVTQTQTGQIIVKEPVRHRLCAHQVADTW 501
            ...|.::||:|.|...| ....:.:|.:|||.||.:::...|..::..:..:.:.....:..|:|
Mouse   489 HCKFITKDLLRDHKACLPDARTQRLFFKWQQGHQLAIMKGFQKSKLTFQHILSYDTVVQRTGDSW 553

  Fly   502 HVPYCAQYTPHPTDSFEVPANWLCIQMK 529
            |:||.......  .|.|||..|||:|.|
Mouse   554 HIPYDEDLVQR--SSCEVPTKWLCLQRK 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mldr	NP_572309.2	PRORP	288..525	CDD:465320	83/241 (34%)
Prorp	NP_079649.1	PPR repeat	170..201	CDD:276811	7/36 (19%)
		PPR repeat	207..235	CDD:276811	9/29 (31%)
		PRORP	339..575	CDD:465320	83/241 (34%)