Protein Alignment mldr and prorp

DIOPT Version :10

• Sequence 1: NP_572309.2
• Gene: mldr / 31568
• FlyBaseID: FBgn0029858
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_683289.3
• Gene: prorp / 555630
• ZFINID: ZDB-GENE-100618-4
• Length: 578
• Species: Danio rerio
• Alignment Length: 541
• Identity: 144/541 - (26%)
• Similarity: 244/541 - (45%)
• Gaps: 74/541 - (13%)

  Fly    14 AGHAHPRWLASQHKR-------------RPQPGSLPADRLDQLRSDLFERRHELSGAEWTEVRR- 64
            ||.|..|....:||.             |..|..:..||             .|:.:|||.:::
Zfish    81 AGAARKRAEFLKHKSGLDTENDDTPVRVRDSPNMVLPDR-------------PLTPSEWTNLKKD 132

  Fly    65 -SLVDGYKHINGHNVDAVILGVCSAPNQLSLAKSYVEF-LRSRGSKPNAATLGRLLRVYNAAYHE 127
             |..:.::.:...|       :..|...:::|||.:.: ::.:|:......|..|.....|.:|
Zfish   133 FSRPELFEKVMMEN-------LVRANVDVNIAKSLLSYVVQDKGTLSYEILLRYLTICVRAGHH- 189

  Fly   128 RPLSEAEQSEILQICRSLQAEHETLDASSCENVIHGLVATSGDDWQRGLPLLEMMKVTSTPSVAA 192
                    ||:......:::..::||..:....|.|...|  |.|:..:.:|:.||....||...
Zfish   190 --------SEVFDAYDIMRSCFKSLDLGASALFIKGFSQT--DRWKEAISMLQDMKKALLPSPRN 244

  Fly   193 YSALAEKAFSVATPEQELAWRLLEEMATARKPPKCEVYLAL----LNRLANETAQLPAQLSLLLQ 253
            |..:.  |.:|...:.|.:|:|.:|:......|..:.:..|    :.:..:|.     :|..:|.
Zfish   245 YGDVI--AGAVLHGDSETSWKLYDELLELGLVPGQDTWQCLFQSGITQRGHED-----KLFDVLS 302

  Fly   254 FLERHEILVSQRVAIRLQELSSQVP-QLLHTRTTHLGGLGKCQSCQQHLQPVAISDEEFRQLSEC 317
            ::..::|...:.:...::.....:| |....:.:.:...|.|::|:..|:.:.:::.|:.||...
Zfish   303 YMRDNQIYPEKPLMETIKAWFESLPDQKWRGKFSSVTPSGDCRNCKALLESIQLTEVEYAQLKHN 367

  Fly   318 FLERVLIRRDVFQRSTPEEVARFKKFVEKTAPYDCVIDGLNVAYSTGTKKTPQ--QLAKLVATVV 380
            .:|:|:...|||.:|.|||:..||.||::..|:|.||||||||     |..|.  |...|:| ||
Zfish   368 VMEKVIEGGDVFNKSNPEELKSFKSFVKQRPPFDIVIDGLNVA-----KMLPHAAQSETLLA-VV 426

  Fly   381 RHFREQDKRVLVLGREHM----RNWSKQAMHYVHCNASLFLTSNLSHDDPFLLYATLRSGQETDF 441
            ....:|...:|||||:||    |||.:|.|..:...|..|.|.::|.|||:||||.|.||....|
Zfish   427 SELEQQSLNILVLGRKHMLRHSRNWDRQNMSLIKQKAHCFFTEDISEDDPYLLYAALNSGVHCKF 491

  Fly   442 FSRDLMRSHAFHL-GTELKPIFRRWQQEHQFSLVTQTQTGQIIVKEPVRHRLCAHQVADTWHVPY 505
            .||||||.|...| .:..:.:|.:||:.||..:...|...::..:..:.:.........:||:||
Zfish   492 LSRDLMRDHKACLPDSATRCLFFKWQRGHQLVISHYTPGKRVRFERILSYDTIIQTNGSSWHIPY 556

  Fly   506 CAQYTPHPTDSFEVPANWLCI 526
              ........|:|||..|||:
Zfish   557 --DQKAEDRASYEVPQKWLCL 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mldr	NP_572309.2	PRORP	288..525	CDD:465320	88/243 (36%)
prorp	XP_683289.3	PPR repeat	172..202	CDD:276811	6/38 (16%)
		PPR repeat	215..237	CDD:276811	8/23 (35%)
		PPR repeat	242..271	CDD:276811	7/30 (23%)
		PPR repeat	277..307	CDD:276811	4/34 (12%)
		PRORP	338..574	CDD:465320	88/243 (36%)