DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rpt4 and AFG3

DIOPT Version :10

Sequence 1:NP_572308.3 Gene:Rpt4 / 31567 FlyBaseID:FBgn0028685 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_010933.1 Gene:AFG3 / 856737 SGDID:S000000819 Length:761 Species:Saccharomyces cerevisiae


Alignment Length:257 Identity:97/257 - (37%)
Similarity:142/257 - (55%) Gaps:17/257 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 VTYSAIGGLTDQIRELREVIELPLLNPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDAN 202
            :::..:.|..:..:|:.|.:.. |.||..:.::|...|:|.:|.|||||||||||:|.|.:.:..
Yeast   285 ISFKNVAGCDEAKQEIMEFVHF-LKNPGKYTKLGAKIPRGAILSGPPGTGKTLLAKATAGEANVP 348

  Fly   203 FLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGT--SADREIQRTL 265
            ||.|..|..|:.::|..|..:|::|..||...|.|||:|||||||..|...|.  .|:.|.:.||
Yeast   349 FLSVSGSEFVEMFVGVGASRVRDLFTQARSMAPSIIFIDEIDAIGKERGKGGALGGANDEREATL 413

  Fly   266 MELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQARLEILKIHALKIAK 330
            .:||.:||||.:..||.::..|||||.||.||:||||.||.|:|..|:...|.:|..:|..::  
Yeast   414 NQLLVEMDGFTTSDQVVVLAGTNRPDVLDNALMRPGRFDRHIQIDSPDVNGRQQIYLVHLKRL-- 476

  Fly   331 HGEID----------YEAIVKLSDNFNGADLRNVCTEAGLFAIRAEREYVIQEDFMKAVRKV 382
              .:|          ...:..|:..|.|||:.|.|.||.|.|.|....|:....|.:|:.:|
Yeast   477 --NLDPLLTDDMNNLSGKLATLTPGFTGADIANACNEAALIAARHNDPYITIHHFEQAIERV 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rpt4NP_572308.3 PRK03992 13..387 CDD:179699 97/257 (38%)
AFG3NP_010933.1 FtsH_ext 124..215 CDD:377663
FtsH_fam 223..730 CDD:273520 97/257 (38%)
Blue background indicates that the domain is not in the aligned region.

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