Protein Alignment Rpt4 and YME1

DIOPT Version :10

• Sequence 1: NP_572308.3
• Gene: Rpt4 / 31567
• FlyBaseID: FBgn0028685
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_015349.1
• Gene: YME1 / 856135
• SGDID: S000006228
• Length: 747
• Species: Saccharomyces cerevisiae
• Alignment Length: 294
• Identity: 99/294 - (33%)
• Similarity: 151/294 - (51%)
• Gaps: 36/294 - (12%)

  Fly   111 TTLTIMRYLPREVDPLVYNMSHEDPGDVTYSAIGGLTDQIRELREVIELPLLNPELFLRVGITPP 175
            |.|.......:.||....|:..:|        :.|..:...||.|:::. |.:|..:..:|...|
Yeast   259 TLLKSSEVADKSVDVAKTNVKFDD--------VCGCDEARAELEEIVDF-LKDPTKYESLGGKLP 314

  Fly   176 KGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMFNYARDHQPCIIFM 240
            ||.||.|||||||||||||.|.:...:|..:..|...:.|:|..|:.||::|..||...|.|||:
Yeast   315 KGVLLTGPPGTGKTLLARATAGEAGVDFFFMSGSEFDEVYVGVGAKRIRDLFAQARSRAPAIIFI 379

  Fly   241 DEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDTLDPALLRPGRLDR 305
            ||:|||||:|..:..:..::   ||.:||.::|||.....:.:|.|||.|:.||.||.||||.|:
Yeast   380 DELDAIGGKRNPKDQAYAKQ---TLNQLLVELDGFSQTSGIIIIGATNFPEALDKALTRPGRFDK 441

  Fly   306 KIEIPLPNEQARLEILKIHALKIAKHGEIDYEAIVKLSDNFNGADLRNVCTEAGLFAIR------ 364
            .:.:.||:.:.|.:|||.|..||.....:|...|.:.:...:||:|.|:..:|.::|.:
Yeast   442 VVNVDLPDVRGRADILKHHMKKITLADNVDPTIIARGTPGLSGAELANLVNQAAVYACQKNAVSV 506

  Fly   365 ---------------AEREYVIQEDFMKAVRKVS 383
                           |||:.::..|   |.||.:
Yeast   507 DMSHFEWAKDKILMGAERKTMVLTD---AARKAT 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt4	NP_572308.3	PRK03992	13..387	CDD:179699	99/294 (34%)
YME1	NP_015349.1	HflB	<269..709	CDD:440233	97/284 (34%)