Protein Alignment Rpt4 and Psmc5

DIOPT Version :10

• Sequence 1: NP_572308.3
• Gene: Rpt4 / 31567
• FlyBaseID: FBgn0028685
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_112411.1
• Gene: Psmc5 / 81827
• RGDID: 708376
• Length: 406
• Species: Rattus norvegicus
• Alignment Length: 357
• Identity: 179/357 - (50%)
• Similarity: 240/357 - (67%)
• Gaps: 5/357 - (1%)

  Fly    33 RLKEKREEIKDLTKLYDKSENDLKALQSVGQIVGEVLKQLTEDKFIVKATNGPRYVVGCRRQLDK 97
            ||:.:|.|:....:|.   ..:|:.||..|..||||::.:.:.|.:||.....::||...:.:|.
  Rat    44 RLQAQRNELNAKVRLL---REELQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDI 105

  Fly    98 AKLKSGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGDVTYSAIGGLTDQIRELREVIELPLL 162
            ..:....||||...:.|:.:.||.:|||||..|..|...|.||..||||..||:|::||||||:.
  Rat   106 NDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVK 170

  Fly   163 NPELFLRVGITPPKGCLLYGPPGTGKTLLARAVASQLDANFLKVVSSAIVDKYIGESARLIREMF 227
            :||||..:||..|||.||||||||||||||||||...|..|::|..|.:|.|:|||.||::||:|
  Rat   171 HPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELF 235

  Fly   228 NYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDSLGQVKMIMATNRPDT 292
            ..||:|.|.||||||||:||..|...|:..|.|:|||::|||||:|||::...:|:||||||.|.
  Rat   236 VMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDI 300

  Fly   293 LDPALLRPGRLDRKIEIPLPNEQARLEILKIHALKIAKHGEIDYEAIVKLSDNFNGADLRNVCTE 357
            ||.|||||||:|||||.|.|||:|||:|||||:.|:.....|:...|.:|....:||:::.||||
  Rat   301 LDSALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTE 365

  Fly   358 AGLFAIRAEREYVIQEDFMKAVRKV--SDNKK 387
            ||::|:|..|.:|.||||..||.||  .|::|
  Rat   366 AGMYALRERRVHVTQEDFEMAVAKVMQKDSEK 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt4	NP_572308.3	PRK03992	13..387	CDD:179699	178/355 (50%)
Psmc5	NP_112411.1	PRK03992	24..400	CDD:179699	179/357 (50%)
		May mediate interaction with PRPF9. /evidence=ECO:0000250|UniProtKB:P62196	186..406		121/212 (57%)