Protein Alignment CG3781 and JOSD1

DIOPT Version :8

• Sequence 1: NP_572303.4
• Gene: CG3781 / 31560
• FlyBaseID: FBgn0029853
• Length: 221
• Species: Drosophila melanogaster
• Sequence 2: NP_001347164.1
• Gene: JOSD1 / 9929
• HGNCID: 28953
• Length: 202
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 80/182 (44%)
• Similarity: 116/182 (64%)
• Gaps: 7/182 (4%)

  Fly    36 PHGIYHERQTRHLCGLHALNNLFQGPDMFSKSELDDYCTTLTPRNWLNPH-RSWIGWGNYDVNVI 99
            |..||||:|.|.||.||||||:||..:.|::..|.:....|:|...:.|| :|.:|.||||||||
Human    23 PPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSPNTMVTPHKKSMLGNGNYDVNVI 87

  Fly   100 MYALQQRNCEAVWFDRRRDPHCLNLSVIFGFILNVPAQMSLGYYIPLPFHMRHWLALRRLNGSYY 164
            |.|||.:..||||:|:|||...:.|:.:.|||:|:|:.:..| .:.||...:||:.:|.:.|:||
Human    88 MAALQTKGYEAVWWDKRRDVGVIALTNVMGFIMNLPSSLCWG-PLKLPLKRQHWICVREVGGAYY 151

  Fly   165 NLDSKLREPKCLGTEQQFLEFLATQLQ-MDHELFLVLDEETDCKDKSQQRW 214
            ||||||:.|:.:|.|.:..:||...|: .:.||.||:.||.:    :.|.|
Human   152 NLDSKLKMPEWIGGESELRKFLKHHLRGKNCELLLVVPEEVE----AHQSW 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3781	NP_572303.4	Josephin	44..184	CDD:280299	64/141 (45%)
JOSD1	NP_001347164.1	Josephin	35..173	CDD:307972	63/139 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C283137141
eggNOG	1	0.900				E1_KOG2934
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4181
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D1482722at2759
OrthoFinder	1	1.000				FOG0002402
OrthoInspector	1	1.000				T610341
orthoMCL	1	0.900				OOG5_130817
Panther	1	1.100			LDO	PTHR13291
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R8572
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	13	12.800