DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3781 and atxn3

DIOPT Version :9

Sequence 1:	NP_572303.4	Gene:	CG3781 / 31560	FlyBaseID:	FBgn0029853	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	XP_012823853.1	Gene:	atxn3 / 549143	XenbaseID:	XB-GENE-971501	Length:	357	Species:	Xenopus tropicalis

Alignment Length:	191	Identity:	50/191 - (26%)
Similarity:	78/191 - (40%)	Gaps:	43/191 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 IYHERQTRHLCGLHALNNLFQGPDMFSKSELDDYCTTLTPRNWL---------NPHRSWIGW--G 92
            |:||:|...||..|.||||.|| :.||..||......|..:..:         ..:|:::..  |
Frog     4 IFHEKQEGSLCAQHCLNNLLQG-EYFSPVELSSIAMQLDEQERMRMAEGGVTSEDYRTFVQQPSG 67

  Fly    93 NYD------VNVIMYALQQRNCEAVWFDRRRDPHCLNLSV----IFGFILNVPAQMSLGYYIPLP 147
            |.|      :.||..||.....|...|:   .|...||.:    ...||.|
Frog    68 NMDDSGFFSIQVISDALSVWGLELTLFN---SPEYRNLGIDPINEKAFICN-------------- 115

  Fly   148 FHMRHWLALRRLNGSYYNLDSKLREPKCLGTEQQFLEFLATQLQMD-HELFLVLDEETDCK 207
             :..||..:|:|...::||:|.|..|:.:  ...:|.....|||.: :.:|:|..:..:|:
Frog   116 -YKEHWFTVRKLGKQWFNLNSLLTGPELI--SDTYLALFLAQLQQEGYSIFVVKGDLPECE 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3781	NP_572303.4	Josephin	44..184	CDD:280299	40/160 (25%)
atxn3	XP_012823853.1	Josephin	9..163	CDD:280299	44/174 (25%)
atxn3	XP_012823853.1	SUIM_assoc	273..325	CDD:293225
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1482722at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010