DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4660 and them6

DIOPT Version :9

Sequence 1:	NP_572293.1	Gene:	CG4660 / 31542	FlyBaseID:	FBgn0029839	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001116176.1	Gene:	them6 / 569944	ZFINID:	ZDB-GENE-070912-340	Length:	205	Species:	Danio rerio

Alignment Length:	259	Identity:	73/259 - (28%)
Similarity:	110/259 - (42%)	Gaps:	66/259 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEQLCYLALSVLLAIIVVYGLLELHYFLRMCLCVLLARFVKRRCHILDTTTVNGLCLTNDVDTLL 65
            ||.:....:.|||   :::..|::.|:||..|.|..|.|:.....:....|.:|..:.||:|  |
Zfish     1 MEDVLLWVVGVLL---LLFCTLDVWYYLRAVLVVTKAWFLSPVFDVTGEQTASGRVVLNDID--L 60

  Fly    66 YHMNNARYFRELDFARVDFYERTNLYRTITGMGGSVFQGAATIRYRRFIRPFHRFNIISRIIYWD 130
            .|||||||.||.||||:..|.|..:::.:..:|.:...||.||||||.:.....|.:.|||:.||
Zfish    61 CHMNNARYLRECDFARLSLYTRNGVFKALRALGATAVVGATTIRYRRPLCVGEAFELRSRIVSWD 125

  Fly   131 EQSLFMEHRFVRPSDKFVHCIAICRQRVIDVSMEAVMSELLPRTSSNGFRATVLTSLAAPSPAAG 195
            |:|.::|.|||...|..|..:..|:|.|:..:.:.::..|..|
Zfish   126 EKSFYLEQRFVSCKDGMVSAVMFCKQNVLRSTPDKILQYLCKR---------------------- 168

  Fly   196 GISNPAMDTSLAENGHGTTSGGAAGTGATASATAAHCLKLK-PSLPPELAKWIEYNDMSSKNLR 258
                                                  |:: |..|.:|..||.:...|||.||
Zfish   169 --------------------------------------KVEVPEFPEDLQHWINFITASSKALR 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4660	NP_572293.1	4HBT_2	56..162	CDD:290018	45/105 (43%)
them6	NP_001116176.1	4HBT_2	53..183	CDD:290018	51/191 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581718
Domainoid	1	1.000	97	1.000	Domainoid score	I7172
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59462
OrthoDB	1	1.010	-	-		D1195870at2759
OrthoFinder	1	1.000	-	-		FOG0003421
OrthoInspector	1	1.000	-	-		mtm6532
orthoMCL	1	0.900	-	-		OOG6_106004
Panther	1	1.100	-	-	O	PTHR12475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2773
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.860