Protein Alignment CG5937 and syt22

DIOPT Version :10

• Sequence 1: NP_572289.2
• Gene: CG5937 / 31537
• FlyBaseID: FBgn0029834
• Length: 2051
• Species: Drosophila melanogaster
• Sequence 2: NP_594936.1
• Gene: syt22 / 2541783
• PomBaseID: SPAC11E3.11C
• Length: 942
• Species: Schizosaccharomyces pombe
• Alignment Length: 763
• Identity: 135/763 - (17%)
• Similarity: 228/763 - (29%)
• Gaps: 294/763 - (38%)

  Fly   735 ANVKHKEEEQLHDKR------------REAAKKLCRRLLTCCW---------------------- 765
            |.:|:......:|||            ..::|...:||....|
pombe     8 AYLKNGNSTPSNDKRSPSSLSQRSKTSTRSSKPFLQRLFPSTWFKNESSSRHPLTSIKENDTQTI 72

  Fly   766 ---DSMVIVL--------SSGLGDLQTSSASNKLVALSKRTLRVKAKANKSNGEALYAMCLD-GL 818
               .||.:.|        |....||.:...|..::..|..|.::...:|.|.......|..| |:
pombe    73 GRRPSMRVKLFGKDKSKASMSTNDLPSHPRSQSVMGFSSSTSQLTGTSNSSRTRLNKDMRRDFGM 137

  Fly   819 HSAATLSNS----------------------LNLQHLAGKILNLLASNVCQTSGPRISASQAMSM 861
            .|.:::::|                      |.....|..||:.|:.:         :::.|||.
pombe   138 TSMSSITSSTPTPSQLPVRPSTSLSFFDDIPLGPSFSAETILSSLSIS---------TSNNAMSK 193

  Fly   862 DVVLTGGLNLGSYSADCWPSIFAVCRHVSQLEHEIFSMQNPAISASPGSSR-------RDLETGE 919
            .......:...|.|||  ...|..|:.    |...:...|..|..||..||       ::|.|..
pombe   194 TTPAPPLVTTKSISAD--QDDFYTCKE----EVSTYEGLNSQIELSPVKSRDSQNKSAKNLSTAY 252

  Fly   920 KLSNGNAQDKL--------NLSSIPIDD------DETCVDVYSFLQAPMQSPNTNITSILKVYSG 970
            :..:|.:::.:        ..|..|:.|      |...::..|.|..|..:..|
pombe   253 RTVSGESRNLMVDPKVSPYGNSRTPLRDSSNYLRDRRSINRQSSLSIPKSTSET----------- 306

  Fly   971 TNETVLLS---------QSDTSKVLCALSHQAENLFGDAAERLSLPSLCQFLKHLCRASRDQLYK 1026
            |.:|:.||         .||:.||            .|::.:::...:.:..:|:  .|.|
pombe   307 TRKTLALSNGGIDQSRVSSDSFKV------------DDSSAKMAAIDIWEGSQHI--VSND---- 353

  Fly  1027 SQVARKGSRIWWPSKGWKKLDSLPMSLLLHRIGDVTLKVFRSSRPLLHVLKVWAITGPHLMDAAC 1091
                             |.|..|           ||.|.:..: .|.|.:.::......::.:.
pombe   354 -----------------KALSWL-----------VTDKPYNKA-VLKHYISLYDFENTDILQSL- 388

  Fly  1092 HRDRMISKRAIEYIHDIITALLVEQSELPYFHFNEALLKPFEN---------------------- 1134
               |||....  |:|.       |..||.:|      |..|.|
pombe   389 ---RMICGNL--YVHG-------ETQELDHF------LGEFSNQWCRTNPKGLFCNPQIVHSIAF 435

  Fly  1135 -LLSMDTDVDVQDQIVACLYEVVEAHRTEIRSGWRPLFGTLRNARSRMLNMSNIIDIFRVFLDSD 1198
             ||.::||:                |..|:            :|..||.....:.:.:|....:.
pombe   436 SLLLLNTDL----------------HIAEL------------SASERMSRNQFVENTYRSIKQAL 472

  Fly  1199 NTLVFANAGLDCILCLLSYLEISGGGNNNACSGGSGSAAGGTASNGGQQEEDNTFRPTDFLHE-- 1261
            |.....|........|.||...:   :|.:|:..:..:..|..|.|...|...       ||:
pombe   473 NDSFDGNEEKKNAFFLSSYKSFA---SNESCNSPAIHSLHGNLSPGKSAELKK-------LHKRS 527

  Fly  1262 -TLRFLERC------SSILGFMHSMPKCP------------NFHSTYKIKGISYTHIIDANIPSS 1307
             :.:.||..      |::....||:....            :|:.|.||           |.|||
pombe   528 LSSKVLEEAFSSYWMSALKEMYHSIKVSMILQPDRYLDMNFDFNDTNKI-----------NNPSS 581

  Fly  1308 MENFTYFGNDYLQTRNEQYMISYRSLHIDKDTIVKIDEMDKPSGVLKV 1355
            ..|         |||:...:...:.|.:..|.:.|  .|.:||..:.:
pombe   582 TAN---------QTRHFHSVSEIKKLPMGTDELEK--SMVRPSTAMYI 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5937	NP_572289.2	Sec7	451..692	CDD:469626
		DUF1981	1115..>1177	CDD:462756	13/84 (15%)
syt22	NP_594936.1	Sec7	296..499	CDD:214569	51/310 (16%)
		PH_9	679..804	CDD:434701