Protein Alignment CG5966 and LIPH

DIOPT Version :10

• Sequence 1: NP_572286.1
• Gene: CG5966 / 31532
• FlyBaseID: FBgn0029831
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_640341.1
• Gene: LIPH / 200879
• HGNCID: 18483
• Length: 451
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 134/457 - (29%)
• Similarity: 219/457 - (47%)
• Gaps: 71/457 - (15%)

  Fly    82 LHTRRALDQPKYLDLNDPESVQGMGMNPKGKIFLLVHGYLESGEIP-WMWDMAKALLAHEPEGRA 145
            |:||:.|...:.::    .|..| .:|...|...:|||:..:|..| ||.|:.|.||:.|.   .
Human    45 LYTRKNLTCAQTIN----SSAFG-NLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVED---M 101

  Fly   146 SVVLIDWGGGASP-PYVQAVANIRLVGAITAHVVHMLYEELRLPNLDNVHIIGHSLGAHLSGYAG 209
            :||::||..||:. .|..|.:..|.|..:....:..:..|  ..:||::::||.|||||:||:.|
Human   102 NVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAE--GASLDDIYMIGVSLGAHISGFVG 164

  Fly   210 YHLQHDFGLKPARITGLDPAAPLFTDTDPIVRLDKTDAHFVDIVHTDANPLMKGGLGINMRLGHV 274
            .  .:|..|  .||||||||.|||.......|||.:||.|||::|:|.:     .||....||::
Human   165 E--MYDGWL--GRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTD-----ALGYKEPLGNI 220

  Fly   275 DFFPNGGFDNPGCNKKFQDVVKKKTLFLTMQEFLGCNHIRSQQYFTESIGSQCPFLGITCDSFES 339
            ||:||||.|.|||         .||:....|.| .|:|.||...:..|:...|......|||::.
Human   221 DFYPNGGLDQPGC---------PKTILGGFQYF-KCDHQRSVYLYLSSLRESCTITAYPCDSYQD 275

  Fly   340 FKDTKCTSC-EEPGHTCLRMGYHSQEDYQEQVDLGQLQQGDSPGV--FYLWTGDSKPFCRLHYRI 401
            :::.||.|| .....:|..:||:: :::::.:      :|..|.:  .:..|.:..|||..||.:
Human   276 YRNGKCVSCGTSQKESCPLLGYYA-DNWKDHL------RGKDPPMTKAFFDTAEESPFCMYHYFV 333

  Fly   402 TVRVSGHDESTLHGGEVGILSIQLHDALVKKAGKNERAATEMMKFSQKAMYFEPGYEYKALVAGR 466
            .:.....:...      |.::|:|.|    |||.     |...|.:.:...|:. |...:|:|..
Human   334 DIITWNKNVRR------GDITIKLRD----KAGN-----TTESKINHEPTTFQK-YHQVSLLARF 382

  Fly   467 NLREPEYATVNWEYPT-NILNP--------LTWRILSAPR----IYLEYILIEAMESSDLYLKLC 518
            |....:.|.::..:.| :::.|        :..|.|:.|.    ...:.:|:|.:|:....: ||
Human   383 NQDLDKVAAISLMFSTGSLIGPRYKLRILRMKLRSLAHPERPQLCRYDLVLMENVETVFQPI-LC 446

  Fly   519 PQ 520
            |:
Human   447 PE 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5966	NP_572286.1	Pancreat_lipase_like	76..390	CDD:238363	103/312 (33%)
LIPH	NP_640341.1	Pancreat_lipase_like	39..303	CDD:238363	100/287 (35%)